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Using airborne laser altimetry to improve river flood extents delineated from SAR data
Flood extent maps derived from SAR images are a useful source of data for validating hydraulic models of river flood flow. The accuracy of such maps is reduced by a number of factors, including changes in returns from the water surface caused by different meteorological conditions and the presence of emergent vegetation. The paper describes how improved accuracy can be achieved by modifying an existing flood extent delineation algorithm to use airborne laser altimetry (LiDAR) as well as SAR data. The LiDAR data provide an additional constraint that waterline (land-water boundary) heights should vary smoothly along the flooded reach. The method was tested on a SAR image of a flood for which contemporaneous aerial photography existed, together with LiDAR data of the un-flooded reach. Waterline heights of the SAR flood extent conditioned on both SAR and LiDAR data matched the corresponding heights from the aerial photo waterline significantly more closely than those from the SAR flood extent conditioned only on SAR data
Strong Shift Equivalence of -correspondences
We define a notion of strong shift equivalence for -correspondences and
show that strong shift equivalent -correspondences have strongly Morita
equivalent Cuntz-Pimsner algebras. Our analysis extends the fact that strong
shift equivalent square matrices with non-negative integer entries give stably
isomorphic Cuntz-Krieger algebras.Comment: 26 pages. Final version to appear in Israel Journal of Mathematic
On the spectral properties of L_{+-} in three dimensions
This paper is part of the radial asymptotic stability analysis of the ground
state soliton for either the cubic nonlinear Schrodinger or Klein-Gordon
equations in three dimensions. We demonstrate by a rigorous method that the
linearized scalar operators which arise in this setting, traditionally denoted
by L_{+-}, satisfy the gap property, at least over the radial functions. This
means that the interval (0,1] does not contain any eigenvalues of L_{+-} and
that the threshold 1 is neither an eigenvalue nor a resonance. The gap property
is required in order to prove scattering to the ground states for solutions
starting on the center-stable manifold associated with these states. This paper
therefore provides the final installment in the proof of this scattering
property for the cubic Klein-Gordon and Schrodinger equations in the radial
case, see the recent theory of Nakanishi and the third author, as well as the
earlier work of the third author and Beceanu on NLS. The method developed here
is quite general, and applicable to other spectral problems which arise in the
theory of nonlinear equations
Evaluation of competences at the community pharmacy settings
The General Level Framework (GLF) document provides a model to be used in evaluating and upgrading of pharmacistsā competences currently used in many countries. This study has several Objectives: To show the adaptation process of the GLF document to the Serbian pharmaceutical work practices and regulations; to illustrate the implementation of the GLF document; to evaluate and monitor the development of pharmacistsā competencies. Materials and Methods: The adaptation, analysis, validation and adjustment of the GLF document were conducted using the expert panel method. The implementation was conducted on a sample of pharmacists employed in Subotica Pharmacy chain. Later, the evaluation of the pharmacistsā competencies was performed at two observation points (at the beginning of the study and after 6 months) by the team of seven GLF members. Results and Discussion: The GLF document was reviewed by 14 members of the expert panel. During the content validation performed at the expert panel meeting, all competencies stated in the GLF document were rated according to their importance with an average grade of between 8.26 and 9.80 and thus reached a consensus regarding all 26 competencies. During the evaluation of the pharmacistsā competences, the greatest improvement after the second observation was noted in the āPatient consentā competency, followed by the āDrug historyā, āThe prescription is legalā, āHealth needsā, āProvision of written informationā and āAssessing outcomes of contributionsā competencies. All the competencies in the GLF document were accepted for the implementation in the Subotica Pharmacy chain. Six of the competencies there was a significant improvement observed
Clinical outcome data for symptomatic breast cancer: the breast cancer clinical outcome measures (BCCOM) project
Background: Data collection for screen-detected breast cancer in the UK is fully funded which has led to improvements in clinical practice. However data on symptomatic breast cancer are deficient, and the aim of this project was to monitor the current practice.
Methods: A data set was designed together with surrogate outcome measures to reflect best practice. Data from cancer registries initially required the consent of clinicians, but in the third year anonymised data were available.
Results: The quality of data improved but this varied by region and only a third of cases were validated by clinicians. Regional variations in mastectomy rates were identified and one third of patients who underwent conservative surgery for invasive breast cancer were not recorded as receiving radiotherapy.
