What impressions do users have after a ride in an automated shuttle? An interview study

In the future, automated shuttles may provide on-demand transport and serve as feeders to public transport systems. However, automated shuttles will only become widely used if they are accepted by the public. This paper presents results of an interview study with 30 users of an automated shuttle on the EUREF (Europäisches Energieforum) campus in Berlin-Schöneberg to obtain in-depth understanding of the acceptance of automated shuttles as feeders to public transport systems. From the interviews, we identified 340 quotes, which were classified into six categories: (1) expectations about the capabilities of the automated shuttle (10% of quotes), (2) evaluation of the shuttle performance (10%), (3) service quality (34%), (4) risk and benefit perception (15%), (5) travel purpose (25%), and (6) trust (6%). The quotes indicated that respondents had idealized expectations about the technological capabilities of the automated shuttle, which may have been fostered by the media. Respondents were positive about the idea of using automated shuttles as feeders to public transport systems but did not believe that the shuttle will allow them to engage in cognitively demanding activities such as working. Furthermore, 20% of respondents indicated to prefer supervision of shuttles via an external control room or steward on board over unsupervised automation. In conclusion, even though the current automated shuttle did not live up to the respondents’ expectations, respondents still perceived automated shuttles as a viable option for feeders to public transport systems.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Transport and PlanningHuman-Robot InteractionIntelligent VehiclesTransport and Plannin

A perspective on the role of class III semaphorin signaling in central nervous system trauma.

Traumatic injury of the central nervous system (CNS) has severe impact on the patients' quality of life and initiates many molecular and cellular changes at the site of insult. Traumatic CNS injury results in direct damage of the axons of CNS neurons, loss of myelin sheaths, destruction of the surrounding vascular architecture and initiation of an immune response. Class III semaphorins (SEMA3s) are present in the neural scar and influence a wide range of molecules and cell types in and surrounding the injured tissue. SEMA3s and their receptors, neuropilins (NRPs) and plexins (PLXNs) were initially studied because of their involvement in repulsive axon guidance. To date, SEMA3 signaling is recognized to be of crucial importance for re-vascularization, the immune response and remyelination. The purpose of this review is to summarize and discuss how SEMA3s modulate these processes that are all crucial components of the tissue response to injury. Most of the functions for SEMA3s are achieved through their binding partners NRPs, which are also co-receptors for a variety of other molecules implicated in the above processes. The most notable ligands are members of the vascular endothelial growth factor (VEGF) family and the transforming growth factor family. Therefore, a second aim is to highlight the overlapping or competing signaling pathways that are mediated through NRPs in the same processes. In conclusion, we show that the role of SEMA3s goes beyond inhibiting axonal regeneration, since they are also critical modulators of re-vascularization, the immune response and re-myelination