Mass flow rate of fine and cohesive powders under differential air pressure

The file attached to this record is the author's final peer reviewed version.Air-powder interactions are of practical importance in the production of pharmaceuticals, food and high value added chemicals manufactured using powders. For examples, air-powder effects enable consistent and effective dosing of fine cohesive powders into dies on high productivity rotary presses due to the suction fill effect. A purpose built experimental testing rig was developed and calibrated in order to develop a basic understanding of effect of air pressure on the mass flow rate of fine and cohesive powders. The powder materials were selected to enable the study of the effect of particle properties, such as size and density, and processing conditions such as differential air pressure, on the mass flow rate of powders. The models available in the literature developed for coarse free flowing sands under differential pressure were found inadequate to describe the experimental observations and to predict the flow behaviour of fine and cohesive powders. A new powder flow model was developed using established dimensional analysis methods based on the experimental data. The proposed model includes terms that account for the effect of differential pressure and reduces to the classic Beverloo model in absence of differential pressure. The models was validated and can be used for formulation and process design for flow regimes where air-powder interactions are important

Powder die filling under gravity and suction fill mechanisms

The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.In pharmaceutical tablet manufacturing, the powder formulation is filled into a die and compacted into a tablet using rigid punches. Die fill is important because it limits the productivity of tablet presses and determines key quality attributes of tablets including weight and content uniformity. Die fill occurs due to gravity and suction fill mechanisms. A model linear shoe-die filling system has been instrumented with pressure measurement devices for detailed characterisation of air pressure evolution as the powder mass is delivered in the die. Systematic experiments were carried out using a range of microcrystalline cellulose powders to explore the role of powder properties (such as particle size and bulk density) and operating parameters (such as shoe and die geometry, shoe and suction punch kinematics and powder filling level) on powder delivery. Existing models were found inadequate to describe the mass flow rate of powders under a diversity of gravity and suction filling conditions. The pressure measurements enabled the development of a new die fill model using the Buckingham Π theorem. The model includes separate terms for the contribution of the mass of powder delivered under gravity and suction fill mechanisms. The experimental procedures required to extract model parameters are described. The model is applicable to the handling and dosing of fine and cohesive powders where small differences in air pressure have a significant impact on the powder flow process. The practical application of the model for predicting die filling behaviour in a high-speed rotary tablet press is demonstrated by assuming operating conditions of a typical rotary tablet press. This approach can be adapted to assist formulation design and process development for operations involving handling and dosing of fine and cohesive powder

Vacuum assisted flow initiation in arching powders

The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.The discharge of powders from hoppers usually takes place in open atmosphere. However, in powder pressing industries (e.g. manufacturing of pharmaceutical tablets, detergents, ceramics, powder metallurgy etc.) there are handling operations where powders are filled into closed cavities such as dies. During this process the air pressure is increased as powder is delivered into the die. At the same time typical tablet production equipment creates a suction effect. A critical orifice measurement apparatus was developed to study powder flow initiation from an arching state into an enclosure where the air pressure is reduced. It was shown that a very small reduction of pressure changed the critical orifice diameter significantly. Dimensional analysis was carried out to relate powder properties (particle size and density) and processing parameters (geometry of the system and differential pressure necessary to break the arch). A relationship was developed to calculate the pressure difference necessary to initiate powder flow. The relationship has two empirical parameters which are calibrated by performing simple experiments using the testing rig developed