5,259 research outputs found
Engaging parents in the drug education of their pre-adolescent children : Practical problems and a promising program
Team on teams: a collaborative inquiry
Over the course of an academic year, we collaborated to adopt a new instructional design for teams in our classes. We recount the story of our collaboration, outlining our process of inquiry, reflection, and support. Our simple search for better techniques shifted as our colleagues helped us reveal hidden assumptions about our roles as teachers. Our critical reflection allowed us to increase our self-awareness, specifically considering the following: how power influences our classroom interactions, how we contribute to and reinforce elements of the system that are not in our best interest, and the evolving stages of our own development as teachers. We believe our lessons will resonate with other teachers engaged in the challenges and rewards of self-development efforts
From Opportunity to Necessity: Development of an Asynchronous Online Interprofessional Learning Experience
Incorporating interprofessional collaboration competencies into both undergraduate pre-licensure and graduate health science students poses challenges for academic health science centers. Certain student groups may have less opportunity to participate in interprofessional learning experiences due to demands of individual programs of study and conflicts in scheduling time with other disciplines. A group of interprofessional higher education faculty members created an innovative online asynchronous interprofessional experience with the primary goals of meeting accreditation standards for specific programs and providing interprofessional education (IPE) to students who were unable to participate in traditional face-to-face IPE experiences already established at the institution. This guide will highlight the process of design and development of the learning opportunity, from conception to implementation. The pilot of the asynchronous online IPE experience served as a model for the transition of the original in-person model to virtual IPE during the COVID-19 pandemic
Transport and Retinal Capture of Lutein and Zeaxanthin with Reference to age-Related Macular Degeneration.
Abstract. Age-related macular degeneration (AMD) is the most common cause of irreversible blindness in the elderly population in the western world. The etiology and pathogenesis of this disease remain unclear. However, there is an increasing body of evidence supporting the hypothesis that the macular pigment carotenoids, lutein and zeaxanthin, play an important role in protection against AMD, by filtering out blue light at a pre-receptoral level, or by quenching free radicals. Lutein and zeaxanthin are dietary zanthophyll carotenoids, which are delivered to the retina via plasma lipoproteins. The biological mechanisms governing retinal capture and accumulation of lutein and zeaxanthin, to the exclusion of other carotenoids, are still poorly understood. Although these mechanisms remain unclear, it is possible that selective capture of these carotenoids is related to lipoprotein, apolipoprotein, function and profile. Xanthophyll-blinding proteins appear to play an important role in the retinal capture of the xanthophyll carotenoids. The Pi isoform of GSTP1 has been isolated as a specific binding protein for zeaxanthin. The binding protein responsible for retinal uptake of lutein remains elusive. This article reviews the literature germane to the mechanisms involved in the capture, accumulation and stabilization of lutein and zeaxanthin by the retina, and the processes nvolvedin their transport in serum
The paradox of invasion:Reeves' muntjac deer invade the British Isles from a limited number of founding females
The relationship between macular pigment optical density and its constituent carotenoids in diet and serum
PURPOSE: Lutein (L) and zeaxanthin (Z) are two dietary carotenoids that accumulate at the macula, where they are collectively known as macular pigment (MP). There is a biologically plausible rationale, with some supporting evidence, that MP may protect against age-related maculopathy (ARM). This study was undertaken to investigate the relationship between dietary intake of L and Z, serum concentrations of these carotenoids, and MP optical density in 828 healthy Irish subjects. METHODS: Dietary intake of L and Z was assessed with a validated food-frequency questionnaire, and serum concentrations of these carotenoids were quantified by high-performance liquid chromatography. MP optical density was measured psychophysically, using heterochromatic flicker photometry. Demographic data, lifestyle data, and general health status, were also recorded by questionnaire, with particular attention directed toward risk-factors (established and putative) for ARM. RESULTS: The relationships between MP optical density, serum concentrations of L (and Z), and dietary intake of L (and Z) were positive and statistically significant when analyzed for the entire study group (r = 0.136-0.303; P 27, did not demonstrate a positive and