6,403 research outputs found

    Nonpolar resistive switching in Cu/SiC/Au non-volatile resistive memory devices

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    Amorphous silicon carbide (a-SiC) based resistive memory (RM) Cu/a-SiC/Au devices were fabricated and their resistive switching characteristics investigated. All four possible modes of nonpolar resistive switching were achieved with ON/OFF ratio in the range 10 6-10 8. Detailed current-voltage I-V characteristics analysis suggests that the conduction mechanism in low resistance state is due to the formation of metallic filaments. Schottky emission is proven to be the dominant conduction mechanism in high resistance state which results from the Schottky contacts between the metal electrodes and SiC. ON/OFF ratios exceeding 10 7 over 10 years were also predicted from state retention characterizations. These results suggest promising application potentials for Cu/a-SiC/Au RM

    Apes communicate about absent and displaced objects: methodology matters

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    Displaced reference is the ability to refer to an item that has been moved (displaced) in space and/or time, and has been called one of the true hallmarks of referential communication. Several studies suggest that nonhuman primates have this capability, but a recent experiment concluded that in a specific situation (absent entities) human infants display displaced reference but chimpanzees do not. Here we show that chimpanzees and bonobos of diverse rearing histories are capable of displaced reference to absent and displaced objects. It is likely that some of the conflicting findings from animal cognition studies are due to relatively minor methodological differences, but are compounded by interpretation errors. Comparative studies are of great importance in elucidating the evolution of human cognition, however, greater care must be taken with methodology and interpretation for these studies to accurately reflect species differences

    Triggering social interactions:chimpanzees respond to imitation by a humanoid robot and request responses from it

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    Even the most rudimentary social cues may evoke affiliative responses in humans and promote socialcommunication and cohesion. The present work tested whether such cues of an agent may also promotecommunicative interactions in a nonhuman primate species, by examining interaction-promoting behavioursin chimpanzees. Here, chimpanzees were tested during interactions with an interactive humanoid robot, whichshowed simple bodily movements and sent out calls. The results revealed that chimpanzees exhibited twotypes of interaction-promoting behaviours during relaxed or playful contexts. First, the chimpanzees showedprolonged active interest when they were imitated by the robot. Second, the subjects requested ‘social’responses from the robot, i.e. by showing play invitations and offering toys or other objects. This study thusprovides evidence that even rudimentary cues of a robotic agent may promote social interactions inchimpanzees, like in humans. Such simple and frequent social interactions most likely provided a foundationfor sophisticated forms of affiliative communication to emerge

    Discrete model for laser driven etching and microstructuring of metallic surfaces

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    We present a unidimensional discrete solid-on-solid model evolving in time using a kinetic Monte Carlo method to simulate micro-structuring of kerfs on metallic surfaces by means of laser-induced jet-chemical etching. The precise control of the passivation layer achieved by this technique is responsible for the high resolution of the structures. However, within a certain range of experimental parameters, the microstructuring of kerfs on stainless steel surfaces with a solution of H3PO4\mathrm{H}_3\mathrm{PO}_4 shows periodic ripples, which are considered to originate from an intrinsic dynamics. The model mimics a few of the various physical and chemical processes involved and within certain parameter ranges reproduces some morphological aspects of the structures, in particular ripple regimes. We analyze the range of values of laser beam power for the appearance of ripples in both experimental and simulated kerfs. The discrete model is an extension of one that has been used previously in the context of ion sputtering and is related to a noisy version of the Kuramoto-Sivashinsky equation used extensively in the field of pattern formation.Comment: Revised version. Etching probability distribution and new simulations adde

    Dopamine elevates and lowers astroglial Ca(2+) through distinct pathways depending on local synaptic circuitry

