5 research outputs found

    Drowning in Sacrifice: Maggie Tulliver’s Role in George Eliot’s The Mill on the Floss

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    Upon examining the personal rejection and eventual demise of Maggie Tulliver, the protagonist of The Mill on the Floss, it becomes evident that her death is a sacrifice through which she demonstrates the morality of George Eliot’s religion of humanity. Maggie is a headstrong, intelligent, and memorable character who does not fit into her community and ultimately drowns in a flood while attempting to save her loved ones. The story begs the question: why must such an endearing main character perish? One possibility is that her character flaws make her downfall inevitable. The high-class and hypocritical members of the town of St. Ogg’s exile Maggie because she is too different and too desperate for love. Others may argue that Maggie’s death is a consequence of natural selection. The daughter of two very disparate family lines, her mixed blood results in a temperament that does not belong in her society. The survival of the fittest hypothesis, therefore, requires her passing. In actuality, Maggie’s demise is not due to character flaws or nature’s dictates. Rather, it is a demonstration of the sacrificial love of the religion of humanity. Eliot herself had given up orthodox Christianity in favor of a religion of humanity that advocated human love and selflessness without religious dogma. In The Mill on the Floss, Eliot presents a society that has also outgrown religion. Maggie, who does not find comfort in an outmoded religion or a judgmental society, is the only person who can demonstrate the ideology that this post-Christian town should embrace. The sacrifices that result in her downfall and her unfortunate death are demonstrations of selfless love. Eliot’s memorable protagonist must suffer and die as a voice espousing the values of her religion of humanity

    Finishing the euchromatic sequence of the human genome

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    The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

    Binding of the Proline-Rich Segment of Myelin Basic Protein to SH3 Domains: Spectroscopic, Microarray, and Modeling Studies of Ligand Conformation and Effects of Posttranslational Modifications

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    Essential oils and related products

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    FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy?

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