Relational Aggression: What Does it Look Like and How Does it Feel for Girls with Language-Based Learning Disabilities?

The purpose of this study is to examine the context and occurrence of relational aggression in adolescent girls with learning disabilities, as described by their personal experiences and observations. A discussion of psychosocial adjustment and relational aggression with respect to the unique characteristics of children with learning disabilities will be presented. This study will provide a qualitative description of the social problem solving skills of children with learning disabilities as reflected in their responses to common social scenarios

PERSISTENCE OF IMMUNITY TO POLIOMYELITIS AMONG A SOUTHERN POPULATION THAT RECEIVED FOUR DOSES OF OPV 5 TO OVER 15 YEARS BEFORE

The immune status against polioviruses was investigated in a population of 545 students aged 11-20 years residing in the Neapolitan area, who had completed the vaccination cycle with four doses of OPV 5 to over 15 years before. Assuming as unprotected those individuals without detectable neutralizing antibodies at the dilution 1:2, nobody resulted without protection against all types of poliovirus; 0.7% lacked antibodies only against type 1, 0.6% only against type 3 and none against type 2. A very slight decreasing trend was observed for GMT values in function of the distance from the last dose of OPV for polio 1 and 2, but not for polio 3. As expected, GMT values for polio 2 resulted higher than those for polio 1 and both were higher than those for polio 3, when calculated by age groups as well as by distance groups. The last four Italian cases of autochthonous paralytic poliomyelitis, occurred in the period 1981/83, regarded unvaccinated children aged 6 months-2 years, residing in the same geographical area to which the study population belong. In the same area a delay of immunization practices was also ascertained in the recent past. Results of this study confirm that a priority for public health services is to devote their human and economic resources to reduce the vaccination delay more than administrate a further fifth dose of OPV at the age of twelve

Demonstration of FPGA acceleration of Monte Carlo simulation

We present results from a stand-alone simulation of electron single Coulomb scattering as implemented completely on an Field Programmable Gate Array (FPGA) architecture and compared with an identical simulation on a standard CPU. FPGA architectures offer unprecedented speed-up capability for Monte Carlo simulations, however with the caveats of lengthy development cycles and resource limitation, particularly in terms of on-chip memory and DSP blocks. As a proof of principle of acceleration on an FPGA, we chose a single scattering process of electrons in water at an energy of 6 MeV. The initial code-base was implemented in C++ and optimised for CPU processing. To measure the potential performance gains of FPGAs compared to modern multi-core CPUs we computed 100M histories of a 6 MeV electron interacting in water. Without performing any hardware-specific optimisation, the results show that the FPGA implementation is over 110 times faster than an optimised parallel implementation running on 12 CPU-cores, and over 270 times faster than a sequential single-core CPU implementation. The results on both architectures were statistically equivalent. The successful implementation and acceleration results are very encouraging for the future exploitation of more sophisticated Monte Carlo simulation on FPGAs for High Energy Physics applications

A municipality-level analysis of excess mortality in Italy in the period January-April 2020

BACKGROUND: the first confirmed cases of COVID-19 in WHO European Region was reported at the end of January 2020 and, from that moment, the epidemic has been speeding up and rapidly spreading across Europe. The health, social, and economic consequences of the pandemic are difficult to evaluate, since there are many scientific uncertainties and unknowns. OBJECTIVES: the main focus of this paper is on statistical methods for profiling municipalities by excess mortality, directly or indirectly caused by COVID-19. METHODS: the use of excess mortality for all causes has been advocated as a measure of impact less vulnerable to biases. In this paper, observed mortality for all causes at municipality level in Italy in the period January-April 2020 was compared to the mortality observed in the corresponding period in the previous 5 years (2015-2019). Mortality data were made available by the Ministry of Internal Affairs Italian National Resident Population Demographic Archive and the Italian National Institute of Statistics (Istat). For each municipality, the posterior predictive distribution under a hierarchical null model was obtained. From the posterior predictive distribution, we obtained excess death counts, attributable community rates and q-values. Full Bayesian models implemented via MCMC simulations were used. RESULTS: absolute number of excess deaths highlights the burden paid by major cities to the pandemic. The Attributable Community Rate provides a detailed picture of the spread of the pandemic among the municipalities of Lombardy, Piedmont, and Emilia-Romagna Regions. Using Q-values, it is clearly recognizable evidence of an excess of mortality from late February to April 2020 in a very geographically scattered number of municipalities. A trade-off between false discoveries and false non-discoveries shows the different values of public health actions. CONCLUSIONS: despite the variety of approaches to calculate excess mortality, this study provides an original methodological approach to profile municipalities with excess deaths accounting for spatial and temporal uncertainty

