1,112 research outputs found

    FAMILY STRUCTURE AND CHILD HEALTH OUTCOMES IN FRAGILE FAMILIES

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    Dramatic changes in family demography in the United States have led to increasing numbers of children living in “non-traditional” households. A large body of literature documents the association between living in a non-traditional family structure/familial instability and children’s cognitive and behavioral outcomes. In contrast, relatively little research has focused on the relationship between family structure and instability and children’s physical health outcomes, despite the fact that there is good theoretical reason to expect that family structure and instability might be associated with children’s physical health. The current study uses data from the Fragile Families and Child Wellbeing Study to assess whether family structure and familial instability are associated with a variety of children’s physical health outcomes. The paper pays particular attention to possible mediating mechanisms and utilizes longitudinal data to address potential problems of selection bias and reverse causality. The results suggest that children living with two married biological parents tend to fare better than children living in less traditional family structures across a variety of physical health outcomes, and that at least some portion of these relationships are likely the result of selection bias and/or reverse causality.

    Law & Order Made Amusing: A Selection of Law Books for Children from the Collection of Morris L. Cohen

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    Exhibition program from a Spring 1998 exhibit presented in the Daniel R. Coquillette Rare Book Room at the Boston College Law Library. The exhibit featured selections from Morris L. Cohen\u27s collection of law books for children

    Prospectus, May 14, 1980

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    GRADUATES, OR ALMOST GRADUATES, ARE LOOKING TO THE YEARS AHEAD; Intellectual Freedom Essay winner: Maybe they know something in the 2nd grade that we don\u27t; My momma was cumulus; Reporter blows it, Twist blues it; Stars highlight Sullivan; Staerkel bids farewell; Attention; Doomsday schedule; Letters to the Editor; It takes a week, but you can try out your water bed before you buy; Dates to live by; Classifieds; The softball nine win conference; Bench Warmer: LaBadie\u27s enthusiasm rubs off on athletes; Cobras beat Danville, 23-7; Complete Parkland Baseball Statisticshttps://spark.parkland.edu/prospectus_1980/1026/thumbnail.jp

    Lost in the system : responsibilisation and burden for women with multiple long-term health conditions during pregnancy

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    We would like to thank our patient and public involvement representatives for their input into the design, conduct and analysis of this work. Thanks also to our participants who took part in the study. This work was funded by the Strategic Priority Fund “Tackling multimorbidity at scale” programme (grant number MR/W014432/1) delivered by the Medical Research Council and the National Institute for Health Research in partnership with the Economic and Social Research Council and in collaboration with the Engineering and Physical Sciences Research Council.Peer reviewe

    Structural Characterization of the Interactions between Palladin and α-Actinin

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    The interaction between α-actinin and palladin, two actin-crosslinking proteins, is essential for proper bidirectional targeting of these proteins. As a first step toward understanding the role of this complex in organizing cytoskeletal actin, we have characterized binding interactions between the EF hand domain of α-actinin (Act-EF34) and peptides derived from palladin, and generated a NMR-derived structural model for the Act-EF34/palladin peptide complex. The critical binding site residues are similar to an actinin binding motif previously suggested for the complex between Act-EF34 and titin Z-repeats. The structure-based model of the Act-EF34/palladin peptide complex expands our understanding of binding specificity between the scaffold protein α-actinin and various ligands, which appears to require an α-helical motif containing four hydrophobic residues, common to many α–actinin ligands. We also provide evidence that the Family-X mutation in palladin, associated with a highly penetrant form of pancreatic cancer, does not interfere with α-actinin binding

    Examining public knowledge, attitudes and perceptions towards palliative care: a mixed method sequential study

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    Background: Palliative care is recognised as a public health issue with the need for earlier integration in the wider healthcare system. However, research indicates that it continues to be accessed late in the course of an illness, public understanding of palliative care is limited, and common misconceptions prevail. Strategies to address this are needed in order to reduce barriers to palliative care delivery and improve access. Methods: An explanatory sequential mixed methods study, comprising a cross-sectional survey and interviews was undertaken. Sociodemographic characteristics, public awareness, knowledge and perceptions of palliative care were examined and strategies to raise awareness and overcome barriers within a public health framework were identified. Survey data were analysed using SPSS v25 with factor analysis and non-parametric statistics and qualitative data were analysed using thematic analysis. Results: A total of 1201 participants completed the survey (58.3% female, mean age 61 years) and 25 took part in interviews. A fifth of participants (20.1%) had previously heard about palliative care and had an accurate understanding of the term. Being female, higher educated, married, and older, increased respondents’ levels of awareness. The three most commonly held misconceptions included: Palliative care is exclusively for people who are in the last 6 months of life (55.4% answered incorrectly); A goal of palliative care is to address any psychological issues brought up by serious illness (42.2% answered incorrectly); and a goal of palliative care is to improve a person’s ability to participate in daily activities (39.6% answered incorrectly). Talking about palliative and end of life care was advocated but societal taboos restricted this occurring with exposure limited to personal experience. Conclusions: Current knowledge gaps and misconceptions derived from limited ad hoc personal experiences and fear of engaging in taboo conversations may deter people from accessing integrated palliative care services early in a disease trajectory. The results indicate the need for public education programmes that move beyond merely raising awareness but provide key messages within a public health approach, which may change attitudes to palliative care thus ultimately improving end of life outcomes
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