Designing Computationally Creative Musical Performance Systems

This is work in progress where we outline a design process for a computationally creative musical performance system using the Creative Systems Framework (CSF). The proposed system is intended to produce virtuosic interpretations, and subsequent synthesized renderings of these interpretations with a physical model of a bass guitar, using case-based reasoning and reflection. We introduce our interpretations of virtuosity and musical performance, outline the suitability of case-based reasoning in computationally creative systems and introduce notions of computational creativity and the CSF. We design our system by formalising the components of the CSF and briefly outline a potential implementation. In doing so, we demonstrate how the CSF can be used as a tool to aid in designing computationally creative musical performance systems

Influence of Music on Perceived Emotions in Film

Film music plays a core role in film production and reception as it not only contributes to the film aesthetics and creativity, but it also affects viewers' experience and enjoyment. Film music composers often aim to serve the film narrative, immerse viewers into the setting and story, convey clues, and importantly, act on their emotions. Yet, how film music influences viewers is still misunderstood. We conducted a perceptual study to analyse the impact of music on the perception of emotions in film. We developed an online interface for time-based emotion annotation of audio/video media clips based on the Valence/Arousal (VA) two-dimensional model. Participants reported their perceived emotions over time in the VA space for three media conditions: film scene presented without sound (video only), film music presented without video (audio only), and film scene with accompanying music and sound effects (both video and audio modalities). 16 film clips were selected covering four clips for each of four genres (action & drama, romance, comedy, and horror). 38 participants completed the study (12 females and 26 males from many countries, average age: 28.9). Density scatter plots are used to visualise the spread of emotion ratings in the VA space and differences across media conditions and film clips. Results from linear mixed effect models show significant effects of the audiovisual media condition and film genre on VA ratings, in line with previous results by Parke et al. [1]. Perceived VA ratings across media conditions follow an almost linear relationship with an increase in strength in the following order: film alone, film with music/sound, music alone. We illustrate this effect by plotting the VA rating centre of mass across conditions. VA ratings for the film-alone condition are closer to the origin of the space compared to the two other media conditions, indicating that the inclusion of music yields stronger emotions (higher VA ratings). Certain individual factors (musical ability, familiarity, preference) also seem to impact the perception of arousal and valence while viewing films. Our online emotion annotation interface was on overall well received and suggestions to improve the display of reference emotion tags are discussed

Detection of explosives vapours on quartz crystal microbalances: generation of very low-concentrated vapours for sensors calibration

AbstractA controlled vapours generator of explosives compounds has been evaluated for delivering low-concentrated vapours in order to determine the threshold of quartz crystal microbalances based chemical gas sensors

Audio Features Affected by Music Expressiveness

Within a Music Information Retrieval perspective, the goal of the study presented here is to investigate the impact on sound features of the musician's affective intention, namely when trying to intentionally convey emotional contents via expressiveness. A preliminary experiment has been performed involving $10$ tuba players. The recordings have been analysed by extracting a variety of features, which have been subsequently evaluated by combining both classic and machine learning statistical techniques. Results are reported and discussed.Comment: Submitted to ACM SIGIR Conference on Research and Development in Information Retrieval (SIGIR 2016), Pisa, Italy, July 17-21, 201

Evaluation of the performances of a single-use duodenoscope: Prospective multi-center national study

Objectives: A single-use duodenoscope (SUD) has been recently developed to overcome issues with endoscopic retrograde cholangiopancreatography (ERCP)-related cross-infections. The aim was to evaluate SUD safety and performance in a prospective multi-centre study. Methods: All consecutive patients undergoing ERCP in six French centers were prospectively enrolled. All procedures were performed with the SUD; in case of ERCP failure, operators switched to a reusable duodenoscope. Study outcomes were the successful completion of the procedure with SUD, safety and operators’ satisfaction based on a VAS 0–10 and on 22 qualitative items. The study protocol was approved by French authorities and registered (ID-RCB: 2020-A00346-33). External companies collected the database and performed statistical analysis. Results: Sixty patients (34 females, median age 65.5 years old) were enrolled. Main indications were bile duct stones (41.7%) and malignant biliary obstruction (26.7%). Most ERCP were considered ASGE grade 2 (58.3%) or 3 (35.0%). Fifty-seven (95.0%) procedures were completed using the SUD. Failures were unrelated to SUD (one duodenal stricture, one ampullary infiltration, and one tight biliary stricture) and could not be completed with reusable duodenoscopes. Median operators’ satisfaction was 9 (7–9). Qualitative assessments were considered clinically satisfactory in a median of 100% of items and comparable to a reusable duodenoscope in 97.9% of items. Three patients (5%) reported an adverse event. None was SUD-related. Conclusions: The use of a SUD allows ERCP to be performed with an optimal successful rate. Our data show that SUD could be used for several ERCP indications and levels of complexity

