Planning the cultural quarter in Birmingham's Eastside

Cultural planning and the development of cultural quarters has become a new orthodoxy in the revitalization of inner city industrial districts, yet this orthodoxy is now widely questioned as to whether it delivers on its promises. In Birmingham UK, the aim to create a new cultural quarter in the industrial inner city area of Eastside represents a unique opportunity for the city to examine and learn from past lessons of the "cultural turn" in urban policy. The article examines these lessons and whether the Eastside scheme is set to repeat the mistakes of the past

Fronts and frontogenesis as revealed by high time resolution data

Upper air sounding are used to examine a cold front of average intensity. Vertical cross sections of potential temperature and wind, and horizontal analyses were compared and adjusted for consistency. These analyses were then used to study the evolution of the front, found to consist of a complex system of fronts occurring at all levels of the troposphere. Low level fronts were strongest at the surface and rapidly weakened with height. Fronts in the midddle troposphere were much more intense. The warm air ahead of the fronts was nearly barotropic, while the cold air behind was baroclinic through deep layers. A deep mixed layer was observed to grow in this cold air

Impact and Cost-Effectiveness of Point-Of-Care CD4 Testing on the HIV Epidemic in South Africa.

Rapid diagnostic tools have been shown to improve linkage of patients to care. In the context of infectious diseases, assessing the impact and cost-effectiveness of such tools at the population level, accounting for both direct and indirect effects, is key to informing adoption of these tools. Point-of-care (POC) CD4 testing has been shown to be highly effective in increasing the proportion of HIV positive patients who initiate ART. We assess the impact and cost-effectiveness of introducing POC CD4 testing at the population level in South Africa in a range of care contexts, using a dynamic compartmental model of HIV transmission, calibrated to the South African HIV epidemic. We performed a meta-analysis to quantify the differences between POC and laboratory CD4 testing on the proportion linking to care following CD4 testing. Cumulative infections averted and incremental cost-effectiveness ratios (ICERs) were estimated over one and three years. We estimated that POC CD4 testing introduced in the current South African care context can prevent 1.7% (95% CI: 0.4% - 4.3%) of new HIV infections over 1 year. In that context, POC CD4 testing was cost-effective 99.8% of the time after 1 year with a median estimated ICER of US$4,468/DALY averted. In healthcare contexts with expanded HIV testing and improved retention in care, POC CD4 testing only became cost-effective after 3 years. The results were similar when, in addition, ART was offered irrespective of CD4 count, and CD4 testing was used for clinical assessment. Our findings suggest that even if ART is expanded to all HIV positive individuals and HIV testing efforts are increased in the near future, POC CD4 testing is a cost-effective tool, even within a short time horizon. Our study also illustrates the importance of evaluating the potential impact of such diagnostic technologies at the population level, so that indirect benefits and costs can be incorporated into estimations of cost-effectiveness

Stepping outside normative neoliberal discourse: youth and disability meet – the case of Jody McIntyre

In May 2010, amidst the ‘global financial crisis’ a Conservative/Liberal Democrat coalition government succeeded a 12-year reign of New Labour in the United Kingdom, and ushered in massive welfare cuts. Although New Labour tabled major welfare and disability benefit reform, they arguably did not activate the harshest of these. This paper focuses on the backlash of youth and disability in the form of demonstrations; two groups that are being hit hard by the political shift to work-first welfare in an era of employment scarcity. The case of young disabled activist Jody McIntyre is used to explore parallels and divergences in neoliberal and ‘populist’ discourses of ‘risky’, troubling’ youth and disability

THE INFLUENCE OF SALMONELLA IN PIGS PRE-HARVEST ON SALMONELLA HUMAN HEALTH COSTS AND RISK FROM PORK

Salmonellosis in people is a costly disease, much of it occurring because of food associated exposure. We develop a farm-to-fork model which estimates the pork associated Salmonella risk and human health costs. This analysis focuses on the components of the pork production chain up to the point of producing a chilled pork carcass. Sensitivity and scenario analysis show that changes that occur in Salmonella status during processing are substantially more important for human health risk and have a higher benefit/cost ratio for application of strategies that control Salmonella compared with on-farm strategies.Food Consumption/Nutrition/Food Safety,

Finite size scaling of the correlation length above the upper critical dimension

We show numerically that correlation length at the critical point in the five-dimensional Ising model varies with system size L as L^{5/4}, rather than proportional to L as in standard finite size scaling (FSS) theory. Our results confirm a hypothesis that FSS expressions in dimension d greater than the upper critical dimension of 4 should have L replaced by L^{d/4} for cubic samples with periodic boundary conditions. We also investigate numerically the logarithmic corrections to FSS in d = 4.Comment: 5 pages, 6 postscript figure

The Canon and the Constitution Outside the Courts

Symposium: The Canon(s) of Constitutional La

X-Ray Emission from the Warm Hot Intergalactic Medium

The number of detected baryons in the Universe at z<0.5 is much smaller than predicted by standard big bang nucleosynthesis and by the detailed observation of the Lyman alpha forest at red-shift z=2. Hydrodynamical simulations indicate that a large fraction of the baryons today is expected to be in a ``warm-hot'' (10^5-10^7K) filamentary gas, distributed in the intergalactic medium. This gas, if it exists, should be observable only in the soft X-ray and UV bands. Using the predictions of a particular hydrodynamic model, we simulated the expected X-ray flux as a function of energy in the 0.1-2 keV band due to the Warm-Hot Intergalactic Medium (WHIM), and compared it with the flux from local and high red-shift diffuse components. Our results show that as much as 20% of the total diffuse X-ray background (DXB) in the energy range 0.37-0.925keV could be due to X-ray flux from the WHIM, 70% of which comes from filaments at redshift z between 0.1 and 0.6. Simulations done using a FOV of 3', comparable with that of Suzaku and Constellation-X, show that in more than 20% of the observations we expect the WHIM flux to contribute to more than 20% of the DXB. These simulations also show that in about 10% of all the observations a single bright filament in the FOV accounts, alone, for more than 20% of the DXB flux. Red-shifted oxygen lines should be clearly visible in these observations.Comment: 19 pages, 6 figure

Optimal Axes of Siberian Snakes for Polarized Proton Acceleration

Accelerating polarized proton beams and storing them for many turns can lead to a loss of polarization when accelerating through energies where a spin rotation frequency is in resonance with orbit oscillation frequencies. First-order resonance effects can be avoided by installing Siberian Snakes in the ring, devices which rotate the spin by 180 degrees around the snake axis while not changing the beam's orbit significantly. For large rings, several Siberian Snakes are required. Here a criterion will be derived that allows to find an optimal choice of the snake axes. Rings with super-period four are analyzed in detail, and the HERA proton ring is used as an example for approximate four-fold symmetry. The proposed arrangement of Siberian Snakes matches their effects so that all spin-orbit coupling integrals vanish at all energies and therefore there is no first-order spin-orbit coupling at all for this choice, which I call snakes matching. It will be shown that in general at least eight Siberian Snakes are needed and that there are exactly four possibilities to arrange their axes. When the betatron phase advance between snakes is chosen suitably, four Siberian Snakes can be sufficient. To show that favorable choice of snakes have been found, polarized protons are tracked for part of HERA-p's acceleration cycle which shows that polarization is preserved best for the here proposed arrangement of Siberian Snakes.Comment: 14 pages, 16 figure

Constitutional Theory and the Future of the Unitary Executive

This Essay outlines part of a larger project on executive power. Like that larger work, these remarks are as much about the future of constitutional theory¿the form it should take and the questions it should address¿as they are about the future of the unitary executive