1,169 research outputs found

    FAR Part 139 Certificated Airports Shifting Towards Environmentally-Friendly Practices

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    While the aviation industry has grown dramatically in the past 100 years, it has done so with minimal environmental awareness. Leaders in the industry must become more conscious of environmentally-friendly practices available for airport use. This research provides a discussion of technology and sustainable practices available for use at U.S. airports. This research also provides funding information available to airports for sustainable projects. The methodology used in this research study was a review of literature that examined environmental reports, federal regulations, periodicals, political statements, and professional articles related to the topic. Environmental sustainability and climate change as it relates to airport sustainability is also defined. The Federal Aviation Administration (FAA) issues operating certificates and provides regulatory oversight for all Federal Aviation Regulation (FAR) Part 139 airports. FAR Part 139 certificated airports are the largest and busiest air carrier service airports in the United States. Several industry leading airports recognize the need to pursue environmental conservation initiatives, and are doing so on a voluntary basis. These environmental initiatives include the utilization of alternative energy, sustainable building design, retrofitting energy efficient technology to existing facilities, water conservation, recycling programs, and construction waste management. Motivators, priorities, and barriers to airport sustainable practices are identified to provide insight to current and future environmental trends at airports. The results of this research study identify a need for official publications that can be utilized by airports wishing to invest in sustainable initiatives. Further research is necessary by the federal government to create a user-friendly guide for airport sustainability that can be utilized by large and small airports alike

    Can we have allergen-free foods?

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    Biotechnology can be used to reduce allergenicity. Much attention has been focused on the possibility that modification of foods through recombinant DNA technology could unintentionally introduce new allergens but developers and regulators take steps to assess allergenicity of novel proteins. However it is also possible to reduce allergenicity of foods by determining which proteins are responsible for the allergic reaction and then to alter them so that they no longer trigger an immune response in sensitive individuals. While it may not be possible to alter all of the allergenic proteins in some foods, there is potential to open up a whole new range of foods for those who cannot consume them now

    “Radar-A-Thon” Concept Paper: RAPHAEL COTS Radar

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    This paper presents a low-cost X-band FMCW radar system suitable for short range sensing in an indoor environment. The design is based on a PLL-VCO architecture, and is realised as a direct conversion receiver. It can achieve range resolutions of 30 cm or 10 cm in standard and ultra- wideband modes respectively. The system is capable of producing programmable linear sweeps over wide bandwidths, and is compliant with FCC Part 15

    Contemporary outcomes of continuous-flow biventricular assist devices.

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    BACKGROUND: Significant right ventricular failure (RVF) complicating left ventricular assist device (LVAD) placement has been reported at 10–30%. Although primarily indicated for left ventricular failure, ventricular assist devices (VADs) have become utilized in a biventricular setup to combat right ventricular failure (RVF) following LVAD implantation. With the advent of continuous-flow LVADs (CF-LVADs) superseding their pulsatile predecessors, the shift towards CF-biventricular assist devices (CF-BiVADs) come with the prospect of improved outcomes over previous pulsatile BiVADs. We aim to review the literature and determine the outcomes of CF-BiVAD recipients. METHODS: A systematic review was performed to determine the outcomes of CF-BiVADs. Pre-operative demographics and device configuration data was collected. Primary outcomes evaluated were short-term survival, long-term survival, duration of support, and survival to transplant. Secondary outcomes evaluated included intensive care unit (ICU) and hospital length of stay (ICU-LOS and HLOS, respectively), pump thrombosis, pump exchange. Median and interquartile range was reported where appropriate. A major limitation was the likely overlap of cohorts across publications, which may have contributed to some selection bias. RESULTS: Of 1,282 screened, 12 publications were evaluated. Sample size ranged from 4 to 93 CF-BiVAD recipients, and follow-up ranged from 6 to 24 months. Mean age ranged from 34 to 52 years old. Forty-five percent of CF-BiVADs had right atrial (RA-) inflow cannulation, with the remaining being right ventricular (RV). Thirty-day survival was a median of 90% (IQR 82–97.8%) and 12-month survival was a median of 58.5% (IQR 47.5–62%). Where reported, rate of pump thrombosis (predominantly the right VAD) was a median of 31% (IQR 14–36%), although pump exchange was only 9% (IQR 1.5–12.5%). CONCLUSIONS: RVF post-LVAD implantation is a high morbidity and mortality complication. There is no on-label continuous-flow RVAD currently available. Thus, the modifications of LVADs for right ventricular support to combat pump thrombosis has resulted in various techniques. BiVAD recipients are predominantly transplant candidates, and complications of pump thrombosis and driveline infection whilst on wait-list are of great consequence. This study demonstrates the need for an on-label CF-BiVAD

