507 research outputs found
A Safe, Stable Place to Call Home Supports Young Children's Health in Arkansas
Families should be able to afford a roof over their heads and still have enough money to pay for food, utilities, and healthcare. Unfortunately, for many Arkansans, wages are not keeping up with housing costs. Presently, fair market rent for a two-bedroom apartment is 7.25/hour can afford. Children's HealthWatch research shows families are forced to sacrifice basic necessities when they confront the gap between the cost of housing and their ability to pay for it
Commissioning of the vacuum system of the KATRIN Main Spectrometer
The KATRIN experiment will probe the neutrino mass by measuring the β-electron energy spectrum near the endpoint of tritium β-decay. An integral energy analysis will be performed by an electro-static spectrometer (``Main Spectrometer''), an ultra-high vacuum vessel with a length of 23.2 m, a volume of 1240 m[superscript 3], and a complex inner electrode system with about 120 000 individual parts. The strong magnetic field that guides the β-electrons is provided by super-conducting solenoids at both ends of the spectrometer. Its influence on turbo-molecular pumps and vacuum gauges had to be considered. A system consisting of 6 turbo-molecular pumps and 3 km of non-evaporable getter strips has been deployed and was tested during the commissioning of the spectrometer. In this paper the configuration, the commissioning with bake-out at 300 °C, and the performance of this system are presented in detail. The vacuum system has to maintain a pressure in the 10[superscript −11] mbar range. It is demonstrated that the performance of the system is already close to these stringent functional requirements for the KATRIN experiment, which will start at the end of 2016.United States. Department of Energy (DE-FG02-97ER41020)United States. Department of Energy (DE-FG02-94ER40818)United States. Department of Energy (DE-SC0004036)United States. Department of Energy (DE-FG02-97ER41041)United States. Department of Energy (DE-FG02-97ER41033
Bifidobacterium breve with α-Linolenic Acid and Linoleic Acid Alters Fatty Acid Metabolism in the Maternal Separation Model of Irritable Bowel Syndrome
peer-reviewedThe aim of this study was to compare the impact of dietary supplementation with a Bifidobacterium breve strain together with linoleic acid & α-linolenic acid, for 7 weeks, on colonic sensitivity and fatty acid metabolism in rats. Maternally separated and non-maternally separated Sprague Dawley rats (n = 15) were orally gavaged with either B. breve DPC6330 (109 microorganisms/day) alone or in combination with 0.5% (w/w) linoleic acid & 0.5% (w/w) α-linolenic acid, daily for 7 weeks and compared with trehalose and bovine serum albumin. Tissue fatty acid composition was assessed by gas-liquid chromatography and visceral hypersensitivity was assessed by colorectal distension. Significant differences in the fatty acid profiles of the non-separated controls and maternally separated controls were observed for α-linolenic acid and arachidonic acid in the liver, oleic acid and eicosenoic acid (c11) in adipose tissue, and for palmitoleic acid and docosahexaenoic acid in serum (p<0.05). Administration of B. breve DPC6330 to MS rats significantly increased palmitoleic acid, arachidonic acid and docosahexaenoic acid in the liver, eicosenoic acid (c11) in adipose tissue and palmitoleic acid in the prefrontal cortex (p<0.05), whereas feeding B. breve DPC6330 to non separated rats significantly increased eicosapentaenoic acid and docosapentaenoic acid in serum (p<0.05) compared with the NS un-supplemented controls. Administration of B. breve DPC6330 in combination with linoleic acid and α-linolenic acid to maternally separated rats significantly increased docosapentaenoic acid in the serum (p<0.01) and α-linolenic acid in adipose tissue (p<0.001), whereas feeding B. breve DPC6330 with fatty acid supplementation to non-separated rats significantly increased liver and serum docosapentaenoic acid (p<0.05), and α-linolenic acid in adipose tissue (p<0.001). B. breve DPC6330 influenced host fatty acid metabolism. Administration of B. breve DPC6330 to maternally separated rats significantly modified the palmitoleic acid, arachidonic acid and docosahexaenoic acid contents in tissues. The effect was not observed in non-separated animals.This work was supported by the Science Foundation of Ireland – funded Centre for Science, Engineering and Technology, the Alimentary Pharmabiotic Centre
Radio Astronomy
Contains reports on three research project.National Science Foundation (Grant GP-21348A#2)California Institute of Technology (Contract 952568)National Aeronautics and Space Administration (Grant NGR 22-009-421)U. S. Air Force - Electronic Systems Division (Contract F19628-73-C-0196
Variation and appropriateness of antipsychotic use in long-term care facilities across Newfoundland and Labrador
Objective: The use of antipsychotics to treat
seniors in long-term care facilities (LTC Fs) has raised
concern because of health consequences (i.e.,
increased risk of falls, stroke, death) in this vulnerable
population. This study measured geographic
patterns of antipsychotic utilization among seniors
living in LTC Fs in Newfoundland and Labrador (NL)
and assessed potential inappropriateness.
