Using the Dipolar and Quadrupolar Moments to Improve Solar-Cycle Predictions Based on the Polar Magnetic Fields

The solar cycle and its associated magnetic activity are the main drivers behind changes in the interplanetary environment and Earth's upper atmosphere (commonly referred to as space weather and climate). In recent years there has been an effort to develop accurate solar cycle predictions, leading to nearly a hundred widely spread predictions for the amplitude of solar cycle 24. Here we show that cycle predictions can be made more accurate if performed separately for each hemisphere, taking advantage of information about both the dipolar and quadrupolar moments of the solar magnetic field during minimum

Reconfiguración asimétrica de un manipulador paralelo de 3-gdl

In this paper an asymmetric reconfigurable parallel manipulator is presented. Asymmetric configurations are obtained by modifying the angle between each of the kinematic chains. Thanks to the reconfiguration proposal significant improvement of the manipulator performance can be obtained with respect to a Delta-type parallel robot. The computation of the best condition number is obtained, the results show that by using the redundancy, all the performance indices that depend on the Jacobian matrix can be improved as well.En este trabajo se presenta un manipulador paralelo reconfigurable asimétrico. Al modificar los ángulos de cada una de las cadenas cinemáticas pueden obtenerse configuraciones asimétricas. Gracias a la reconfiguración propuesta pueden generarse mejoras significativas del desempeño del manipulador, con respecto a un robot paralelo tipo Delta. El cálculo del mejor número de condición es obtenido, los resultados muestran que usando la redundancia todos los índices de desempeño que dependen de la matriz Jacobiana pueden ser mejorados también

Estimating the mass of CMEs from the analysis of EUV dimmings

Context. Reliable estimates of the mass of coronal mass ejections (CMEs) are required to quantify their energy and predict how they affect space weather. When a CME propagates near the observer's line of sight, these tasks involve considerable errors, which motivated us to develop alternative means for estimating the CME mass. Aims. We aim at further developing and testing a method that allows estimating the mass of CMEs that propagate approximately along the observer's line of sight. Methods. We analyzed the temporal evolution of the mass of 32 white-light CMEs propagating across heliocentric heights of 2.5-15 R, in combination with that of the mass evacuated from the associated low coronal dimming regions. The mass of the white-light CMEs was determined through existing methods, while the mass evacuated by each CME in the low corona was estimated using a recently developed technique that analyzes the dimming in extreme-UV (EUV) images. The combined white-light and EUV analyses allow the quantification of an empirical function that describes the evolution of CME mass with height. Results. The analysis of 32 events yielded reliable estimates of the masses of front-side CMEs. We quantified the success of the method by calculating the relative error with respect to the mass of CMEs determined from white-light STEREO data, where the CMEs propagate close to the plane of sky. The median for the relative error in absolute values is ≈30%; 75% of the events in our sample have an absolute relative error smaller than 51%. The sources of uncertainty include the lack of knowledge of piled-up material, subsequent additional mass supply from the dimming region, and limitations in the mass-loss estimation from EUV data. The proposed method does not rely on assumptions of CME size or distance to the observer's plane of sky and is solely based on the determination of the mass that is evacuated in the low corona. It therefore represents a valuable tool for estimating the mass of Earth-directed events.Fil: López, F. M.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan. Instituto de Ciencias Astronómicas, de la Tierra y del Espacio. Universidad Nacional de San Juan. Instituto de Ciencias Astronómicas, de la Tierra y del Espacio; ArgentinaFil: Cremades Fernandez, Maria Hebe. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Tecnológica Nacional; ArgentinaFil: Balmaceda, Laura Antonia. George Mason University; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan. Instituto de Ciencias Astronómicas, de la Tierra y del Espacio. Universidad Nacional de San Juan. Instituto de Ciencias Astronómicas, de la Tierra y del Espacio; ArgentinaFil: Nuevo, Federico Alberto. Consejo Nacional de Investigaciónes Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Astronomía y Física del Espacio. - Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Astronomía y Física del Espacio; ArgentinaFil: Vásquez, A. M.. Consejo Nacional de Investigaciónes Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Astronomía y Física del Espacio. - Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Astronomía y Física del Espacio; Argentina. Universidad Nacional de Tres de Febrero; Argentin

