Atropine in mushrooms: therapeutic implications

No Abstrac

Studies in cholestrol metabolism

The biochemistry of the steroids is of unique interest; no other group of relatively simple substances plays so versatile a role in biology. On the one hand are many highly potent steroids occurring in minute quantities e.g. sex hormones, corticosteroids, the vitamins D and the cardiac glycosides. In sharp contrast are certain sterols, exemplified in the animal kingdom by cholesterol - familiar, abundant, easily determined, yet singularly obscure in their physiological significance. In some restricted fields the functions of cholesterol are known. It is a precursor of the adrenocortical hormones (perhaps not an obligatory one ), and is probably important in the biosynthesis of sex hormones too. Present in the skin is 7-dehydrocholesterol, converted to vitamins D by ultraviolet light. Cholesteryl esters are found in large quantities, together with sphingomyelin, in the myelin sheaths of nerve fibres, where these lipids may have an insulating function necessary at least for saltatory conduction

A New Synthesis of Early Medieval Brittonic History (Wales and the Britons 350–1064 by Thomas M. Charles-Edwards)

A review article on Thomas M. Charles-Edwards, Wales and the Britons 350–1064 (Oxford, 2013)

Kentucky Archaeology

Kentucky’s rich archaeological heritage spans thousands of years, and the Commonwealth remains fertile ground for study of the people who inhabited the midcontinent before, during, and after European settlement. This long-awaited volume brings together the most recent research on Kentucky’s prehistory and early history, presenting both an accurate descriptive and an authoritative interpretation of Kentucky’s past. The book is arranged chronologically—from the Ice Age to modern times, when issues of preservation and conservation have overtaken questions of identification and classification. For each time slice of Kentucky’s past, the contributors describe typical communities and settlement patterns, major changes from previous cultural periods, the nature of the economy and subsistence, artifacts, the general health and characteristics of the people, and regional cultural differences. Sites discussed include the Green River shell mounds, the Central Kentucky Adena mounds and enclosures, Eastern Kentucky rockshelters, the important Wickliffe site at the confluence of the Mississippi and Ohio rivers, Fort Ancient culture villages, and the fortified towns of the Mississippian period in Western Kentucky. The authors draw from a wealth of unpublished material and offer the detailed insights and perspectives of specialists who have focused much of their professional careers on the scientific investigation of Kentucky’s prehistory. The book’s many graphic elements—maps, artifact drawings, photographs, and village plans—combined with a straightforward and readable text, provide a format that will appeal to the general reader as well as to students and specialists in other fields who wish to learn more about Kentucky’s archaeology. R. Barry Lewis is associate professor of archaeology at the University of Illinois at Urbana-Champaign and a past president of the Illinois Archaeological survey. He has been actively involved in archaeological research in Kentucky since 1980. A valuable resource for researchers as well as an accessible account for the non-professional enthusiast. . . . An excellent way to enhance your travel through Kentucky and nearby states in search of archaeological attractions. Fortunately for professionals and the public alike, Kentucky has an exemplary record of preserving and protecting this rich heritage. Kentucky Archaeology is a product of such efforts. —American Archaeology Among the rarest of finds is a book about archaeology that is informative, well-written, clearly illustrated, and entertaining—one that opens a tremendous storehouse of archaeological knowledge, without crushing the reader under the mass of artifact descriptions. . . . The authors and editors of Kentucky Archaeology succeed in making the Commonwealth\u27s rich archaeological heritage accessible to the public. —North Carolina Historical Review A compelling and precise presentation of what is known about Kentucky\u27s past and the lifeways of the people who lived in what is now known as Kentucky. —Register of the Kentucky Historical Society With articles written by some of the nation’s, and Kentucky’s, leading archaeologists, Kentucky Archaeology is the definitive guide to the topic. —The Dirt Brothershttps://uknowledge.uky.edu/upk_archaeological_anthropology/1001/thumbnail.jp

St Mechyll of Anglesey, St Maughold of Man and St Malo of Brittany

A late-medieval Welsh poem in honour of the Anglesey saint Mechyll contains features drawn from two other cults, those of the Breton St Malo and the Manx St Maughold. This article surveys the evidence for the interpenetration of these three cults in medieval Man and Anglesey. It describes first the contents of the Welsh poem and the other evidence for the cult of Mechyll. It demonstrates that Mechyll was identified with Malo under his Latin name, Machutus, though the identification itself is unhistorical. The question of the name of Malo-Machutus, the spread of his cult and the hagiography associated with him are then surveyed. It is shown that St Maughold of Man was likewise associated with Machutus, and that much the same thing happened at the Scottish church of Lesmahagow, originally dedicated to St Féchín. The place of Maughold in the Lives of St Patrick is then discussed, confirming that Maughold of Man was the saint associated by Muirchú (c.700) with Patrick’s adversary Mac Cuill. The final question raised is the name of Maughold himself. Though it is unlikely that Maughold and Mechyll were really the same historical individual, the possibility is acknowledged

