Pit Stop

Electric cars are rapidly gaining popularity across the United States because they are environmentally friendly. The problem is that the United States does not have enough infrastructure to support the number of electric cars expected to be purchased in the next decade. This project strove to fix that problem by converting an old gas station to an electric car charging station that doubled as a roadside attraction. Pit Stop functions as a charging station, a restaurant, and an exercise/play area for families to stretch their legs between drives. All the parking spots come equipped with an electric car charging unit, so there will always be space available. Located on top of the canopy that covers the cars is a classic American grill that the whole family can enjoy entitled The Grill. The restaurant features standard tables for families in a rush, or if the family has extra time, they can have their food grilled in front of them. On the backside of the lot located away from the street traffic is exercise space for adults and a play area for kids. Since this project caters to a family on a road trip, including space to burn off energy before getting back in the car is vital. The structure of the building is a combination of 2 systems. The first is a timer beam system that supports the floor from below, and the second is a steel cable system that pulls up from above. These two systems together keep the canopy and restaurant in tension and stable

Globotriaosylceramide is correlated with oxidative stress and inflammation in Fabry patients treated with enzyme replacement therapy

AbstractFabry disease is an X-linked inborn error of glycosphingolipid catabolism due to deficient activity of α-galactosidase A that leads to accumulation of the enzyme substrates, mainly globotriaosylceramide (Gb3), in body fluids and lysosomes of many cell types. Some pathophysiology hypotheses are intimately linked to reactive species production and inflammation, but until this moment there is no in vivo study about it. Hence, the aim of this study was to investigate oxidative stress parameters, pro-inflammatory cytokines and Gb3 levels in Fabry patients under treatment with enzyme replacement therapy (ERT) and finally to establish a possible relation between them. We analyzed urine and blood samples of patients under ERT (n=14) and healthy age-matched controls (n=14). Patients presented decreased levels of antioxidant defenses, assessed by reduced glutathione (GSH), glutathione peroxidase (GPx) activity and increased superoxide dismutase/catalase (SOD/CAT) ratio in erythrocytes. Concerning to the damage to biomolecules (lipids and proteins), we found that plasma levels of malondialdehyde (MDA) and protein carbonyl groups and di-tyrosine (di-Tyr) in urine were increased in patients. The pro-inflammatory cytokines IL-6 and TNF-α were also increased in patients. Urinary Gb3 levels were positively correlated with the plasma levels of IL-6, carbonyl groups and MDA. IL-6 levels were directly correlated with di-Tyr and inversely correlated with GPx activity. This data suggest that pro-inflammatory and pro-oxidant states occur, are correlated and seem to be induced by Gb3 in Fabry patients

CUIDANDO DE QUEM CUIDA: COMPARTILHANDO E CONSTRUINDO SABERES E JUNTO À CUIDADORES DE PESSOAS COM DEFICIÊNCIA

UNIVERSIDADE FEDERAL DE CIÊNCIAS DA SAÚDE DE PORTO ALEGR

Tópicos de fisiologia aliados à extensão universitária como ferramenta para promover o bem-estar de cuidadoras de PcD

Familiares cuidadores de pessoas com deficiência (PcD) abdicam muitas vezes de seu bem-estar em função dos cuidados necessários de seu ente cuidado. Assim, o objetivo deste estudo foi trabalhar a Fisiologia do sono e do sistema digestório com as cuidadoras de PcD que fazem acompanhamento em Centro de Reabilitação de Porto Alegre ligadas ao projeto de extensão universitária denominado “Apoiando e educando as famílias de pessoa com deficiência”, estimulando-se o bem-estar dessas mulheres. Como metodologias para o estudo da Fisiologia junto às cuidadoras foram utilizadas rodas de conversa, a Escala de Sonolência de EPWORTH, moldes anatômicos do sistema digestório e questionário sobre constipação intestinal em dois encontros com duração de 90 minutos cada um. Participaram das atividades relativas à Fisiologia do sono 9 cuidadoras e observou-se que 66,6% delas deveriam cuidar mais de seu sono ou apresentavam sono inadequado. Quanto a Fisiologia do sistema digestório, 11 cuidadoras participaram das atividades e 20% foram consideradas constipadas. O estudo sobre a Fisiologia do sono e do sistema digestório fez com que as cuidadoras pudessem refletir sobre o autocuidado em relação a estes aspectos e oportunizou que as extensionistas colocassem em prática o conhecimento da Universidade. Palavras-chave: Extensão; Educação em saúde; Rede de apoio; Sono; Sistema digestório   Topics of physiology in promoting the well-being of people with disabilities caregivers Abstract: Family caregivers of people with disabilities (PwD) often abdicate their well-being due to the necessary care of their entity. Thus, this study aimed to work on sleep and digestive system physiology with PwD caregivers whom follow-up on the Rehabilitation Center of Porto Alegre (Brazil) linked to the university extension project called "Supporting and educating families of people with disabilities," stimulating the well-being of these women. As methodologies for studying physiology with caregivers, we used conversation wheels, the EPWORTH Sleepiness Scale, anatomical molds of the digestive system, and intestinal constipation questionnaire in two 90-minute meetings. Nine caregivers participated in sleep physiology activities, and it was observed that 66.6% of respondents should take better care of their sleep or had an inadequate sleep. Regarding the physiology of the digestive system, 11 caregivers participated in the activities, and 20% were considered constipated. The study of sleep and digestive system physiology allowed caregivers to think about self-care, improving their well-being, and helped the extensionists to put the University's knowledge into practice. Keywords: Extension; Health education; Support network; Sleeping; Digestive syste

