3 research outputs found
A convenient and eco-friendly one-pot synthesis of 3-triazolyl-2-iminochromenes and investigation of their antioxidant properties
A simple, green and efficient procedure for the synthesis of highly functionalized 3-triazolyl-2-iminochromenes by using a one-pot three component reaction of 2-azido acetonitrile, phenylacetylene and salicylaldehyde in water using CuI/K2CO3 is described. The present protocol offers advantages like high atom economy, simple methodology, shorter reaction time, easy product isolation, no chromatographic purification and avoidance of environmentally hazardous solvents. Compounds 4a-d, 4g-h and 6a-b have been investigated for antioxidant activity. Compound 4c is found to be the most active among the series showing high reducing power and free radical scavenging activity
Green and rapid synthesis of spiro[indoline-3,4’-pyrano[2,3-c]pyrazoles] in water: A practical method for large-scale synthesis
1049-1055Medicinally useful and structurally complex spiro[indoline-3,4’-pyrano[2,3-c]pyrazole] derivatives have been synthesized by one-pot three component reaction in water at room temperature with high atom economy in a short reaction time. The current report offers an environmentally benign protocol for obtaining the desired product in good yield and exclusion of conventional purification processes
A convenient and eco-friendly one-pot synthesis of 3-triazolyl-2-iminochromenes and investigation of their antioxidant properties
943-950A simple, green and efficient procedure for the synthesis of highly functionalized 3-triazolyl-2-iminochromenes by
using a one-pot three component reaction of 2-azido acetonitrile, phenylacetylene and salicylaldehyde in water using
CuI/K2CO3 is described. The present protocol offers advantages like high atom economy, simple methodology, shorter
reaction time, easy product isolation, no chromatographic purification and avoidance of environmentally hazardous solvents.
Compounds 4a-d, 4g-h and 6a-b have been investigated for antioxidant activity. Compound 4c is found to be the most
active among the series showing high reducing power and free radical scavenging activity