Human Activity in Palaeolithic Period in Çanakkale Province

It is acknowledged in the light of today's information that human species first appeared in Africa and spread to other parts of the world. It is one of the most important issues to determine which routes human species took during this process and where their living areas were located. Due to its position between Africa, Asia and Europe, the Anatolian peninsula is a region of critical importance for the investigation of this issue. In Çanakkale province, which is located in a key region in terms of fossil human population spread to Europe, 40 locality where Paleolithic chipped stone finds were found were determined during the surveys carried out between 2014 and 2017. This number is expected to increase as a result of the research to be carried out in the following years. During these researches, 16 caves were found and excavations were initiated in İnkaya Cave, which has an intensive human settlement. In this study, field surveys in Çanakkale province that have been ongoing for 4 seasons and the fossil human traces in the light of the findings obtained from these studies are discussed

A case series of Turkish children and adolescents with bipolar spectrum disorder: A naturalistic clinical phenomenological follow-up

Aim. The main objectives of this a naturalistic, prospective follow-up study were to describe the clinical presentation and predictors of treatment response in Turkish children and adolescents with bipolar disorde (BD) and to document their response to available treatment regimes. Methods. The study sample consisted of 27 consecutive admissions to the Child and Adolescent Psychiatry Clinic between 2002 and 2006. Washington University at St Louis -Kiddie and Young Adult Schedule for Affective Disorders and Schizophrenia (WASH-U-KSADS) was administered to mothers for an assessment of the problem of their children and to children about themselves. Subjects were phenomenologically re-examined to ascertain whether they met the Leibenluft criteria for the narrow, intermediate, or broad phenotypes of juvenile mania. All patients were also rated with Children Global Assesment Scale (CGAS) and Young Mania Rating Scale (YMRS). Treatment response was documented using the Clinical Global Impression (CGI) and the YMRS. Results. The mean age was 12.95±3.8 years and the mean follow-up period was 24±9.2 months. Nineteen (70.3%) patients continued their treatment for 20.6±12.47 months. A large number of patients responded to mood stabilizers and antipsychotic agents (89.5%). When treatment endpoint scores of CGAS were compared between patients with age at onset ≥13 and <13, functionality of group with age at onset ≥13 was significantly greater than early onset group at the end of the treatment(z:-2.014, P=0.044). Conclusion. Compared to non-episodic patients, episodic patients were more likely to have psychotic features and to have a later age of onset. Mood stabilizers and atypical antipsychotic combination was required in many cases (73.7%). Long term follow-up clinical phenomenological and treatment efficacy studies are needed in the future