2 research outputs found
Extended-spectrum beta-lactamaseproducing bacteria in a Tertiary Care Hospital in Madrid: Epidemiology, risk factors and antimicrobial susceptibility patterns
Introduction: Extended-spectrum beta-lactamase (ESBL) producing bacteria have been increasingly reported
as causal agents of nosocomial infection worldwide. Resistance patterns vary internationally, and even locally,
from one institution to the other. We investigated the clinical isolates positive for ESBL-producing bacteria in
our institution, a tertiary care hospital in Madrid (Spain), during a 2-year period (2007 2008).
Methods: Clinical and microbiological data were retrospectively reviewed. Two hundred and nineteen patients
were included in the study.
Results: Advanced age, diabetes, use of catheters, previous hospitalization and previous antibiotic treatment
were some of the risk factors found among patients. Escherichia coli was the most frequent isolate, and
urinary tract the most common site of isolation. Internal Medicine, Intensive Care Unit (ICU) and General
Surgery presented the highest number of isolates. There were no outbreaks during the study period. Antibiotic
patterns showed high resistance rates to quinolones in all isolates. There was 100% sensitivity to carbapenems.
Conclusion: Carbapenems continue to be the treatment of choice for ESBL-producing bacteria. Infection
control measures are of great importance to avoid the spread of these nosocomial infection
Two Rare Cases of Intrahepatic Subcapsular Hematoma After Laparoscopic Cholecystectomy
The appearance of subcapsular liver hematoma after a laparoscopic cholecystectomy (LC) is an infrequent complication and seldom studied. Some cases have been connected to ketorolac given during surgery and after surgery. Other described causes are : hemangiomas or small iatrogenic lesions that could be aggravated by administration of ketorolac. Coagulation dysfunction like circulating heparin as seen in hemathological diseases is cause of bleeding after aggressive procedures. We describe two cases of subcapsular liver hematoma after LC, both of them have been given intravenous ketorolac and one of them had multiple myeloma. We discuss the causes and treatment of it