Learning Combinations of Multiple Feature Representations for Music Emotion Prediction

Music consists of several structures and patterns evolving through time which greatly influences the human decoding of higher-level cognitive aspects of music like the emotions expressed in music. For tasks, such as genre, tag and emotion recognition, these structures have often been identified and used as individual and non-temporal features and representations. In this work, we address the hypothesis whether using multiple temporal and non-temporal representations of different features is beneficial for modeling music structure with the aim to predict the emotions expressed in music. We test this hypothesis by representing temporal and non-temporal structures using generative models of multiple audio features. The representations are used in a discriminative setting via the Product Probability Kernel and the Gaussian Process model enabling Multiple Kernel Learning, finding optimized combinations of both features and temporal/ non-temporal representations. We show the increased predictive performance using the combination of different features and representations along with the great interpretive prospects of this approach

Timbre from Sound Synthesis and High-level Control Perspectives

International audienceExploring the many surprising facets of timbre through sound manipulations has been a common practice among composers and instrument makers of all times. The digital era radically changed the approach to sounds thanks to the unlimited possibilities offered by computers that made it possible to investigate sounds without physical constraints. In this chapter we describe investigations on timbre based on the analysis by synthesis approach that consists in using digital synthesis algorithms to reproduce sounds and further modify the parameters of the algorithms to investigate their perceptual relevance. In the first part of the chapter timbre is investigated in a musical context. An examination of the sound quality of different wood species for xylophone making is first presented. Then the influence of instrumental control on timbre is described in the case of clarinet and cello performances. In the second part of the chapter, we mainly focus on the identification of sound morphologies, so called invariant sound structures responsible for the evocations induced by environmental sounds by relating basic signal descriptors and timbre descriptors to evocations in the case of car door noises, motor noises, solid objects, and their interactions

High APACHE II score and long length of bowel resection impair the outcomes in patients with necrotic bowel induced hepatic portal venous gas

<p>Abstract</p> <p>Background</p> <p>Hepatic portal venous gas (HPVG) is a rare but potentially lethal condition, especially when it results from intestinal ischemia. Since the literatures regarding the prognostic factors of HPVG are still scarce, we aimed to investigate the risk factor of perioperative mortality in this study.</p> <p>Methods</p> <p>We analyzed data for patients with intestinal ischemia induced HPVG by chart review in our hospital between 2000 and 2007. Factors associated with perioperative mortality were specifically analyzed.</p> <p>Results</p> <p>There were 22 consecutive patients receiving definite bowel resection. 13 cases (59.1%) died after surgical intervention. When analyzing the mortality in patients after bowel resections, high Acute Physiology And Chronic health Evaluation (APACHE) II score (<it>p < 0.01</it>) and longer length of bowel resection (<it>p </it>= 0.047) were significantly associated with mortality in univariate analyses. The complication rate was 66.7% in alive patients after definite bowel resection.</p> <p>Conclusions</p> <p>Bowel resection was the only potential life-saving therapy for patients with mesenteric ischemia induced HPVG. High APACHE II score and severity of underlying necrotic bowel determined the results in patients after bowel resection.</p

The reg4 Gene, Amplified in the Early Stages of Pancreatic Cancer Development, Is a Promising Therapeutic Target

BACKGROUND: The aim of our work was to identify the genes specifically altered in pancreatic adenocarcinoma and especially those that are altered early in cancer development. METHODOLOGY/PRINCIPAL FINDINGS: Gene copy number was systematically assessed with an ultra-high resolution CGH oligonucleotide microarray in DNA from samples of pancreatic cancer. Several new cancer-associated variations were observed. In this work we focused on one of them, involving the reg4 gene. Gene copy number gain of the reg4 gene was confirmed by qPCR in 14 cancer samples. It was also found with increased copy number in most PanIN3 samples. The relationship betweena gain in reg4 gene copy number and cancer development was investigated on the human pancreatic cancer cell line Mia-PaCa2 xenografted under the skin of nude mice. When cells were transfected with a vector allowing reg4 expression, they generated tumors almost twice larger in size. In addition, these tumors were more resistant to gemcitabine treatment than control tumors. Interestingly, weekly intraperitoneal administration of a monoclonal antibody to reg4 halved the size of tumors generated by Mia-PaCa2 cells, suggesting that the antibody interfered with a paracrine/autocrine mechanism involving reg4 and stimulating cancer progression. The addition of gemcitabine resulted in further reduction, tumors becoming 5 times smaller than control. Exposure to reg4 antibody resulted in a significant decrease in intra-tumor levels of pAkt, Bcl-xL, Bcl-2, survivin and cyclin D1. CONCLUSIONS/SIGNIFICANCE: It was concluded that adjuvant therapies targeting reg4 could improve the standard treatment of pancreatic cancer with gemcitabine