Method: We analyzed prescription records among
adults 66 years and older with provincial prescription
drug coverage admitted to LTC Fs in NL
between April 1, 2011, and March 31, 2014. Patterns
of use were analyzed across the 4 regional health
authorities (RHAs) in NL and LTC Fs. Logistic, Poisson
and linear regression models were used to test variations
in prevalence, rate and volume of antipsychotic
utilization. To assess potential inappropriateness
of antipsychotic use, we analyzed data from
Resident Assessment Instrument–Minimum Data
Set (RAI-MDS) 2.0 forms from NL LTC Fs between
January 1, 2016, and December 31, 2018. Pearson
chi-squared analysis was performed at the RHA and
LTC F levels to determine changes in percentage of
total prescriptions or antipsychotic prescriptions
without psychosis.
Results: Between 2011 and 2014, 2843 seniors
were admitted to LTC Fs across NL; of these, 1323
residents were prescribed 1 or more antipsychotics.
Within the 3-year period, the percentage of antipsychotic
use across facilities ranged from 35% to
78%. Using data from 27,260 RAI-MDS 2.0 assessments
between 2016 and 2018, 71% (6995/9851)
of antipsychotic prescriptions were potentially
inappropriate.
Discussion: There is substantial variation across NL
regions concerning the utilization of antipsychotics
for senior in LTC Fs. Facility size and management
styles may be reasons for this.
Conclusion: With nearly three-quarters of antipsychotic prescriptions shown to be potentially inappropriate,
systematic interventions to assess indications for antipsychotic use are warranted
Radio Astronomy
Contains reports on eight research projects.National Aeronautics and Space Administration, Langley Research Center (Contract NAS1-10693)California Institute of Technology Contract 952568Joint Services Electronics Programs (U. S. Army, U.S. Navy, and U. S. Air Force) under Contract DAAB07-71-C-0300National Science Foundation (Grant GP-20769A#1)National Science Foundation (Grant GP-21348A#1
Radio Astronomy
Contains research objectives and summary of research on seven research projects.M.I.T. Sloan Fund for Basic ResearchNational Aeronautics and Space Administration (Contract NAS5-21980)National Aeronautics and Space Administration (Contract NAS5-22485)National Aeronautics and Space Administration (Contract NAS5-23677)National Aeronautics and Space Administration (Contract NAS5-22929)U. S. Air Force - Electronic Systems Division (Contract F19628-75-C-0122)National Science Foundation (Grant AST73-05043-A02)National Science Foundation (Grant AST73-05042-A03
Where to start? The Irish Emergency Department Antimicrobial Discharge (EDAD) study:a multicentre, prospective cohort analysis
Objectives: To determine the percentage of patients across Ireland who are discharged from the Emergency Department (ED) with an antimicrobial prescription, the indication, classification of infections, and guideline compliance. To identify potential areas for antimicrobial stewardship (AMS) interventions in the ED. Patients and methods: A multicentre, prospective cohort analysis study in EDs across eight hospitals in Ireland. At each site, patients aged 1 month and older who presented to the ED and were discharged directly from the ED were included. A random selection of records of patients discharged from the ED were reviewed until a minimum of 30 records with an infection diagnosis resulting in an antibiotic prescription were obtained per hospital. The number of patient discharges with no antibiotic prescriptions were included to calculate the denominator. The indication, infection classification and guideline compliance data were collected on the 30 prescriptions in the participating hospitals. Results: A total of 2619 patient records were reviewed. Of these, 249 (9.5%) patients were discharged with antimicrobial prescriptions from the ED. Most (158; 63%) were classified as probable bacterial infection, 21 (8%) as probable viral, and 18 (7%) had no documented evidence of infection. Three indications accounted for 73% of antimicrobial prescriptions: skin/soft tissue infection; ear, nose and throat infection; and urinary tract infection. Overall guideline compliance was 64%. Conclusions: Several areas for AMS interventions to optimize antimicrobial prescribing in the ED were identified, including targeted local and national guideline reviews, delayed prescribing, improved point-of-care testing and prescriber and patient education
‘The Rest is Silence’:Psychogeography, Soundscape and Nostalgia in Pat Collins’ Silence
Guy Debord defines the term psychogeography as 'the study of the precise laws and specific effects of the geographical environment, consciously organised or not, on the emotions and behaviour of individuals' (Debord 1955: 23). Similar to the belief of psychogeographers that the geography of an environment has a psychological effect on the human mind, proponents of acoustic ecology such as R. Murray Schafer hold that humans are affected by the sound of the environment in which they find themselves. Further to this, they examine the extent to which soundscapes can be shaped by human behaviour.
Recently a body of Irish films has emerged that directly engages with the Irish soundscape and landscape on a psychogeographical level. Rather than using landscape as a physical space for the locus of action, these representations of the Irish landscape allow for an engagement with the aesthetic effects of the geographical landscape as a reflection of the psychological states of the protagonists. Bearing this in mind, this article examines how Silence (Collins 2012) arguably demonstrates the most overt and conscious incursion into this area to date. It specifically interrogates how the filmic representation of the psychogeography and soundscape of the Irish rural landscape can serve to express emotion, alienation and nostalgia, thus confronting both the Irish landscape and the weight of its associated history
Painting: Process
Catalog for the exhibition Painting: Process held at the Seton Hall University Walsh Gallery, January 14 - February 15, 2008. Curated by Jackie Bekiaris and Maria Silvestri. Includes an essay by Jackie Bekiaris and Maria Silvestri. Includes color illustrations
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