The Ursinus Weekly, November 23, 1977

Ursinus News in Brief: U.S.G.A. threatens boycott petition; Cafeteria dinner affirmed; Jessup announces computer courses; Williamson nominates two; Four elected to task force; Ursinus appliance team • Vandalism to exceed \u2776 totals: President\u27s dining room vandalized • U.C. unaware of breakout: How safe is Ursinus? • Enrollments decrease • Five call for U.S.G.A. action • Comment • Letters to the editor • Movie attack: MacArthur • A view of Wismer • Burns debuts as deity • Sex and drugs • Medical credentials • Opinion: S.F.A.R.C. • Grizzly Gridiron closes at 2-7 • Women\u27s volleyball: Wrap-up • Soccer finale • 3 & 4 end season 9-1 • Varsity hockey • X-Country dominateshttps://digitalcommons.ursinus.edu/weekly/1077/thumbnail.jp

The Ursinus Weekly, November 23, 1977

Ursinus News in Brief: U.S.G.A. threatens boycott petition; Cafeteria dinner affirmed; Jessup announces computer courses; Williamson nominates two; Four elected to task force; Ursinus appliance team • Vandalism to exceed \u2776 totals: President\u27s dining room vandalized • U.C. unaware of breakout: How safe is Ursinus? • Enrollments decrease • Five call for U.S.G.A. action • Comment • Letters to the editor • Movie attack: MacArthur • A view of Wismer • Burns debuts as deity • Sex and drugs • Medical credentials • Opinion: S.F.A.R.C. • Grizzly Gridiron closes at 2-7 • Women\u27s volleyball: Wrap-up • Soccer finale • 3 & 4 end season 9-1 • Varsity hockey • X-Country dominateshttps://digitalcommons.ursinus.edu/weekly/1077/thumbnail.jp

Enhanced Maternal Origin of the 22q11.2 Deletion in Velocardiofacial and DiGeorge Syndromes

Velocardiofacial and DiGeorge syndromes, also known as 22q11.2 deletion syndrome (22q11DS), are congenital-anomaly disorders caused by a de novo hemizygous 22q11.2 deletion mediated by meiotic nonallelic homologous recombination events between low-copy repeats, also known as segmental duplications. Although previous studies exist, each was of small size, and it remains to be determined whether there are parent-of-origin biases for the de novo 22q11.2 deletion. To address this question, we genotyped a total of 389 DNA samples from 22q11DS-affected families. A total of 219 (56%) individuals with 22q11DS had maternal origin and 170 (44%) had paternal origin of the de novo deletion, which represents a statistically significant bias for maternal origin (p = 0.0151). Combined with many smaller, previous studies, 465 (57%) individuals had maternal origin and 345 (43%) had paternal origin, amounting to a ratio of 1.35 or a 35% increase in maternal compared to paternal origin (p = 0.000028). Among 1,892 probands with the de novo 22q11.2 deletion, the average maternal age at time of conception was 29.5, and this is similar to data for the general population in individual countries. Of interest, the female recombination rate in the 22q11.2 region was about 1.6–1.7 times greater than that for males, suggesting that for this region in the genome, enhanced meiotic recombination rates, as well as other as-of-yet undefined 22q11.2-specific features, could be responsible for the observed excess in maternal origin

Barriers to antiretroviral therapy adherence in rural Mozambique

<p>Abstract</p> <p>Background</p> <p>HIV is treated as a chronic disease, but high lost-to-follow-up rates and poor adherence to medication result in higher mortality, morbidity, and viral mutation. Within 18 clinical sites in rural Zambézia Province, Mozambique, patient adherence to antiretroviral therapy has been sub-optimal.</p> <p>Methods</p> <p>To better understand barriers to adherence, we conducted 18 community and clinic focus groups in six rural districts. We interviewed 76 women and 88 men, of whom 124 were community participants (CP; 60 women, 64 men) and 40 were health care workers (HCW; 16 women, 24 men) who provide care for those living with HIV.</p> <p>Results</p> <p>While there was some consensus, both CP and HCW provided complementary insights. CP focus groups noted a lack of confidentiality and poor treatment by hospital staff (42% CP vs. 0% HCW), doubt as to the benefits of antiretroviral therapy (75% CP vs. 0% HCW), and sharing medications with family members (66% CP vs. 0%HCW). Men expressed a greater concern about poor treatment by HCW than women (83% men vs. 0% women). Health care workers blamed patient preference for traditional medicine (42% CP vs. 100% HCW) and the side effects of medication for poor adherence (8% CP vs. 83% CHW).</p> <p>Conclusions</p> <p>Perspectives of CP and HCW likely reflect differing sociocultural and educational backgrounds. Health care workers must understand community perspectives on causes of suboptimal adherence as a first step toward effective intervention.</p

Accuracy of Polar S410 heart rate monitor to estimate energy cost of exercise

Many studies have revealed shared music–language processing resources by finding an influence of music harmony manipulations on concurrent language processing. However, the nature of the shared resources has remained ambiguous. They have been argued to be syntax specific and thus due to shared syntactic integration resources. An alternative view regards them as related to general attention and, thus, not specific to syntax. The present experiments evaluated these accounts by investigating the influence of language on music. Participants were asked to provide closure judgements on harmonic sequences in order to assess the appropriateness of sequence endings. At the same time participants read syntactic garden-path sentences. Closure judgements revealed a change in harmonic processing as the result of reading a syntactically challenging word. We found no influence of an arithmetic control manipulation (experiment 1) or semantic garden-path sentences (experiment 2). Our results provide behavioural evidence for a specific influence of linguistic syntax processing on musical harmony judgements. A closer look reveals that the shared resources appear to be needed to hold a harmonic key online in some form of syntactic working memory or unification workspace related to the integration of chords and words. Overall, our results support the syntax specificity of shared music–language processing resources

BCOHTA 97:3C

This paper takes a critical approach to health technology assessment. Such an approach makes central the social, economic and political contexts in which health technologies are embedded. The task of this paper is to make explicit the hidden assumptions about aging women's bodies that drive the use of BMD testing. Primarily, it challenges the medical model of the aging female body as a diseased body, and questions the use of marketing strategies which create and capitalize on women's fear of aging. Finally, the paper raises questions about the ethical implications of proliferating technologies for economic and political motives at the expense of women's own needs and interests.Family Practice, Department ofMedicine, Faculty ofPopulation and Public Health (SPPH), School ofUnreviewedFacultyResearche