Onset of η\eta-nuclear binding in a pionless EFT approach

$\eta NNN$ and $\eta NNNN$ bound states are explored in stochastic variational method (SVM) calculations within a pionless effective field theory (EFT) approach at leading order. The theoretical input consists of regulated $NN$ and $NNN$ contact terms, and a regulated energy dependent $\eta N$ contact term derived from coupled-channel models of the $N^{\ast}(1535)$ nucleon resonance plus a regulated $\eta NN$ contact term. A self consistency procedure is applied to deal with the energy dependence of the $\eta N$ subthreshold input, resulting in a weak dependence of the calculated $\eta$-nuclear binding energies on the EFT regulator. It is found, in terms of the $\eta N$ scattering length $a_{\eta N}$, that the onset of binding \eta\,^3He requires a minimal value of Re$\,a_{\eta N}$ close to 1 fm, yielding then a few MeV $\eta$ binding in \eta\,^4He. The onset of binding \eta\,^4He requires a lower value of Re$\,a_{\eta N}$, but exceeding 0.7 fm.Comment: v4 consists of the published Physics Letters B version [31] plus Erratum ([30], Appendix A here); main results and conclusions remain intac

Eta-mesic nuclei

In this contribution we report on theoretical studies of $\eta$ nuclear quasi-bound states in few- and many-body systems performed recently by the Jerusalem-Prague Collaboration [1-5]. Underlying energy-dependent $\eta N$ interactions are derived from coupled-channel models that incorporate the $N^*(1535)$ resonance. The role of self-consistent treatment of the strong energy dependence of subthreshold $\eta N$ amplitudes is discussed. Quite large downward energy shift together with rapid decrease of the $\eta N$ amplitudes below threshold result in relatively small binding energies and widths of the calculated $\eta$ nuclear bound states. We argue that the subthreshold behavior of $\eta N$ scattering amplitudes is crucial to conclude whether $\eta$ nuclear states exist, in which nuclei the $\eta$ meson could be bound and if the corresponding widths are small enough to allow detection of these $\eta$ nuclear states in experiment.Comment: 7 pages, 5 figures; presented at HADRON2017, Sept. 25-29, 2017, Salamanca (Spain); prepared for Proceedings of Scienc

Efimov physics beyond three particles

Efimov physics originally refers to a system of three particles. Here we review recent theoretical progress seeking for manifestations of Efimov physics in systems composed of more than three particles. Clusters of more than three bosons are tied to each Efimov trimer, but no independent Efimov physics exists there beyond three bosons. The case of a few heavy fermions interacting with a lighter atom is also considered, where the mass ratio of the constituent particles plays a significant role. Following Efimov's study of the (2+1) system, the (3+1) system was shown to have its own critical mass ratio to become Efimovian. We show that the (4+1) system becomes Efimovian at a mass ratio which is smaller than its sub-systems thresholds, giving a pure five-body Efimov effect. The (5+1) and (6+1) systems are also discussed, and we show the absence of 6- and 7-body Efimov physics there

RNA editing signature during myeloid leukemia cell differentiation

Adenosine deaminases acting on RNA (ADARs) are key proteins for hematopoietic stem cell self-renewal and for survival of differentiating progenitor cells. However, their specific role in myeloid cell maturation has been poorly investigated. Here we show that ADAR1 is present at basal level in the primary myeloid leukemia cells obtained from patients at diagnosis as well as in myeloid U-937 and THP1 cell lines and its expression correlates with the editing levels. Upon phorbol-myristate acetate or Vitamin D3/granulocyte macrophage colony-stimulating factor (GM-CSF)-driven differentiation, both ADAR1 and ADAR2 enzymes are upregulated, with a concomitant global increase of A-to-I RNA editing. ADAR1 silencing caused an editing decrease at specific ADAR1 target genes, without, however, interfering with cell differentiation or with ADAR2 activity. Remarkably, ADAR2 is absent in the undifferentiated cell stage, due to its elimination through the ubiquitin–proteasome pathway, being strongly upregulated at the end of the differentiation process. Of note, peripheral blood monocytes display editing events at the selected targets similar to those found in differentiated cell lines. Taken together, the data indicate that ADAR enzymes play important and distinct roles in myeloid cells

Corrigendum to âOnset of η-nuclear binding in a pionless EFT approachâ [Phys. Lett. B 771 (2017) 297â302]

A three-body force acting between the η-meson and two nucleons was overlooked inadvertently in the model description and discussion in the published version of our paper âOnset of η-nuclear binding in a pionless EFT approachâ [Phys. Lett. B 771 (2017) 297â302] while present in the actual numerical calculations. The stated conclusion that a stabilizing ηNN contact term was not needed is therefore incorrect. Such a three-body force, associated with a new low energy constant dηNNÎ, must be introduced at leading order to stabilize η-nucleus systems. Keywords: Few-body systems, Mesic nuclei, Ï̸EFT calculation