Magnetotransport in two-dimensional electron gas at large filling factors

We derive the quantum Boltzmann equation for the two-dimensional electron gas in a magnetic field such that the filling factor $\nu \gg 1$. This equation describes all of the effects of the external fields on the impurity collision integral including Shubnikov-de Haas oscillations, smooth part of the magnetoresistance, and non-linear transport. Furthemore, we obtain quantitative results for the effect of the external microwave radiation on the linear and non-linear $dc$ transport in the system. Our findings are relevant for the description of the oscillating resistivity discovered by Zudov {\em et al.}, zero-resistance state discovered by Mani {\em et al.} and Zudov {\em et al.}, and for the microscopic justification of the model of Andreev {\em et al.}. We also present semiclassical picture for the qualitative consideration of the effects of the applied field on the collision integral.Comment: 28 pages, 19 figures; The discussion of the role of the effect of the microwave field on the distribution function is revised (see also cond-mat/0310668). Accepted in Phys. Rev.

ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries

This review summarizes the last decade of work by the ENIGMA (Enhancing NeuroImaging Genetics through Meta Analysis) Consortium, a global alliance of over 1400 scientists across 43 countries, studying the human brain in health and disease. Building on large-scale genetic studies that discovered the first robustly replicated genetic loci associated with brain metrics, ENIGMA has diversified into over 50 working groups (WGs), pooling worldwide data and expertise to answer fundamental questions in neuroscience, psychiatry, neurology, and genetics. Most ENIGMA WGs focus on specific psychiatric and neurological conditions, other WGs study normal variation due to sex and gender differences, or development and aging; still other WGs develop methodological pipelines and tools to facilitate harmonized analyses of "big data" (i.e., genetic and epigenetic data, multimodal MRI, and electroencephalography data). These international efforts have yielded the largest neuroimaging studies to date in schizophrenia, bipolar disorder, major depressive disorder, post-traumatic stress disorder, substance use disorders, obsessive-compulsive disorder, attention-deficit/hyperactivity disorder, autism spectrum disorders, epilepsy, and 22q11.2 deletion syndrome. More recent ENIGMA WGs have formed to study anxiety disorders, suicidal thoughts and behavior, sleep and insomnia, eating disorders, irritability, brain injury, antisocial personality and conduct disorder, and dissociative identity disorder. Here, we summarize the first decade of ENIGMA's activities and ongoing projects, and describe the successes and challenges encountered along the way. We highlight the advantages of collaborative large-scale coordinated data analyses for testing reproducibility and robustness of findings, offering the opportunity to identify brain systems involved in clinical syndromes across diverse samples and associated genetic, environmental, demographic, cognitive, and psychosocial factors

The Annapolis Accords on the use of toxicology in decision-making. Annapolis Center Workshop Report.

The science of toxicology plays an important role in identifying safe conditions of use or exposure for many different kinds of environmental agents. The use of toxicologic information in risk assessment requires careful analysis, evaluation of data, and scientific judgment. These Annapolis Accords are intended to guide appropriate use in risk assessment of the scientific information from toxicology. We believe that application of these principles will improve the scientific credibility of risk assessment and the quality of decisions aimed at reducing and eliminating risks to human health and the environment