54 research outputs found

    Disparate View Matching

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    Matching of disparate views has gained significance in computer vision due to its role in many novel application areas. Being able to match images of the same scene captured during day and night, between a historic and contemporary picture of a scene, and between aerial and ground-level views of a building facade all enable novel applications ranging from loop-closure detection for structure-from-motion and re-photography to geo-localization of a street-level image using reference imagery captured from the air. The goal of this work is to develop novel features and methods that address matching problems where direct appearance-based correspondences are either difficult to obtain or infeasible because of the lack of appearance similarity altogether. To address these problems, we propose methods that span the appearance-geometry spectrum in terms of both the use of these cues as well as the ability of each method to handle variations in appearance and geometry. First, we consider the problem of geo-localization of a query street-level image using a reference database of building facades captured from a bird\u27s eye view. To address this wide-baseline facade matching problem, a novel scale-selective self-similarity feature that avoids direct comparison of appearance between disparate facade images is presented. Next, to address image matching problems with more extreme appearance variation, a novel representation for matchable images expressed in terms of the eigen-functions of the joint graph of the two images is presented. This representation is used to derive features that are persistent across wide variations in appearance. Next, the problem setting of matching between a street-level image and a digital elevation map (DEM) is considered. Given the limited appearance information available in this scenario, the matching approach has to rely more significantly on geometric cues. Therefore, a purely geometric method to establish correspondences between building corners in the DEM and the visible corners in the query image is presented. Finally, to generalize this problem setting we address the problem of establishing correspondences between 3D and 2D point clouds using geometric means alone. A novel framework for incorporating purely geometric constraints into a higher-order graph matching framework is presented with specific formulations for the three-point calibrated absolute camera pose problem (P3P), two-point upright camera pose problem (Up2p) and the three-plus-one relative camera pose problem

    Using CRISPR/Cas9 based genetic screen to understand the role of Flk1 in the specification of endothelial and blood lineages

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    Tesis doctoral inédita leída en la Universidad Autónoma de Madrid, Facultad de Medicina, Departamento de Bioquímica. Fecha de lectura: 25-05-2020Esta tesis tiene embargado el acceso al texto completo hasta el 25-11-202

    Evaluation of heavy metal resistance profile of Candida parapsilosis

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    64-68Heavy metals have caused a lot of imbalance in the environment due to its widespread ill effects. There have been tremendous efforts to reduce the levels of these metals from the environment, but demerits of existing methods exceed over the merits in most of the cases and hence there is a need for more effective mechanisms. In the present study, resistance profile of Candida parapsilosis was studied against various heavy metals. A time based tolerance study was performed using up to 12 mM concentrations of heavy metal salts such as zinc sulfate (Zn), cupric sulfate (Cu), lead acetate (Pb), mercury chloride (Hg), nickel sulfate (Ni), and potassium chromate (Cr). It was observed that tolerance against heavy metal depends upon its concentration as well as time of exposure. The obtained pattern of resistance for each individual heavy metal was Ni > Zn > Cu > Cr > Pb > Hg. Maximum growth of 57.6% was obtained for Ni salt and least for Hg with 26.9% cell viability at 12 mM concentration. Cell viability decreased as time of exposure was increased. After 72 h only 16.4% cell growth was obtained for Hg as compared to Ni showing cell viability of 37.5% up to 12 mM concentration. Significant resistance to other salts such as Zn, Cu, Cr and Pd have also been shown by C. parapsilosis

    Regular mosaic pattern development: A study of the interplay between lateral inhibition, apoptosis and differential adhesion

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    <p>Abstract</p> <p>Background</p> <p>A significant body of literature is devoted to modeling developmental mechanisms that create patterns within groups of initially equivalent embryonic cells. Although it is clear that these mechanisms do not function in isolation, the timing of and interactions between these mechanisms during embryogenesis is not well known. In this work, a computational approach was taken to understand how lateral inhibition, differential adhesion and programmed cell death can interact to create a mosaic pattern of biologically realistic primary and secondary cells, such as that formed by sensory (primary) and supporting (secondary) cells of the developing chick inner ear epithelium.</p> <p>Results</p> <p>Four different models that interlaced cellular patterning mechanisms in a variety of ways were examined and their output compared to the mosaic of sensory and supporting cells that develops in the chick inner ear sensory epithelium. The results show that: 1) no single patterning mechanism can create a 2-dimensional mosaic pattern of the regularity seen in the chick inner ear; 2) cell death was essential to generate the most regular mosaics, even through extensive cell death has not been reported for the developing basilar papilla; 3) a model that includes an iterative loop of lateral inhibition, programmed cell death and cell rearrangements driven by differential adhesion created mosaics of primary and secondary cells that are more regular than the basilar papilla; 4) this same model was much more robust to changes in homo- and heterotypic cell-cell adhesive differences than models that considered either fewer patterning mechanisms or single rather than iterative use of each mechanism.</p> <p>Conclusion</p> <p>Patterning the embryo requires collaboration between multiple mechanisms that operate iteratively. Interlacing these mechanisms into feedback loops not only refines the output patterns, but also increases the robustness of patterning to varying initial cell states.</p

    Student-Led Undergraduate Journals: A Catalyst for Comprehensive Research Experience and Professional Growth

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    This opinion piece underscores the critical role of undergraduate academic journals in fostering a comprehensive research experience for students, with a spotlight on Qapsule, an open-access journal at Queen’s University led by undergraduates. These journals offer a unique platform for students to engage in the full spectrum of scientific inquiry, from conducting research to writing, peer review, and publication. The paper emphasizes the importance of undergraduate students’ involvement in all aspects of research, discussing its crucial role in intellectual growth and professional development. However, these journals often remain under-utilized due to a lack of awareness. The paper discusses the importance of universities actively promoting these journals and providing the necessary resources for students to establish such platforms, thereby nurturing a culture of academic collaboration, creativity, and excellence. It also addresses quality concerns about undergraduate journals, asserting that with appropriate mentorship and guidance, undergraduate students are capable of contributing to the academic community

    Design and Analysis of High-Performance and Low-Power Quaternary Latch,Quaternary D Flip-Flop and XY Flip-Flop

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    Multiple-valued logic (MVL) circuits propose a number of possible improvements to current VLSI circuit designs. Forexample, serious difficulties with limitations on the number of connections between an integrated circuit and the outside world(pinout concern) and also the number of links within the circuit encountered in some VLSI circuit synthesis could be greatlyreduced if signals in the circuit could assume four or more states instead of only two. This research work shows a quaternarylogic-based latch, a level-sensitive flop, and an edge-sensitive flop. In most of the cases it is seen that a sequential digital circuitproduces two outputs which are complementary to each other. But in most of the designs, there is no need of having both theoutputs of the flip-flops, so one of the quaternary outputs can be removed from the circuit, resulting in a decrease in area andstatic power. In quaternary circuits, several power sources or a single power supply source are employed. Those that haveseveral sources of supply use less energy. In multiple-valued logic we need the design to have multiple logic levels, like inquaternary logic, GND is used for logic ‘0’, 1/3Vdd is used for logic ‘1’, 2/3Vdd is for logic ‘2’, and Vdd is for logic ‘3’. Themulti-Vdd design method is incompatible with the purpose of reducing the inter-chip and intra-chip connections. In order toresolve this, a capacitive divider network is used while designing. The QFF is demonstrated with the necessary simulationresults using LTSpice tool and the simulations are performed using 32nm technology file. Finally, a quaternary shift register isbuilt to demonstrate the applicability and appropriate operation of the proposed QFF in larger sequential circuits
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