Conclusions: National data are essential to ensure that all patients receive appropriate treatment for breast cancer, but variations still exist in the UK and further improvement in data capture is required
Interactive effects between group and single-subject response patterns
A two-part study was undertaken to investigate the effects of movement experiences on lower extremity function during impact activities. Group and single-subject performances were evaluated for a total of 12 male volunteers during landing (Study I) and running (Study II) activities. Standard biomechanical techniques were used to obtain kinematic (200 Hz) and kinetic (1000 Hz) data during soft, normal and stiff-knee landings (Study I) and for under, normal, and over-stride running (Study II). Performance trials were tested for normality, condition differences were documented and multiple regression models were computed to predict the first (F1) and second (F2) maximum vertical forces during landing and the maximum impact force (IF) during running. Results of the study identified condition differences with no deviations from normality, thereby achieving the goal of increasing performance heterogeneity to benefit the modeling procedures. Group regression model results for F1, F2 and IF each identified a single predictor variable that accounted for 74.7, 98.6 and 81.6% explained variance (EV), respectively. Single-subject predictors and EV values varied and demonstrated a number of different strategies. The group models were not representative of any of the individual subjects\u27 performances and indicate that group models can describe a mythical average performer. These results suggest that researchers must be cautious when evaluating group performance patterns
The geometry of nonlinear least squares with applications to sloppy models and optimization
Parameter estimation by nonlinear least squares minimization is a common
problem with an elegant geometric interpretation: the possible parameter values
of a model induce a manifold in the space of data predictions. The minimization
problem is then to find the point on the manifold closest to the data. We show
that the model manifolds of a large class of models, known as sloppy models,
have many universal features; they are characterized by a geometric series of
widths, extrinsic curvatures, and parameter-effects curvatures. A number of
common difficulties in optimizing least squares problems are due to this common
structure. First, algorithms tend to run into the boundaries of the model
manifold, causing parameters to diverge or become unphysical. We introduce the
model graph as an extension of the model manifold to remedy this problem. We
argue that appropriate priors can remove the boundaries and improve convergence
rates. We show that typical fits will have many evaporated parameters. Second,
bare model parameters are usually ill-suited to describing model behavior; cost
contours in parameter space tend to form hierarchies of plateaus and canyons.
Geometrically, we understand this inconvenient parametrization as an extremely
skewed coordinate basis and show that it induces a large parameter-effects
curvature on the manifold. Using coordinates based on geodesic motion, these
narrow canyons are transformed in many cases into a single quadratic, isotropic
basin. We interpret the modified Gauss-Newton and Levenberg-Marquardt fitting
algorithms as an Euler approximation to geodesic motion in these natural
coordinates on the model manifold and the model graph respectively. By adding a
geodesic acceleration adjustment to these algorithms, we alleviate the
difficulties from parameter-effects curvature, improving both efficiency and
success rates at finding good fits.Comment: 40 pages, 29 Figure
Finite to infinite steady state solutions, bifurcations of an integro-differential equation
We consider a bistable integral equation which governs the stationary
solutions of a convolution model of solid--solid phase transitions on a circle.
We study the bifurcations of the set of the stationary solutions as the
diffusion coefficient is varied to examine the transition from an infinite
number of steady states to three for the continuum limit of the
semi--discretised system. We show how the symmetry of the problem is
responsible for the generation and stabilisation of equilibria and comment on
the puzzling connection between continuity and stability that exists in this
problem
Brighter prospects? Assessing the franchise advantage using census data
This paper uses Census micro data to examine how starting a business as a franchise rather than an independent business affects its survival and growth prospects. We assess factors that influence the decision to become a franchisee and use various empirical approaches to correct for selection bias in our performance analyses. We find that franchised businesses on average exhibit higher survival rates than independent businesses, but importantly, the difference is small compared to claims in the trade press. The effect is also short lived: conditional on surviving a year or two, we no longer find survival (or growth) differences. We then explore two potential sources for this small survival advantage, namely franchisorsā screening process and the benefits arising from the brand and business know-how provided by franchisors. We find evidence that both of the sources contribute to the franchising advantage
Directed motion emerging from two coupled random processes: Translocation of a chain through a membrane nanopore driven by binding proteins
We investigate the translocation of a stiff polymer consisting of M monomers
through a nanopore in a membrane, in the presence of binding particles
(chaperones) that bind onto the polymer, and partially prevent backsliding of
the polymer through the pore. The process is characterized by the rates: k for
the polymer to make a diffusive jump through the pore, q for unbinding of a
chaperone, and the rate q kappa for binding (with a binding strength kappa);
except for the case of no binding kappa=0 the presence of the chaperones give
rise to an effective force that drives the translocation process. Based on a
(2+1) variate master equation, we study in detail the coupled dynamics of
diffusive translocation and (partial) rectification by the binding proteins. In
particular, we calculate the mean translocation time as a function of the
various physical parameters.Comment: 22 pages, 5 figures, IOP styl
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