2,024 research outputs found

    Neutrinos from Early-Phase, Pulsar-Driven Supernovae

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    Neutron stars, just after their formation, are surrounded by expanding, dense, and very hot envelopes which radiate thermal photons. Iron nuclei can be accelerated in the wind zones of such energetic pulsars to very high energies. These nuclei photo-disintegrate and their products lose energy efficiently in collisions with thermal photons and with the matter of the envelope, mainly via pion production. When the temperature of the radiation inside the envelope of the supernova drops below 3×106\sim 3\times 10^6 K, these pions decay before losing energy and produce high energy neutrinos. We estimate the flux of muon neutrinos emitted during such an early phase of the pulsar - supernova envelope interaction. We find that a 1 km2^2 neutrino detector should be able to detect neutrinos above 1 TeV within about one year after the explosion from a supernova in our Galaxy. This result holds if these pulsars are able to efficiently accelerate nuclei to energies 1020\sim 10^{20} eV, as postulated recently by some authors for models of Galactic acceleration of the extremely high energy cosmic rays (EHE CRs).Comment: 16 pages, 3 figures, revised version submitted to Ap

    BMED 613.01: Pharmacology

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    Peer review quality and transparency of the peer-review process in open access and subscription journals

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    BACKGROUND:Recent controversies highlighting substandard peer review in Open Access (OA) and traditional (subscription) journals have increased the need for authors, funders, publishers, and institutions to assure quality of peer-review in academic journals. I propose that transparency of the peer-review process may be seen as an indicator of the quality of peer-review, and develop and validate a tool enabling different stakeholders to assess transparency of the peer-review process. METHODS AND FINDINGS:Based on editorial guidelines and best practices, I developed a 14-item tool to rate transparency of the peer-review process on the basis of journals' websites. In Study 1, a random sample of 231 authors of papers in 92 subscription journals in different fields rated transparency of the journals that published their work. Authors' ratings of the transparency were positively associated with quality of the peer-review process but unrelated to journal's impact factors. In Study 2, 20 experts on OA publishing assessed the transparency of established (non-OA) journals, OA journals categorized as being published by potential predatory publishers, and journals from the Directory of Open Access Journals (DOAJ). Results show high reliability across items (α = .91) and sufficient reliability across raters. Ratings differentiated the three types of journals well. In Study 3, academic librarians rated a random sample of 140 DOAJ journals and another 54 journals that had received a hoax paper written by Bohannon to test peer-review quality. Journals with higher transparency ratings were less likely to accept the flawed paper and showed higher impact as measured by the h5 index from Google Scholar. CONCLUSIONS:The tool to assess transparency of the peer-review process at academic journals shows promising reliability and validity. The transparency of the peer-review process can be seen as an indicator of peer-review quality allowing the tool to be used to predict academic quality in new journals

    Methods of Curing Lamb for Farm Family Use in Oklahoma

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    The Oklahoma Agricultural Experiment Station periodically issues revisions to its publications. The most current edition is made available. For access to an earlier edition, if available for this title, please contact the Oklahoma State University Library Archives by email at [email protected] or by phone at 405-744-6311

    Expression of divIB of Bacillus subtilis during vegetative growth

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    Expression of the division initiation gene, divIB, of Bacillus subtilis vegetative growth was examined. lacZ fusion studies and transcription start point mapping have established that a sigma A promoter proximal to divIB is utilized in vivo. The -10 region of this promoter, which is located 93 bp upstream of the start codon, has been defined precisely by site-directed mutagenesis that destroys the promoter. Examination of transcripts by Northern (RNA) blotting has shown that there are at least two transcripts for divIB. The established proximal promoter was found to give rise to a very minor transcript which could not be convincingly demonstrated in wild-type cells but which became apparent upon insertion of a plasmid into the chromosome just upstream of this promoter. The major transcript for divIB originated from a site several kb upstream of the gene and is probably the same as the long polycistronic message also traversing the murD-spoVE-murG genes that was identified previously by others (A.D. Henriques, H. de Lencastre, and P.J. Piggot, Biochimie 74:735-748, 1992). Transcription from the proximal promoter alone, in an upstream-deletion mutant strain, provided sufficient DivIB for normal growth and division as well as sporulation

    Realism, Objectivity, and Evaluation

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    I discuss Benacerraf's epistemological challenge for realism about areas like mathematics, metalogic, and modality, and describe the pluralist response to it. I explain why normative pluralism is peculiarly unsatisfactory, and use this explanation to formulate a radicalization of Moore's Open Question Argument. According to the argument, the facts -- even the normative facts -- fail to settle the practical questions at the center of our normative lives. One lesson is that the concepts of realism and objectivity, which are widely identified, are actually in tension
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