Green and rapid synthesis of spiro[indoline-3,4’-pyrano[2,3-c]pyrazoles] in water: A practical method for large-scale synthesis

Abstract

1049-1055Medicinally useful and structurally complex spiro[indoline-3,4’-pyrano[2,3-c]pyrazole] derivatives have been synthesized by one-pot three component reaction in water at room temperature with high atom economy in a  short reaction time. The current report offers an environmentally benign protocol for obtaining the desired product in good yield and exclusion of conventional purification processes

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