Realisation of an optical pressure standard by a multi-reflection interferometric technique

A novel realization of an optical pressure standard, alternative to Fabry-Perot cavity-based techniques, is presented. It is based on the measurement of the refractive index of a gas through an unbalanced homodyne interferometer, designed to have one of its two arms formed by a multi reflection double mirror assembly to establish an unbalance length larger than 6 m in a compact setup. The paper illustrates the most important steps concerning its realization: the estimate of the pressure-induced deformation of the interferometer, the temperature control at millikelvin level and the measurement in vacuum of the unbalance of the interferometer. The evaluation of the uncertainty of the realized optical pressure standard currently demonstrated to fulfill the main goal of having the ability to measure pressure with a relative uncertainty of 10 ppm at 100 kPa

Catenary-Powered Electric Traction Network Modeling: A Data-Driven Analysis for Trolleybus System Simulation

In the context of smart cities, direct current overhead contact lines, usually adopted to power urban transportation systems such as trolleybuses, tramways, metros, and railways, can serve as a backbone to connect different modern emerging technologies. Among these, in-motion charging (IMC) trolleybuses with on-board batteries are expected to be very impactful on the DC network’s power flow and may require specific voltage and current control. These factors motivate the development of a simulation tool able to emulate these devices’ absorption and their effect on the supply infrastructure. The main innovative value of the work is to improve a simulation model of a trolleybus grid through a data-driven approach by using measurements of voltage and current output from a traction substation. The measurements are essential for understanding the behavior of vehicle weight variation throughout the day. Thanks to this information, a characterization of the current draw by conventional trolleybuses and IMC trolleybuses is then provided for each trolleybus route in a specific power section of the Bologna trolleybus system. By integrating the variation in vehicle weight within the model, a simulation of a possible daily operation of a trolleybus feeding section has been performed, obtaining a 7% error between the daily energy calculated from the simulation and that obtained through measurements. This analysis demonstrates the feasibility of the adopted simulation tool, which can also be used to evaluate additional hypothetical trolleybus operation scenarios. One of these possible scenarios considers IMC vehicles, and it is also evaluated in this paper

Novel Multi‐Vehicle Motion‐Based Model of Trolleybus Grids towards Smarter Urban Mobility

Trolleybus systems are resurfacing as a steppingstone to carbon-neutral urban transport. With an eye on smart city evolution, the study and simulation of a proper monitoring system for trolleybus infrastructures will be essential. This paper merges the authors’ engineering knowledge and sources available in the literature on designing and modeling catenary-based electric traction networks and performs a critical review of them to lay the foundations for proposing possible optimal alternatives. A novel multi-vehicle motion-based model of the DC catenary system is then devised and simulated in Matlab-Simulink, which could prove useful in predicting possible technical obstacles arising from the next-future introduction of smart electric traction grids, inevitably featuring greater morphological intricacy. The modularity property characterizing the created model allows an accurate, detailed, and flexible simulation of sophisticated catenary systems. By means of graphical and numerical results illustrating the behavior of the main electrical line parameters, the presented approach demonstrates today’s obsolescence of conventional design methods used so far. The trolleybus network of the city of Bologna was chosen as a case study

Inflammatory polyradiculoneuropathies: Clinical and immunological aspects, current therapies, and future perspectives

Inflammatory polyradiculoneuropathies are heterogeneous disorders characterized by immune-mediated leukocyte infiltration of peripheral nerves and nerve roots leading to demyelination or axonal degeneration or both. Inflammatory polyradiculoneuropathies can be divided into acute and chronic: Guillain–Barré syndrome and chronic inflammatory demyelinating polyneuropathy and their variants. Despite major advances in immunology and molecular biology have been made in the last years, the pathogenesis of these disorders is not completely understood. This review summarizes the current literature of the clinical features and pathogenic mechanisms of inflammatory polyradiculoneuropathies and focuses on current therapies and new potential treatment for the future