Co-axial wet-spinning in 3D Bioprinting: state of the art and future perspective of microfluidic integration

Nowadays, 3D bioprinting technologies are rapidly emerging in the field of tissue engineering and regenerative medicine as effective tools enabling the fabrication of advanced tissue constructs that can recapitulate in vitro organ/tissue functions. Selecting the best strategy for bioink deposition is often challenging and time consuming process, as bioink properties-in the first instance, rheological and gelation-strongly influence the suitable paradigms for its deposition. In this short review, we critically discuss one of the available approaches used for bioprinting-namely co-axial wet-spinning extrusion. Such a deposition system, in fact, demonstrated to be promising in terms of printing resolution, shape fidelity and versatility when compared to other methods. An overview of the performances of co-axial technology in the deposition of cellularized hydrogel fibres is discussed, highlighting its main features. Furthermore, we show how this approach allows (i) to decouple the printing accuracy from bioink rheological behaviour-thus notably simplifying the development of new bioinks- A nd (ii) to build heterogeneous multi-materials and/or multicellular constructs that can better mimic the native tissues when combined with microfluidic systems. Finally, the ongoing challenges and the future perspectives for the ultimate fabrication of functional constructs for advanced research studies are highlighted. © 2018 IOP Publishing Ltd

Contributions to the legal question of peasant labor in an Argentina based around agribusiness

La consolidación del agronegocio ha aumentado la conflictualidad en el agro argentino en torno a la propiedad de la tierra como consecuencia de situaciones problemáticas de tenencia de la tierra y el uso de los bienes naturales (agua, bosques), una expansión de los problemas ambientales y casos de contaminación rural, la emergencia de la violencia en el campo (desalojos y/o cercamiento de poblaciones indígenas y campesinas, entre otros hechos violentos). En este trabajo, nuestra intención realizar un aporte a la cuestión jurídica campesina haciendo énfasis, por un lado, en el rol asumido por el poder judicial en la disputa por la propiedad de la tierra entre campesinos y empresarios; por el otro, a través de la indagación en torno las acciones llevadas a cabo por los poderes políticos (ejecutivo y legislativo) ?nacional y/o provincial con el objetivo de llevar a cabo la regularización de las posesiones campesinas.Fil: Barbetta, Pablo Nicolas. Universidad de Buenos Aires. Facultad de Ciencias Sociales. Instituto de Investigaciones "Gino Germani"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Highly permeable macroporous polymers synthesized from pickering medium and high internal phase emulsion templates

Open porous poly-Plckerlng-M/HIPEs with permeabilities of up to 2.6 D were prepared by polymerisation of PickeringM/HIPEs to which small amounts of surfactant were added. The permeability of these poly-Pickering-M/HIPEs is more than 5 times that of conventional polyHI PEs. This approach allows the synthesis of a novel class of permeable particle reinforced macroporous polymers with significant potential for practical exploitation. (Figure Presented) © 2010 WILEY-VCH VerlagGmbH S.Co. KCaA, Weinheim

On the surface tension of fluctuating quasi-spherical vesicles

We calculate the stress tensor for a quasi-spherical vesicle and we thermally average it in order to obtain the actual, mechanical, surface tension $\tau$ of the vesicle. Both closed and poked vesicles are considered. We recover our results for $\tau$ by differentiating the free-energy with respect to the proper projected area. We show that $\tau$ may become negative well before the transition to oblate shapes and that it may reach quite large negative values in the case of small vesicles. This implies that spherical vesicles may have an inner pressure lower than the outer one.Comment: To appear in Eur. Phys. J. E, revised versio

The Effects of Repeated Readings on Reading Abilities of English Language Learners with Specific Learning Disabilities

This study evaluates the effects of repeated readings on the reading fluency and comprehension of 4 third through fifth grade English Language Learners (ELLs) with Specific Learning Disabilities (SLD). The results indicate gains in fluency, a decrease in errors, and an increase in correct answers to literal comprehension questions

Community recreation- campesinado in -jurídica partner interface: the case of the ex limitas

La consolidación del modelo del agronegocio en Argentina trajo consigo mayores niveles de concentración de la tierra y tendió, de diversos modos, a profundizar procesos de exclusión y expulsión de familias del campo. Al mismo tiempo, supuso un aumento de la conflictualidad en el agro argentino en torno a la propiedad de la tierra y el uso de los bienes naturales. El alcance de este proceso se puede observar en la creciente conflictualidad territorial en áreas rurales puesto que allí se activa la presencia de una intencionalidad campesina que reivindica un modo de vida y su derecho a la tierra. La provincia del Chaco no está excluida de dichos procesos. En este contexto de vitalidad social y política del campesinado chaqueño nos interesa analizar y comprender el proceso de “invención” de una figura de tenencia comunitaria del territorio en el Paraje Limitas, departamento de Bermejo, en el marco del proceso organizativo de la Unión de Pequeños Productores del Chaco (UNPEPROCH). Más precisamente, nos proponemos indagar los procesos que confluyeron en esta figura que realiza el derecho a la tierra en una interfase socio jurídica, en donde intervienen las poblaciones pre existentes, trabajadores sin tierra, el Estado y actores del agronegocio.The consolidation model of agribusiness in Argentina resulted in higher levels of land concentration and tended in various ways to deepen processes of exclusion and expulsion of rural families. At the same time, meant an increase in the Argentine agro conflictivity around land ownership and use of natural resources. The scope of this process can be seen in the growing territorial conflictivity in rural areas because there the presence of intentionality that campesinas a peasant way of life and their right to land on. The province of Chaco is not excluded from these processes. In this context of social and political vitality of the Chaco peasantry we want to analyze and understand the process of "invention" of a figure of communal tenure of land in the Place Limitas, Bermejo department, under the organizational process of the Union of small producers Chaco (UNPEPROCH). More precisely, we propose to investigate the processes which will converge in this figure performing the right to land in a legal partner interface, where the pre-existing, landless workers, the state and agribusiness actors involved populations.Fil: Domínguez, Diego Ignacio. Universidad de Buenos Aires. Facultad de Ciencias Sociales. Instituto de Investigaciones ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Barbetta, Pablo Nicolas. Universidad de Buenos Aires. Facultad de Ciencias Sociales. Instituto de Investigaciones ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

The Impact of Traineeships on the Employment of the Mentally Ill: The Role of Partial Compliance

Lavoro&Psiche is a RCT aimed at increasing employment among severely mentally ill patients, by offering them a structured job-search experience. The key feature of the treatment was the presence of a "job coach" entirely dedicated to support the job search of a small number (12-13) of mentally ill patients. What most often the job coach did was finding the patient a traineeship. If one were to consider only the effect of making the support of the coach available the so-called Intention-To-Treat effect it would be a disappointing statistically non significant 5 percentage point difference in the employment of treatment and control members, in the full post-treatment year. However, the impact of making something available is rarely the primary interest of policy-makers, who would rather know the effect of receiving it. The main difficulty in obtaining unbiased estimates of the latter is that 'who receives what' is no longer solely determined by randomization, but also by post-randomization events and decisions. During the implementation period of Lavoro&Psiche of 2011-12, an unprecedented wave of traineeship opportunities hit those enrolled in the demonstration, both in the experimental and in the control group. The main finding is that, for the subset of the experimental group that was induced by the offer to be involved in a traineeship the chances of having a job in the post-treatment year more than double from the 17% of those who did not do any traineeship to the 34% of those who did, well above the Intention-To-Treat impact estimates