6,120 research outputs found

    Florida Teletraining Project: Reconfiguration Of Military Courses For Video Teletraining Delivery

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    Describes the processes and procedures used by the Florida Teletraining Project (FTP) to reconfigure five military courses for delivery over the U.S. Army\u27s Teletraining Network, TNET

    Florida Teletraining Project: Final Report

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    A Comparison of the Parent-Child Interactions Between Russian Immigrant and Non-immigrant Families in a Rural Setting in Missouri

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    The purpose of this study was to compare the parent/child interactions between Russian immigrant and non-immigrant families in a rural Missouri school setting. A questionnaire was administered to 30 American families and 30 Russian immigrant families. Data concerning developmental level upon kindergarten entry were gathered from kindergarten screening protocols. Findings revealed that there were significance differences between the two sets of parents for the twelve literacy activities. Also significant differences were found regarding developmental levels between children who received Head Start as compared to those who attended preschool. Implications for early childhood literacy programs and the development of preschool language immersion programs within rural settings are significant. Also implications regarding understanding other ethnicities and cultures by rural educators are important

    Modeling cancer metabolism on a genome scale

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    Cancer cells have fundamentally altered cellular metabolism that is associated with their tumorigenicity and malignancy. In addition to the widely studied Warburg effect, several new key metabolic alterations in cancer have been established over the last decade, leading to the recognition that altered tumor metabolism is one of the hallmarks of cancer. Deciphering the full scope and functional implications of the dysregulated metabolism in cancer requires both the advancement of a variety of omics measurements and the advancement of computational approaches for the analysis and contextualization of the accumulated data. Encouragingly, while the metabolic network is highly interconnected and complex, it is at the same time probably the best characterized cellular network. Following, this review discusses the challenges that genome‐scale modeling of cancer metabolism has been facing. We survey several recent studies demonstrating the first strides that have been done, testifying to the value of this approach in portraying a network‐level view of the cancer metabolism and in identifying novel drug targets and biomarkers. Finally, we outline a few new steps that may further advance this field

    Recovery of a medieval Brucella melitensis genome using shotgun metagenomics

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    Shotgun metagenomics provides a powerful assumption-free approach to the recovery of pathogen genomes from contemporary and historical material. We sequenced the metagenome of a calcified nodule from the skeleton of a 14th-century middle-aged male excavated from the medieval Sardinian settlement of Geridu. We obtained 6.5-fold coverage of a Brucella melitensis genome. Sequence reads from this genome showed signatures typical of ancient or aged DNA. Despite the relatively low coverage, we were able to use information from single-nucleotide polymorphisms to place the medieval pathogen genome within a clade of B. melitensis strains that included the well-studied Ether strain and two other recent Italian isolates. We confirmed this placement using information from deletions and IS711 insertions. We conclude that metagenomics stands ready to document past and present infections, shedding light on the emergence, evolution, and spread of microbial pathogens

    Accounting Program Assessment: Exit Interviews of Graduating Seniors

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    Exit interviews of university graduating seniors have been used to a very limited extent when evaluating academic programs.  It is our belief that developing and implementing an exit interview plan stimulates faculty dialog and improves ongoing feedback for department program assessment.  From 2001 to 2007, the Accounting Department at Towson University has conducted exit interviews with all graduating seniors as part of the annual internal department assessment activities.  The exit interviews have served to assist the Department of Accounting in evaluating its performance as judged by the students served.  The positive comments assist to reinforce the quality activities of the department, while the negative comments permit the department to become aware of areas of perceived weakness that are in need of improvement.   By receiving annual feedback from a valuable, relevant source, the department is able to continuously monitor, adjust, and improve its performance
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