431 research outputs found
Barbiturates for the treatment of intracranial hypertension after traumatic brain injury
In their article on the use of barbiturates for the treatment of intracranial hypertension after traumatic brain injury, Perez-Barcena and colleagues conclude that thiopental was more effective than pentobarbital in decreasing intracranial pressure. Here we discuss the limitations of this study and review areas of controversy surrounding barbiturate use in neurocritical care
Characterization of RNA from Noninfectious Virions Produced by Sarcoma Positive-Leukemia Negative Transformed 3T3 Cells
Endocrine disrupting chemicals removal in an aerobic granular sludge reactor treating simulated saline wastewater
The occurrence of Endocrine disrupting chemicals (EDCs) in the environment is a topic of concern. It is commonly accepted that the major source of EDCs to the environment is wastewater treatment plants effluents. Salinity is an additional common stress factor in wastewater treatment. Aerobic granular sludge (AGS) has a number of properties that make it more attractive than conventional biological systems for treatment of wastewater containing EDCs. In the present study, an AGS sequencing batch reactor adapted to salinity was operated for 140 days for treating synthetic saline wastewater containing 17β–estradiol (E2), 17α–ethinylestradiol (EE2) and bisphenol-A (BPA). E2 was removed by biodegradation. EE2 adsorption/desorption to the aerobic granules was observed. The increasing of BPA removal efficiency after bioaugmentation with a degrading bacterial strain shows that biodegradation was the removal mechanism. COD removal was not significantly affected by EDCs shock loads. Activity of ammonia oxidizing bacteria and nitrite oxidizing bacteria did not seem to be inhibited by the presence of EDCs. The activity of phosphate accumulating organisms was affected.info:eu-repo/semantics/publishedVersio
Bacterial strain rhodococcus sp. ED55 degrades endocrine disrupring chemicals in wastewater
info:eu-repo/semantics/publishedVersio
Rhodococcus sp. ED55: a bacterial strain with ability to degrade endocrine disrupting chemicals and potential for bioaugmentation
The occurrence of Endocrine disrupting chemicals (EDCs) in the environment is a topic of concern. It is commonly accepted that the major source of EDCs to the environment is wastewater treatment plants (WWTPs’) effluents, due to the inefficiency of WWTPs to remove this kind of pollutants. A bacterial strain – Rhodococcus sp. ED55 was isolated from the sediments of a discharge point of a WWTP in Coloane, Macau, for its ability to degrade EDCs. The bacterium was able to biodegrade 17β–estradiol (E2), 17α–ethinylestradiol (EE2), bisphenol-A (BPA) and bisphenol-S (BPS) at different extents. Strain ED55 was able to completely degrade the supplied amount of E2 in few hours, both in synthetic medium and in real wastewater from a municipal WWTP (Parada, Maia – Portugal). Estrone (E1), 4OH-E1 and 4OH-E2 were identified as intermediate degradation metabolites and the metabolic pathway is under elucidation. Bioaugmentation with Rhodococcus sp. ED 55 significantly improved the natural attenuation of the compound in municipal wastewater in batch assays. The acute test with luminescent marine bacterium Vibrio fischeri revealed elimination of the toxicity of the treated effluent and the standardized yeast estrogenic (S-YES) assay with the recombinant strain of Saccharomyces cerevisiae revealed decrease of estrogenic activity of samples. Rhodococcus sp. ED55 was applied in a strategy of an AGS sequencing batch reactor adapted to salinity, which was operated for treating a synthetic saline wastewater containing E2, EE2 and BPA. E2 was no longer detected in the bulk liquid after 10 min of aerobic reaction throughout reactor operation, suggesting that this compound was quickly removed by biodegradation. EE2 adsorption/desorption to the aerobic granules was observed. Removal of BPA significantly increased after bioaugmentation with Rhodococcus sp. ED55, showing that biodegradation was the governing removal mechanism. COD removal was not significantly affected by EDCs shock loads. Rhodococcus sp. ED55 can potentially be applied in bioaugmentation strategies for ameliorating treatment of wastewater contaminated with EDCs.info:eu-repo/semantics/publishedVersio
Rhodococcus sp. ED55: a bacterial strain with potential for application in wastewater treatment for effective removal of endocrine disruptors
info:eu-repo/semantics/publishedVersio
Geo-neutrinos: A systematic approach to uncertainties and correlations
Geo-neutrinos emitted by heat-producing elements (U, Th and K) represent a
unique probe of the Earth interior. The characterization of their fluxes is
subject, however, to rather large and highly correlated uncertainties. The
geochemical covariance of the U, Th and K abundances in various Earth
reservoirs induces positive correlations among the associated geo-neutrino
fluxes, and between these and the radiogenic heat. Mass-balance constraints in
the Bulk Silicate Earth (BSE) tend instead to anti-correlate the radiogenic
element abundances in complementary reservoirs. Experimental geo-neutrino
observables may be further (anti)correlated by instrumental effects. In this
context, we propose a systematic approach to covariance matrices, based on the
fact that all the relevant geo-neutrino observables and constraints can be
expressed as linear functions of the U, Th and K abundances in the Earth's
reservoirs (with relatively well-known coefficients). We briefly discuss here
the construction of a tentative "geo-neutrino source model" (GNSM) for the U,
Th, and K abundances in the main Earth reservoirs, based on selected
geophysical and geochemical data and models (when available), on plausible
hypotheses (when possible), and admittedly on arbitrary assumptions (when
unavoidable). We use then the GNSM to make predictions about several
experiments ("forward approach"), and to show how future data can constrain - a
posteriori - the error matrix of the model itself ("backward approach"). The
method may provide a useful statistical framework for evaluating the impact and
the global consistency of prospective geo-neutrino measurements and Earth
models.Comment: 17 pages, including 4 figures. To appear on "Earth, Moon, and
Planets," Special Issue on "Neutrino Geophysics," Proceedings of Neutrino
Science 2005 (Honolulu, Hawaii, Dec. 2005
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