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    Whilst astrocytes in culture invariably respond to dopamine with cytosolic Ca(2+) rises, the dopamine sensitivity of astroglia in situ and its physiological roles remain unknown. To minimize effects of experimental manipulations on astroglial physiology, here we monitored Ca(2+) in cells connected via gap junctions to astrocytes loaded whole-cell with cytosolic indicators in area CA1 of acute hippocampal slices. Aiming at high sensitivity of [Ca(2+) ] measurements, we also employed life-time imaging of the Ca(2+) indicator Oregon Green BAPTA-1. We found that dopamine triggered a dose-dependent, bidirectional Ca(2+) response in stratum radiatum astroglia, a jagged elevation accompanied and followed by below-baseline decreases. The elevation depended on D1/D2 receptors and engaged intracellular Ca(2+) storage and removal whereas the dopamine-induced [Ca(2+) ] decrease involved D2 receptors only and was sensitive to Ca(2+) channel blockade. In contrast, the stratum lacunosum moleculare astroglia generated higher-threshold dopamine-induced Ca(2+) responses which did not depend on dopamine receptors and were uncoupled from the prominent inhibitory action of dopamine on local perforant path synapses. Our findings thus suggest that a single neurotransmitter-dopamine-could either elevate or decrease astrocyte [Ca(2+) ] depending on the receptors involved, that such actions are specific to the regional neural circuitry and that they may be causally uncoupled from dopamine actions on local synapses. The results also indicate that [Ca(2+) ] elevations commonly detected in astroglia can represent the variety of distinct mechanisms acting on the microscopic scale. GLIA 2016

    The type II phase resetting curve is optimal for stochastic synchrony

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    The phase-resetting curve (PRC) describes the response of a neural oscillator to small perturbations in membrane potential. Its usefulness for predicting the dynamics of weakly coupled deterministic networks has been well characterized. However, the inputs to real neurons may often be more accurately described as barrages of synaptic noise. Effective connectivity between cells may thus arise in the form of correlations between the noisy input streams. We use constrained optimization and perturbation methods to prove that PRC shape determines susceptibility to synchrony among otherwise uncoupled noise-driven neural oscillators. PRCs can be placed into two general categories: Type I PRCs are non-negative while Type II PRCs have a large negative region. Here we show that oscillators with Type II PRCs receiving common noisy input sychronize more readily than those with Type I PRCs.Comment: 10 pages, 4 figures, submitted to Physical Review

    Abundances of Baade's Window Giants from Keck/HIRES Spectra: I. Stellar Parameters and [Fe/H] Values

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    We present the first results of a new abundance survey of the Milky Way bulge based on Keck/HIRES spectra of 27 K-giants in the Baade's Window (l=1l = 1, b=−4b = -4) field. The spectral data used in this study are of much higher resolution and signal-to-noise than previous optical studies of Galactic bulge stars. The [Fe/H] values of our stars, which range between -1.29 and +0.51+0.51, were used to recalibrate large low resolution surveys of bulge stars. Our best value for the mean [Fe/H] of the bulge is −0.10±0.04-0.10 \pm 0.04. This mean value is similar to the mean metallicity of the local disk and indicates that there cannot be a strong metallicity gradient inside the solar circle. The metallicity distribution of stars confirms that the bulge does not suffer from the so-called ``G-dwarf'' problem. This paper also details the new abundance techniques necessary to analyze very metal-rich K-giants, including a new Fe line list and regions of low blanketing for continuum identification.Comment: Accepted for publication in January 2006 Astrophysical Journal. Long tables 3--6 withheld to save space (electronic tables in journal paper). 53 pages, 10 figures, 9 table

    Strong partnerships make good partners: Insights about physician-hospital relationships from a study of physician executives

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    While physicians are likely to respond favorably in concept to hospital-based disease management and other clinical programs, they are less likely to accept their structural and functional characteristics. Because of their role at the hospital-physician interface, hospital physician executives are often tasked with implementing such programs. Given the challenges involved, a deeper understanding of the role of these executives in building the hospital-physician relationship will therefore be an important contribution. To this end, we surveyed senior physician executives at hospitals and health systems (n = 326), to assess their view of the hospital-physician relationship at their institutions, focusing especially on the role of medical staff cohesion. This article presents several of our key findings, in particular that (1) many physician executives identified their medical staff as having relatively low cohesion and (2) the perceived level of medical staff cohesion correlated strongly with the level of physician support for organizational priorities, the degree of constructive physician involvement, and success in improving the physician-hospital relationship. In light of these findings, we conclude by offering concrete recommendations for physician executives and others seeking to build medical staff cohesion in the service of clinical improvement
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