Families of Association Schemes on Triples from Two-Transitive Groups

Association schemes on triples (ASTs) are ternary analogues of classical association schemes. Analogous to Schurian association schemes, ASTs arise from the actions of two-transitive groups. In this paper, we obtain the sizes and third valencies of the ASTs obtained from the two-transitive permutation groups by determining the orbits of the groups' two-point stabilizers. Specifically, we obtain these parameters for the ASTs obtained from the actions of $S_n$ and $A_n$, $PGU(3,q)$, $PSU(3,q)$, and $Sp(2k,2)$, $Sz(2^{2k+1})$ and $Ree(3^{2k+1})$, some subgroups of $A\Gamma L(k,n)$, some subgroups of $P\Gamma L(k,n)$, and the sporadic two-transitive groups. Further, we obtain the intersection numbers for the ASTs obtained from these subgroups of $P\Gamma L(k,n)$ and $A \Gamma L(k,n)$, and the sporadic two-transitive groups. In particular, the ASTs from these projective and sporadic groups are commutative.Comment: 20 pages, 5 table

The Minimum of Solar Cycle 23: As Deep as It Could Be?

In this work we introduce a new way of binning sunspot group data with the purpose of better understanding the impact of the solar cycle on sunspot properties and how this defined the characteristics of the extended minimum of cycle 23. Our approach assumes that the statistical properties of sunspots are completely determined by the strength of the underlying large-scale field and have no additional time dependencies. We use the amplitude of the cycle at any given moment (something we refer to as activity level) as a proxy for the strength of this deep-seated magnetic field. We find that the sunspot size distribution is composed of two populations: one population of groups and active regions and a second population of pores and ephemeral regions. When fits are performed at periods of different activity level, only the statistical properties of the former population, the active regions, is found to vary. Finally, we study the relative contribution of each component (small-scale versus large-scale) to solar magnetism. We find that when hemispheres are treated separately, almost every one of the past 12 solar minima reaches a point where the main contribution to magnetism comes from the small-scale component. However, due to asymmetries in cycle phase, this state is very rarely reached by both hemispheres at the same time. From this we infer that even though each hemisphere did reach the magnetic baseline, from a heliospheric point of view the minimum of cycle 23 was not as deep as it could have been

Economic evaluation of sunitinib versus pazopanib and best supportive care for the treatment of metastatic renal cell carcinoma in Chile: cost-effectiveness analysis and a mixed treatment comparison

© 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group. Background: Sunitinib and Pazopanib are two metastatic renal cell carcinoma (MRCC) treatment alternatives, however the health system in Chile does not consider coverage for any. The cost-effectiveness versus relevant comparator was assessed to support evidence-based decision making. Methods: A four health states Markov model was built: first, second line treatments, BSC and death. Benefits were measured in QALYs, and efficacy estimates were obtained from an indirect treatment comparison. A 10-year time horizon and a 3% undifferentiated discount rate were considered. Deterministic and probabilistic sensitivity analyses were performed. Results: The costs of treating MRCC with Sunitinib were higher than Pazopanib and BSC. When comparing Sunitinib versus Pazopanib, the incremental benefit is small favoring Sunitinib (0.03 QALYs). The base case scenario shows an average ICER of PA versus BSC of US$62,327.11/QALY and of US$85,885/QALY for Sunitinib versus Pazopanib. The ICER was most sensitive to the OS relative to BSC, where evidence was associated to important bias. Conclusions: Sunitinib or Pazopanib can be considered cost-effective if a 3 GDP per-capita threshold is assumed. The decision between SU or PA is highly sensitive to the price of the drugs, rather than the outcomes. Therefore, the decision might be made based on cost-minimization exercise