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/97166/1/jfo12080.pd

    The striatal dopamine transporter in first-episode, drug-naive schizophrenic patients: evaluation by the new SPECT-ligand[99mTc]TRODAT-1

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    Following the current hypothesis that acute schizophrenic psychotic illness is associated with a triatal ‘hyperdopaminergic state’, presynaptic integrity and dopamine transporter (DAT) density in first-episode, neuroleptic-naive schizophrenic patients was measured by single-photonemission- tomography (SPECT) and compared with that in healthy control subjects. A new SPECT-ligand for assessment of the striatal DAT, the Technetium-99m-labelled tropane TRODAT-1 ([99mTc]TRODAT-1), was used. Ten inpatients suffering from a first acute schizophrenic episode and 10 age- and sex-matched healthy control subjects underwent SPECT with [99mTc]TRODAT-1. On the day of SPECT, psychopathological ratings were performed with the Brief Psychiatric Rating Scale (BPRS), the Positive and Negative Syndrome Scale (PANSS) and Schedule for Assessment of Negative Symptoms (SANS). Patients had not previously received any neuroleptic or antidepressant medication. Mean specific TRODAT-1 binding in the striatum did not differ significantly between the patient and the age- and sex-matched control group (1.25 vs. 1.28). Variance was significantly higher in the patient group. The data obtained with the new ligand in first-episode, drug-naive schizophrenic patients are in line with the PET results from the group of Laakso et al. in a comparable patient sample. [99mTc]TRODAT-1 seems to be a valuable new SPECTligand in the evaluation of the presynaptic site of the striatal dopaminergic synapse in schizophrenia

    A comparative study of arbitration algorithms for the Alpha 21364 pipelined router

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    Interconnection networks usually consist of a fabric of interconnected routers, which receive packets arriving at their input ports and forward them to appropriate output ports. Unfortunately, network packets moving through these routers are often delayed due to conflicting demand for resources, such as output ports or buffer space. Hence, routers typically employ arbiters that resolve conflicting resource demands to maximize the number of matches between packets waiting at input ports and free output ports. Efficient design and implementation of the algorithm running on these arbiters is critical to maximize network performance.This paper proposes a new arbitration algorithm called SPAA (Simple Pipelined Arbitration Algorithm), which is implemented in the Alpha 21364 processor's on-chip router pipeline. Simulation results show that SPAA significantly outperforms two earlier well-known arbitration algorithms: PIM (Parallel Iterative Matching) and WFA (Wave-Front Arbiter) implemented in the SGI Spider switch. SPAA outperforms PIM and WFA because SPAA exhibits matching capabilities similar to PIM and WFA under realistic conditions when many output ports are busy, incurs fewer clock cycles to perform the arbitration, and can be pipelined effectively. Additionally, we propose a new prioritization policy called the Rotary Rule, which prevents the network's adverse performance degradation from saturation at high network loads by prioritizing packets already in the network over new packets generated by caches or memory.Mukherjee, S.; Silla Jiménez, F.; Bannon, P.; Emer, J.; Lang, S.; Webb, D. (2002). A comparative study of arbitration algorithms for the Alpha 21364 pipelined router. ACM SIGPLAN Notices. 37(10):223-234. doi:10.1145/605432.605421S223234371

    ENZYME ENGINEERING AT ALMAC: Case studies of enzyme discovery and engineering

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