Bioenergetics of the freshwater prosobranch Idiopoma angularis Muller in Laguna de Bay

This study was made as an attempt to investigate some of the ecological aspects of the freshwater snail Idiopoma angularis Muller in a modern framework of energy flow and mathematical models. It offers the first investigation of respiration (as related to temperature and body size), production (growth), and excretion in the prosobranch I. angularis in Laguna Lake

Design, synthesis, and evaluation of curcumin-derived arylheptanoids for glioblastoma and neuroblastoma cytotoxicity

Using an innovative approach toward multiple carbon-carbon bond-formations that relies on the multifaceted catalytic properties of titanocene complexes we constructed a series of C1-C7 analogs of curcumin for evaluation as brain and peripheral nervous system anti-cancer agents. C2-Arylated analogs proved efficacious against neuroblastoma (SK-N-SH & SK-N-FI) and glioblastoma multiforme (U87MG) cell lines. Similar inhibitory activity was also evident in p53 knockdown U87MG GBM cells. Furthermore, lead compounds showed limited growth inhibition in vitro against normal primary human CD34+hematopoietic progenitor cells. Taken together, the present findings indicate that these curcumin analogs are viable lead compounds for the development of new central and peripheral nervous system cancer chemotherapeutics with the potential for little effects on normal hematopoietic progenitor cells

The first case of Brucella canis in Sweden: background, case report and recommendations from a northern European perspective

Infection with Brucella canis has been diagnosed in Sweden for the first time. It was diagnosed in a three-year-old breeding bitch with reproductive disturbances. Fifteen in-contact dogs were tested repeatedly and all of them were negative for B. canis. The source of infection could not be defined. The present article describes the case and the measures undertaken and gives a short review over B. canis. Recommendations on how to avoid the infection in non-endemic countries are given

Limnological features of Lake Buluan: Preliminary findings and observations

A limnological survey of Lake Buluan in Mindanao was conducted to evaluate its potentials for fishpen and fish cage culture. The lake was found to be shallow and highly productive, with the major physicochemical and biological parameters within ranges favorable for fish production. The lake has high gross primary production values attributable to high densities of phytoplankton, primarily blue-green algae. It has a high annual yield of 10,000 mt of fish, which when divided by its area of 6,000 hectares, gives an average production of 1.64 mt/ha/yr - the highest open water catch in the Philippines and in Southeast Asia today

Shop ‘til you drop: Examining the impact of risk and trust in m-commerce and its subsequent effects on consumers’ future purchase intention

This study examines the impact of Risk and Trust on consumers’ Future Purchase Intention whilst focusing on the antecedents of the former in an attempt to explain how and why the aforementioned variables interact in the way they do. Several moderating variables that reflect phenomena specific to the Philippines M-Commerce market have also been employed to measure its impact on the overall model. The data for this study was obtained using a survey instrument distributed to MCommerce users within Metro Manila using a Snowball Sampling procedure. Results of this survey were then subjected to a regression analysis in order to measure the basal impact of Risk, Trust, and its antecedents on consumers’ Future Purchase Intention. In lieu with this, a Moderated Mediation Regression Analysis was employed in order to quantify the impact of the study’s moderating and mediating variables on the overall model. Results of this process revealed that all the moderating variables employed in this study were found to be invalid moderators, thus implying a non-significant effect on the relationship between Risk, Trust, and its respective antecedents. Risk and its antecedents were also found to have a non-significant effect on the consumers’ Future Purchase Intention, whilst Trust and its antecedents were found to exhibit the opposite. While the latter is an outcome that was expected from the study, the non-significance of Risk and its antecedents oppose the researchers’ a priori expectations, which can be attributed to the volatility of the economic environment of the Philippines while the survey instrument was being distributed. As such, the in-depth results to this study can provide notable insights on the workings of the Philippine M-Commerce industry, as well as a clearer portrait of the typical Filipino M-Consumer, supplying reasons behind their purchasing behaviors during tumultuous periods in time