Multiplicadores de conhecimento: Papel das ações de extensão junto a cuidadores de pessoas com deficiência

Para que ocorra a extensão universitária é necessário elencar uma população-alvo para dirigirem-se as ações extensionistas. No entanto, estas ações tendem a se estender para além da comunidade, por ação de formação de multiplicadores de conhecimento na própria população atendida. O objetivo deste estudo é fazer um relato de experiência da contribuição de ações de extensão para além do público-alvo quando se trabalha temas relacionados à saúde como o uso de plantas e chás medicinais e a Hipertensão Arterial Sistêmica junto a cuidadores de Pessoas com Deficiência (PcD). Este projeto de extensão atuou junto a quinze cuidadoras de pessoas com deficiência a partir de temas sugeridos por elas. Na atividade sobre plantas e chás medicinais as metodologias utilizadas foram caixa de mitos e verdades, roda de conversa, jogo de bingo e distribuição de fôlderes. Para a atividade sobre hipertensão utilizou-se “tempestade de ideias”, aferição da pressão arterial e distribuição de fôlderes. Essas ações foram realizadas em 3 encontros entre março e maio de 2019. Como resultado, tivemos a participação de 11 a 16 cuidadoras (sendo uma participante ocasional) e 2 a 3 funcionárias da Instituição parceira nos encontros. Observou-se que as metodologias ativas empregadas foram importantes para o aprendizado e fixação dos conteúdos abordados segundo as falas das próprias cuidadoras. As ações possibilitaram que os saberes construídos fossem compartilhados com amigos e familiares das participantes, caracterizando a contribuição do projeto para formação de multiplicadores do conhecimento. Palavras-chave: Ensino; Disseminação de informação; Educação em saúde Knowledge multipliers: Role of extension actions with caregivers of people with disabilities Abstract: For the university extension to occur, it is necessary to establish a target population to which extension actions will be directed. However, these actions tend to spread beyond the community by forming knowledge multipliers in the served population. This study aimed to report the experience of the contribution of extension actions beyond the target audience when working on health-related topics such as the use of medicinal plants and teas and Systemic Arterial Hypertension with caregivers of People with Disabilities (PwD). This extension project worked with fifteen caregivers of PwD based on themes suggested by them. In the medicinal plants and teas activity, the methodologies used were the box of myths and truths, conversation wheel, bingo game, and distribution of folders. For the activity on hypertension, we used "brainstorm," blood pressure measurement, and distribution of folders. These actions were carried out in 3 meetings between March and May 2019. As a result, 11 to 16 caregivers (one casual) and 2 to 3 employees from the partner institution participate in the meetings. It was observed that the active methodologies used were important for learning and fixing the contents addressed, according to the words of the caregivers themselves. The actions allowed the caregivers to share what they learned, taking this knowledge to friends and family, as well as the employees of the partner institution who participated, characterizing the contribution of the project beyond the target audience. Keywords: Teaching; Information Dissemination; Health educatio

Estresse oxidativo em pacientes com diferentes formas clínicas de adrenoleucodistrofia ligada ao X

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Ácidos graxos de cadeia muito longa em pacientes com diferentes formas clínicas de adrenoleucodistrofia ligada ao X : o efeito do Óleo de Lorenzo

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