significant relationship between MP optical density and serum concentrations of Z (r = 0.041, r = 0.001, r = 0.074 and r = 0.082, respectively; P > 0.05 for all). However, there was a positive and significant relationship between MP optical density and serum concentrations of L in the presence of all these risk factors (r = 0.165 to 0.257), except for current heavy smokers (r = 0.042; P > 0.05). CONCLUSIONS: For subjects at increased risk of ARM (e.g., subjects with a clinically confirmed family history of ARM, current heavy cigarette smokers, subjects aged > 53 years and subjects with a BMI > 27) retinal capture and/or retinal stabilization of Z appears to be compromised, whereas retinal uptake and/or stabilization of L appears to be compromised in current heavy smokers only. Given the lack of MP in association with risk for ARM, the findings indicate that a retina predisposed to this condition may have an impaired ability to accumulate circulating Z
The Energy Spectra and Relative Abundances of Electrons and Positrons in the Galactic Cosmic Radiation
Observations of cosmic-ray electrons and positrons have been made with a new
balloon-borne detector, HEAT (the "High-Energy Antimatter Telescope"), first
flown in 1994 May from Fort Sumner, NM. We describe the instrumental approach
and the data analysis procedures, and we present results from this flight. The
measurement has provided a new determination of the individual energy spectra
of electrons and positrons from 5 GeV to about 50 GeV, and of the combined
"all-electron" intensity (e+ + e-) up to about 100 GeV. The single power-law
spectral indices for electrons and positrons are alpha = 3.09 +/- 0.08 and 3.3
+/- 0.2, respectively. We find that a contribution from primary sources to the
positron intensity in this energy region, if it exists, must be quite small.Comment: latex2e file, 30 pages, 15 figures, aas2pp4.sty and epsf.tex needed.
To appear in May 10, 1998 issue of Ap.
Planning the Future of U.S. Particle Physics (Snowmass 2013): Chapter 4: Cosmic Frontier
These reports present the results of the 2013 Community Summer Study of the
APS Division of Particles and Fields ("Snowmass 2013") on the future program of
particle physics in the U.S. Chapter 4, on the Cosmic Frontier, discusses the
program of research relevant to cosmology and the early universe. This area
includes the study of dark matter and the search for its particle nature, the
study of dark energy and inflation, and cosmic probes of fundamental
symmetries.Comment: 61 page
The ROTSE-III Robotic Telescope System
The observation of a prompt optical flash from GRB990123 convincingly
demonstrated the value of autonomous robotic telescope systems. Pursuing a
program of rapid follow-up observations of gamma-ray bursts, the Robotic
Optical Transient Search Experiment (ROTSE) has developed a next-generation
instrument, ROTSE-III, that will continue the search for fast optical
transients. The entire system was designed as an economical robotic facility to
be installed at remote sites throughout the world. There are seven major system
components: optics, optical tube assembly, CCD camera, telescope mount,
enclosure, environmental sensing & protection and data acquisition. Each is
described in turn in the hope that the techniques developed here will be useful
in similar contexts elsewhere.Comment: 19 pages, including 4 figures. To be published in PASP in January,
2003. PASP Number IP02-11
Putting the squeeze on "Generation Rent": housing benefit claimants in the private rented sector - transitions, marginality and stigmatisation
The term 'Generation Rent' has gained currency in recent years to reflect the fact that more 25 to 34 year olds in Britain now live in rented accommodation rather than owner-occupation. The term also conveys the extent to which age-related divisions in the housing market are becoming as significant as longer standing tenure divisions. However, this portmanteau term covers a wide array of different housing circumstances - from students, young professionals and transient households to the working and non-working poor. This paper focuses on the position of a specific category of this age cohort - those 25 to 34 year olds living in self-contained accommodation in the private rented sector who are in receipt of Housing Benefit. On the basis of survey evidence and qualitative interviews with landlords and housing advisers, the paper considers how the marginal economic and housing market position of this age group is being reinforced by the stigmatising attitudes of landlords which formerly applied to tenants in their late teens and early 20s and are now being extended further along the age band. The paper suggests that the use of a 'housing pathways' approach to signify the housing transitions of young adults needs to be revisited, to give greater weight to collective and creative responses to constraints in the housing market and to recognise the key role played by gatekeepers such as landlords in stigmatising groups according to assumed age-related attributes
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