14,763 research outputs found
Fever of Unknown Origin: An Unusual Case
Recurrent episodic fever of unknown origin (FUO) arising from tumour of the gastrointestinal tract is rare. We report an otherwise healthy 62-year-old man with recurrent circumscribed bouts of fever and raised CRP for 3 years who has remained well and fever-free 2 years after the removal of a well-differentiated adenocarcinoma of the colon. Occult colonic neoplasm should be considered and sought when routine investigations for FUO are negative
Insular Carcinoma of Thyroid Presenting as a Giant Skull Lesion: A Dilemma in Treatment.
Thyroid surgeons are becoming increasingly more aware of a histologically distinct subset of thyroid carcinoma whose classification falls between well-differentiated and anaplastic carcinomas with respect to both cell differentiation and clinical behavior. This subtype of tumors has been categorized as poorly differentiated or insular carcinoma, based on its characteristic cell groupings. Although the differentiation of insular carcinoma from other thyroid carcinomas has important prognostic and therapeutic significance, relatively little about insular carcinoma has been published in the otolaryngology literature. In this article, we discuss a case of insular carcinoma of thyroid presenting with concurrent distant metastasis to skull, lung, ribs, and inguinal region with review of the literature. We conclude that insular thyroid carcinoma warrants aggressive management with total thyroidectomy and excision of accessible giant lesion followed by radioactive iodine ablation of any remaining thyroid tissue
On the number of matroids
We consider the problem of determining , the number of matroids on
elements. The best known lower bound on is due to Knuth (1974) who showed
that is at least . On the other hand, Piff
(1973) showed that , and it has
been conjectured since that the right answer is perhaps closer to Knuth's
bound.
We show that this is indeed the case, and prove an upper bound on that is within an additive term of Knuth's lower bound. Our proof
is based on using some structural properties of non-bases in a matroid together
with some properties of independent sets in the Johnson graph to give a
compressed representation of matroids.Comment: Final version, 17 page
An entropy argument for counting matroids
We show how a direct application of Shearers' Lemma gives an almost optimum
bound on the number of matroids on elements.Comment: Short note, 4 page
Pion-less effective field theory for atomic nuclei and lattice nuclei
We compute the medium-mass nuclei O and Ca using pionless
effective field theory (EFT) at next-to-leading order (NLO). The low-energy
coefficients of the EFT Hamiltonian are adjusted to experimantal data for
nuclei with mass numbers and , or alternatively to results from
lattice quantum chromodynamics (QCD) at an unphysical pion mass of 806 MeV. The
EFT is implemented through a discrete variable representation in the harmonic
oscillator basis. This approach ensures rapid convergence with respect to the
size of the model space and facilitates the computation of medium-mass nuclei.
At NLO the nuclei O and Ca are bound with respect to decay into
alpha particles. Binding energies per nucleon are 9-10 MeV and 30-40 MeV at
pion masses of 140 MeV and 806 MeV, respectively.Comment: 26 page
A New Simulation Metric to Determine Safe Environments and Controllers for Systems with Unknown Dynamics
We consider the problem of extracting safe environments and controllers for
reach-avoid objectives for systems with known state and control spaces, but
unknown dynamics. In a given environment, a common approach is to synthesize a
controller from an abstraction or a model of the system (potentially learned
from data). However, in many situations, the relationship between the dynamics
of the model and the \textit{actual system} is not known; and hence it is
difficult to provide safety guarantees for the system. In such cases, the
Standard Simulation Metric (SSM), defined as the worst-case norm distance
between the model and the system output trajectories, can be used to modify a
reach-avoid specification for the system into a more stringent specification
for the abstraction. Nevertheless, the obtained distance, and hence the
modified specification, can be quite conservative. This limits the set of
environments for which a safe controller can be obtained. We propose SPEC, a
specification-centric simulation metric, which overcomes these limitations by
computing the distance using only the trajectories that violate the
specification for the system. We show that modifying a reach-avoid
specification with SPEC allows us to synthesize a safe controller for a larger
set of environments compared to SSM. We also propose a probabilistic method to
compute SPEC for a general class of systems. Case studies using simulators for
quadrotors and autonomous cars illustrate the advantages of the proposed metric
for determining safe environment sets and controllers.Comment: 22nd ACM International Conference on Hybrid Systems: Computation and
Control (2019
Electric power demand forecasting: A case study of Lucknow city
The study of forecasting identifies the urgent need for special attention in evolving effective energy policies to alleviate an energy famine in the near future. Since power demand is increasing day by day in entire world and it is also one of the fundamental infrastructure input for the development, its prospects and availability sets significant constraints on the socio-economic growth of every person as well as every country. A care full long-term power plan is imperative for the development of power sector. This need assumes more importance in the state of Uttar Pradesh where the demand for electrical energy is growing at a rapid pace. This study analyses the requirement of electricity with respect to the future population for the major forms of energy in the Lucknow city in Uttar Pradesh state of India. A model consisting of significant key energy indicators have been used for the estimation. Model wherever required refined in the second stage to remove the effect of auto-correlation. The accuracy of the model has been checked using standard statistical techniques and validated against the past data by testing for 'expost' forecast accuracy
Silicon amendment induces synergistic plant defense mechanism against pink stem borer (Sesamia inferens Walker.) in finger millet (Eleusine coracana Gaertn.).
Silicon (Si) uptake and accumulation in plants can mitigate various biotic stresses through enhanced plant resistance against wide range of herbivores. But the role of silicon in defense molecular mechanism still remains to be elucidated in finger millet. In the present study, we identified three silicon transporter genes viz. EcLsi1, EcLsi2, and EcLsi6 involved in silicon uptake mechanism. In addition, the study also identified and characterized ten different Si transporters genes from finger millet through transcriptome assembly. The phylogenetic study revealed that EcLsi1 and EcLsi6 are homologs while EcLsi2 and EcLsi3 form another pair of homologs. EcLsi1 and EcLsi6 belong to family of NIP2s (Nod26-like major intrinsic protein), bona fide silicon transporters, whereas EcLsi2 and EcLsi3, an efflux Si transporter, belong to an uncharacterized anion transporter family having a significant identity with putative arsB transporter proteins. Further, the phylogenetic and topology analysis suggest that EcLsi1 and EcLsi2 co-evolved during evolution while, EcLsi2 and EcLsi3 are evolved from either EcLsi1 and/or EcLsi6 by fusion or duplication event. Moreover, these silicon transporters are predicted to be localized in plasma membrane, but their structural differences indicate that they might have differences in their silicon uptake ability. Silicon amendment induces the synergistic defense mechanism by significantly increasing the transcript level of silicon transporter genes (EcLsi1, EcLsi2 and EcLsi6) as well as defense hormone regulating genes (EcSAM, EcPAL and EcLOX) at 72 hpi (hours of post infestation) in both stem and roots compared to non-silicon treated plants against pink stem borer in finger millet plants. This study will help to understand the molecular defense mechanism for developing strategies for insect pest management
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