Patterns of attendance of children under 12 years at school dental service in Western Australia

Abstract: The aim of this study was to investigate the patterns of attendance at School Dental Service (SDS) and reasons for attendance (treatment or prevention) for children in the Perth Metropolitan Area, in particular investigating the first year of SDS attendance and attendance until the year the child turned 12. The first 150 SDS records located for children from the Western Australian Pregnancy Cohort (Raine) Study were used for this study. Patterns of attendance of children at SDS were described, as were associated factors (enrolment, age and nature of first visit, general nature of visits and number of visits) until the end of the year that the child turned 12. The age of the child at the first SDS visit ranged from 4 years 3 months to 14 years 11 months, with a median of 5 years 1 month. First visits were primarily for an examination (98%). Children had a median of 13 visits until 12 years of age, with 10% having less than five visits and 4% having more than 25 visits. These data provide useful information regarding attendance at the SDS in Western Australia which could provide a basis for oral health promotion programs

Streamlining Ground Station Network Compatibility Test for Small Satellites

A team of eight subject matter experts at NASA Goddard Space Flight Center (GSFC) completed a Lean Six Sigma project to identify process improvements for the compatibility test process for small satellites planning to use the NASA Near Earth Network (NEN). Ground station network compatibility testing is designed to reduce the risk to missions by resolving issues between the spacecraft's flight communication and navigation components and the ground systems prior to launch. Compatibility testing, which consists of a series of tests performed over a period of months and documented in reports, is an important step meant to prevent post-launch anomalies that could lead to expensive troubleshooting or mission failure. Compared to traditional missions, small satellite missions typically have a smaller budget and compressed schedules, which can result in small satellite projects' willingness to accept the risk associated with less comprehensive compatibility testing. Optimization and or refinement of the compatibility test process for small satellite missions could alleviate some of the pressures inherent with these factors. The goal of the Lean Six Sigma project was to develop alternative scalable methods of compatibility testing for small satellites. The Lean Six Sigma approach and the results of the project are reviewed in this paper

Age, Disease Severity and Ethnicity Influence Humoral Responses in a Multi-Ethnic COVID-19 Cohort

The COVID-19 pandemic has affected all individuals across the globe in some way. Despite large numbers of reported seroprevalence studies, there remains a limited understanding of how the magnitude and epitope utilization of the humoral immune response to SARS-CoV-2 viral anti-gens varies within populations following natural infection. Here, we designed a quantitative, multi-epitope protein microarray comprising various nucleocapsid protein structural motifs, including two structural domains and three intrinsically disordered regions. Quantitative data from the microarray provided complete differentiation between cases and pre-pandemic controls (100% sensitivity and specificity) in a case-control cohort (n = 100). We then assessed the influence of disease severity, age, and ethnicity on the strength and breadth of the humoral response in a multi-ethnic cohort (n = 138). As expected, patients with severe disease showed significantly higher antibody titers and interestingly also had significantly broader epitope coverage. A significant increase in antibody titer and epitope coverage was observed with increasing age, in both mild and severe disease, which is promising for vaccine efficacy in older individuals. Additionally, we observed significant differences in the breadth and strength of the humoral immune response in relation to ethnicity, which may reflect differences in genetic and lifestyle factors. Furthermore, our data enabled localization of the immuno-dominant epitope to the C-terminal structural domain of the viral nucleocapsid protein in two independent cohorts. Overall, we have designed, validated, and tested an advanced serological assay that enables accurate quantitation of the humoral response post natural infection and that has revealed unexpected differences in the magnitude and epitope utilization within a population

Georeferencing Accuracy Assessment of Historical Aerial Photos Using a Custom-Built Online Georeferencing Tool

As one of the earliest forms of remote sensing, aerial photography has been regarded as an important part of the mapmaking process. Aerial photos, especially historical aerial photos, provide significant amount of valuable information for many applications and fields. However, due to limited funding support, most historical aerial photos have not been digitized and georeferenced yet, which substantially limits their utility for today’s computer-based image processing and analysis. Traditionally, historical aerial photos are georeferenced with desktop GIS software applications. However, this method is expensive, time-consuming, and labor-intensive. To address these limitations, this research developed a custom-built online georeferencing tool to enable georeferencing digitized historical aerial photos in a web environment, which is able to georeference historical aerial photos in a rapid and cost-effective manner. To evaluate the georeferencing performance, a set of 50 historical aerial photos were georeferenced with not only the developed online georeferencing tool but also two commercial desktop software programs. Research results revealed the custom-built online georeferencing tool provided the highest degree of accuracy while maximizing its accessibility