St Mechyll of Anglesey, St Maughold of Man and St Malo of Brittany

A late-medieval Welsh poem in honour of the Anglesey saint Mechyll contains features drawn from two other cults, those of the Breton St Malo and the Manx St Maughold. This article surveys the evidence for the interpenetration of these three cults in medieval Man and Anglesey. It describes first the contents of the Welsh poem and the other evidence for the cult of Mechyll. It demonstrates that Mechyll was identified with Malo under his Latin name, Machutus, though the identification itself is unhistorical. The question of the name of Malo-Machutus, the spread of his cult and the hagiography associated with him are then surveyed. It is shown that St Maughold of Man was likewise associated with Machutus, and that much the same thing happened at the Scottish church of Lesmahagow, originally dedicated to St Féchín. The place of Maughold in the Lives of St Patrick is then discussed, confirming that Maughold of Man was the saint associated by Muirchú (c.700) with Patrick’s adversary Mac Cuill. The final question raised is the name of Maughold himself. Though it is unlikely that Maughold and Mechyll were really the same historical individual, the possibility is acknowledged

Arthurian references in medieval Welsh poetry, c. 1100-c. 1540

A survey of references to characters and events with a connection to Arthur and the Arthurian story-world within the works of medieval Welsh poets. The specifically `Arthurian' poems are excluded as they are dealt with by another contributor in the volume. Instead, the poems examined here are praise poetry, love poetry, satire, prophecy and religious verse. The chapter explores the changing aspects of the Arthurian story-world to which medieval Welsh poets make reference. In the twelfth century, references indicate that the poets accessed a predominantly native Arthurian tradition, but were already being exposed to French Arthurian literature. French influence increased steadily over the centuries to become quite predominant, but some memory was retained of divergent and sometimes conflicting Welsh traditions of Arthur

Some Implications of a Non-Deterministic Model of Teacher Development

Since the 1950s, pre-service teachers and teacher educators have been caught in a quagmire of confusion as teacher education came to be held in increasingly poor repute. More recently, in Britain and Australia particularly, colleges and faculties of education took the major brunt of cuts in spending on education. Most of the old certainties - the certainty of a job at the end of one\u27s training; the certainty of the absorption model of teacher training characterised by the \u27give \u27em a bit of everything and turn \u27em loose\u27 philosophy; the certainty of tenure in a college lecturing position - vanished in a very brief period. Vocal students argued that teacher education was inadequate; academics challenged what they saw as weak content taught by sub-standard staff; some schools tended to treat teacher education as a bit of a nuisance, if not actually totally irrelevant; while employing authorities regarded it as blameworthy for not being more efficient in producing a more desirable product (Claydon and Lovegrove, 1972)

Efficient computation of steady, 3D water-wave patterns

Numerical methods for the computation of stationary free surfaces is the subject of much current research in computational engineering. The present report is directed towards free surfaces in maritime engineering. Of interest here are the long steady waves generated by ships, the gravity waves. In the present report an existing 2D iterative method for the computation of stationary gravity-wave solutions is extended to 3D, numerically investigated, and improved. The method employs the so-called quasi free-surface boudary condition. As test cases we cosider gravity-wave patterns due to pressure perturbations imposed at the free surface of a steady, uniform horizontal flow. The effects are studied of the distance of the imposed pressure distribution to the far-field boundary, the magnitude of the imposed pressure perturbation, and the mesh widths. In all experiments, our focus is on the convergence behavior of the free-surface iteration process

Shoring Up Shortfalls: Women, Retirement and the Growing GigSupp Economy

In recent years, high-profile Silicon Valley firms have engineered billion-dollar IPOs through developing online and app-based platforms that connect service providers and sellers with customers and process their payments (the “online platform economy”). Today, millions of Americans earn income using platforms developed by Uber, Etsy, and Airbnb; and research has identified the limitations of existing federal tax rules to facilitate tax compliance of these workers and considered the consequences of their failure to pay self-employment taxes. However, questions remain as to the changing demographics and motivations of online platform economy workers and their retirement income security. Titled, Shoring Up Shortfalls: Women, Retirement and the Growing Gig Economy, we propose to identify and analyze: (i) the existing demographic data on this workforce; (ii) their economic motivations and retirement income needs; and (iii) the federal tax, retirement policy, and financial literacy proposals that would enable the gig economy workforce to support itself in retirement