120 research outputs found

    Fertility preservation in ovarian tumours

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    A considerable number of patients with a cancer diagnosis are of childbearing age and have not satisfied their desire for a family. Despite ovarian cancer (OC) usually occurring in older patients, 3%–14% are diagnosed at a fertile age with the overall 5-year survival rate being 91.2% in women ≀44 years of age when it is found at 1A–B stage. In this scenario, testing the safety and the efficacy of fertility sparing strategies in OC patients is very important overall in terms of quality of life. Unfortunately, the lack of randomised trials to validate conservative approaches does not guarantee the safety of fertility preservation strategies. However, evidence-based data from descriptive series suggest that in selected cases, the preservation of the uterus and at least one part of the ovary does not lead to a high risk of relapse. This conservative surgery helps to maintain organ function, giving patients of childbearing age the possibility to preserve their fertility. We hereby analysed the main evidence from the international literature on this topic in order to highlight the selected criteria for conservative management of OC patients, including healthy BRCA mutations carriers

    Domain ontology for digital marketplaces

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    Recently the sharing economy has emerged as a viable alternative to fulfilling a variety of consumer needs. As there is no consensus on the definition of ‘sharing economy’ we use the term ‘marketplace’ to refer more specifically to Internet/software-based sharing economy platforms connecting two different market segments. In the field of sharing economy and marketplaces we found a research gap concerning the (socio)technological aspects and the development of marketplaces. A marketplace ontology can help to have a clear account of marketplace concepts which will facilitate communication, consensus and alignment. In this paper we design this marketplace ontology in four steps. First the selection of UFO as foundation and UFO-S as core ontology. Second the search for a set of minimal conditions and properties common for marketplaces and the derivation into competency questions. Third, use the competency questions to identify fragmented sub-ontology pieces called Domain-Related Ontology Patterns (DROPs) and apply them informally by extending UFO-S concepts to design a marketplace domain ontology. This marketplace domain ontology is represented in OntoUML. The last step is the validation of the OntoUML model using expert knowledge

    The Intentional Use of Service Recovery Strategies to Influence Consumer Emotion, Cognition and Behaviour

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    Service recovery strategies have been identified as a critical factor in the success of. service organizations. This study develops a conceptual frame work to investigate how specific service recovery strategies influence the emotional, cognitive and negative behavioural responses of . consumers., as well as how emotion and cognition influence negative behavior. Understanding the impact of specific service recovery strategies will allow service providers' to more deliberately and intentionally engage in strategies that result in positive organizational outcomes. This study was conducted using a 2 x 2 between-subjects quasi-experimental design. The results suggest that service recovery has a significant impact on emotion, cognition and negative behavior. Similarly, satisfaction, negative emotion and positive emotion all influence negative behavior but distributive justice has no effect
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