Georeferencing Accuracy Assessment of Historical Aerial Photos Using a Custom-Built Online Georeferencing Tool

As one of the earliest forms of remote sensing, aerial photography has been regarded as an important part of the mapmaking process. Aerial photos, especially historical aerial photos, provide significant amount of valuable information for many applications and fields. However, due to limited funding support, most historical aerial photos have not been digitized and georeferenced yet, which substantially limits their utility for today’s computer-based image processing and analysis. Traditionally, historical aerial photos are georeferenced with desktop GIS software applications. However, this method is expensive, time-consuming, and labor-intensive. To address these limitations, this research developed a custom-built online georeferencing tool to enable georeferencing digitized historical aerial photos in a web environment, which is able to georeference historical aerial photos in a rapid and cost-effective manner. To evaluate the georeferencing performance, a set of 50 historical aerial photos were georeferenced with not only the developed online georeferencing tool but also two commercial desktop software programs. Research results revealed the custom-built online georeferencing tool provided the highest degree of accuracy while maximizing its accessibility

Bridge deck surface distress evaluation using S-UAS acquired high-spatial resolution aerial imagery

ABSTRACTBridge decks need to be routinely inspected to ensure their serviceability, capacity, and safety under current traffic conditions. Traditionally, bridge deck inspection is performed on the ground by having inspectors either visually inspect surface conditions or interpret the acoustic feedback from hammer sounding or chain dragging to determine subsurface conditions. These traditional methods have many limitations, including but not limited to, expensive, labour-intensive, time-consuming, subjective, can exhibit a high degree of variability, requiring specialized staff on a regular basis, and unsafe. Recent advancements in remote sensing, especially small-uncrewed aircraft systems (S-UAS) based airborne imaging techniques and advanced image analysis techniques, have shown promise in improving current bridge deck inspection practices by providing an above-ground inspection method. This research explored the utility of S-UAS-based airborne imaging techniques and image processing techniques to develop a complete aerial data acquisition and analysis system to accurately detect and assess bridge deck wearing surface distresses in a timely and cost-effective manner. As part of the research project, a robust tool was also developed with the aim of being able to detect, extract, and map bridge deck wearing surface distresses with an adequate degree of accuracy while maximizing the ability to assist bridge inspectors with varying expertise. Research results revealed that the developed tool is able to effectively detect and map bridge deck wearing surface distresses at a high accuracy

Nipple sparing mastectomy: can we predict the factors predisposing to necrosis?

BACKGROUND: Nipple sparing mastectomy (NSM) is an accepted surgical approach in selected breast cancer and prophylactic mastectomy, nevertheless post-mastectomy skin necrosis is one of the frequent complications. This study aimed to analyze the factors that may lead to skin necrosis after NSM. PATIENTS AND METHODS: From May 2010 to July 2010, we prospectively registered 50 consecutive NSM from 45 patients. There were 40 mastectomies for cancer, and 10 prophylactic mastectomies. The various patient's and surgical factors were registered during pre-, intra- and postoperative period. RESULTS: No total necrosis of the nipple areola complex (NAC) was observed. There were thirteen cases with partial necrosis (26.0%) of the areola or the adjacent skin. All these necrosis were partial both for the surface and the thickness. Surgical debridement was performed in 9 (18.0%) cases. The significant risk factors are smoking, young age, type of incision and NAC involvement with areola flap thickness less than 5 mm. CONCLUSION: NSM should be done with high caution in smokers. Young patients, periareolar incision and superior circumareolar incision have also a higher risk of necrosis. We recommend keeping areolar flap thickness more than 5 mm in areola region

Bone marrow fibrosis and vascular density lack prognostic significance in childhood acute lymphoblastic leukaemia

A Bharos, A-J de Jong, N Manton, N Venn, C Story, G Hodge, S Nath, R Suppiah, H Tapp, R Sutton and T Reves