La Salud Mental en los reconocimientos escolares.

El presente estudio analiza el abordaje de. los temas de salud mental en los denominados «reconocimientos escolares». Estos pueden ser considerados como unos instrumentos de marcado carácter preventivo (prevención secundaria) dentro de la sanidad escolar, parcela importante de la salud pública. Bajo este prisma, los límites de nuestro trabajo están en señalar la metodología para ese abordaje, así como analizar los resultados que con ella se obtienen

Lipase active site covalent anchoring of Rh(NHC) catalysts: Towards chemoselective artificial metalloenzymes

A Rh(NHC) phosphonate complex reacts with the lipases cutinase and Candida antarctica lipase B resulting in the first (soluble) artificial metalloenzymes formed by covalent active site-directed hybridization. When compared to unsupported complexes, these new robust hybrids show enhanced chemoselectivity in the (competitive) hydrogenation of olefins over ketones. This journal i

Synthesis of air‐stable, odorless thiophenol surrogates via Ni‐Catalyzed C−S cross‐coupling

Thiophenols are versatile synthetic intermediates whose practical appeal is marred by their air sensitivity, toxicity and extreme malodor. Herein we report an efficient catalytic method for the preparation of S-aryl isothiouronium salts, and demonstrate that these air-stable, odorless solids serve as user-friendly sources of thiophenols in synthesis. Diverse isothiouronium salts featuring synthetically useful functionality are readily accessible via nickelcatalyzed C-S cross-coupling of (hetero)aryl iodides and thiourea. Convenient, chromatography-free isolation of these salts is achieved via precipitation, allowing the methodology to be translated directly to large scales. Thiophenols are liberated from the corresponding isothiouronium salts upon treatment with a weak base, enabling an in situ release / S-functionalization strategy that entirely negates the need to isolate, purify or manipulate these noxious reagent

Agonía, traición, huida. [RECENSIÓN]

Rodríguez Jiménez, José Luis, Agonía, traición, huida. El final del Sahara español, Barcelona, Crítica, 2015, 676 p. ISBN:9788498928754. 23,65

Agonía, traición, huida. [RECENSIÓN]

Rodríguez Jiménez, José Luis, Agonía, traición, huida. El final del Sahara español, Barcelona, Crítica, 2015, 676 p. ISBN:9788498928754. 23,65

Effects of thinning and pruning on stem and crown characteristics of radiata pine (Pinus radiata D. Don)

Simultaneous applications of thinning and pruning are common silvicultural practices in radiata pine (Pinus radiata) forest plantations. Their separate effects on tree growth and wood quality have been well studied, but their combined effect is not clear yet. The aim of this study is to identify how thinning and pruning together affect the stem structure and properties of the pruned but also the unpruned section of the trees (the portions formed immediately after the application of these management efforts). The effects of pruning and thinning on the number of growth units per year, internode length, number of branches, and branch diameters was analyzed in managed and unmanaged stands of radiata pine grown in Chile. When used jointly, these practices generated larger individual tree volumes (135% more) and clear wood in the pruned logs; however, they also reduced the sawn wood quality of the unpruned stem section for some years after the silvicultural interventions. The managed trees showed more growth units per annual shoot and shorter internodes, thus generating more knotty wood. Moreover, managed trees showed more taper. As trees of the managed stand restore the foliar biomass lost due to pruning, managed and unmanaged stands approach the same level of canopy closure, and differences minimize

Ring-Closing and Cross-Metathesis with Artificial Metalloenzymes Created by Covalent Active Site-Directed Hybridization of a Lipase

A series of Grubbs-type catalysts that contain lipase-inhibiting phosphoester functionalities have been synthesized and reacted with the lipase cutinase, which leads to artificial metalloenzymes for olefin metathesis. The resulting hybrids comprise the organometallic fragment that is covalently bound to the active amino acid residue of the enzyme host in an orthogonal orientation. Differences in reactivity as well as accessibility of the active site by the functionalized inhibitor became evident through variation of the anchoring motif and substituents on the N-heterocyclic carbene ligand. Such observations led to the design of a hybrid that is active in the ring-closing metathesis and the cross-metathesis of N,N-diallyl-p-toluenesulfonamide and allylbenzene, respectively, the latter being the first example of its kind in the field of artificial metalloenzymes