1,919 research outputs found
Cosmic evolution of extragalactic C 1, C 2, and CO luminosity
Carbon is the fourth most abundant element in the Galaxy with an abundance of approximately 4 x 10(exp -4) relative to hydrogen. Of all abundant metals it is the easiest to observe in the interstellar medium (ISM). Carbon can be found in four dominant forms: dust grains, C 2, C 1, and CO. The latter is the most abundant molecule (next to H2) in molecular clouds. All three gas-phase forms produce strong sub-mm wavelength emission lines and are the principal tracers of the warm and dense neutral phases of the ISM. We calculate the gas-phase abundances of neutral carbon (C 1), ionized carbon (C 2), and carbon monoxide (CO) as a function of cosmic time or redshift z in an idealized scenario of galactic evolution
Cleaning up Eta Carinae: Detection of Ammonia in the Homunculus
We report the first detection of ammonia in the Homunculus nebula around eta
Carinae, which is also the first detection of emission from a polyatomic
molecule in this or any other luminous blue variable (LBV) nebula. Observations
of the NH3 (J,K)=(3,3) inversion transition made with the Australia Telescope
Compact Array reveal emission at locations where infrared H2 emission had been
detected previously, near the strongest dust emission in the core of the
Homunculus. We also detect ammonia emission from the so-called ``strontium
filament'' in the equatorial disk. The presence of NH3 around eta Car hints
that molecular shells around some Wolf-Rayet stars could have originated in
prior LBV eruptions, rather than in cool red supergiant winds or the ambient
interstellar medium. Combined with the lack of any CO detection, NH3 seems to
suggest that the Homunculus is nitrogen rich like the ionized ejecta around eta
Car. It also indicates that the Homunculus is a unique laboratory in which to
study unusual molecule and dust chemistry, as well as their rapid formation in
a nitrogen-rich environment around a hot star. We encourage future observations
of other transitions like NH3 (1,1) and (2,2), related molecules like N2H+, and
renewed attempts to detect CO.Comment: 4 pages, accepted to ApJ letter
Genetic analysis of multiple fruit quality traits in mango across sites and years
A key strategy to improve fruit quality and consumer appeal in mangoes is to breed trait improvements into new cultivars. There are several key fruit quality traits in mango. Knowledge of the heritability and relationship among these traits is important for breeding success. This paper implements a linear mixed model analysis including paternal information for analysis of 13 important fruit quality traits from mango cultivars planted across three environments and assessed over several seasons. The traits analysed were average fruit weight, skin background colour, blush colour, percentage blush, blush intensity, skin thickness, beak shape, stem-end shape, deformities, mesocarp colour, mesocarp texture, seed width and mesocarp recovery. The analysis allows investigation into trait heritabilities and stability of traits over years and sites, as well as genetic correlations among traits
SU(6) Gauge-Higgs Grand Unification: Minimal Viable Models and Flavor
Gauge-Higgs grand unification theories are models of gauge-Higgs unification that extend the electroweak group into a simple group that includes the color symmetry. The minimal option is a gauge-Higgs grand unification based on the SU(6) gauge group, mirroring SU(5) grand unification in 4D while providing a solution to the hierarchy problem. We explore different minimal and realistic novel incarnations of SU(6) gauge-Higgs grand unification. We submit the setup to the various flavor hierarchies observed in nature and, utilizing the power of the fifth dimension, identify an embedding that provides a compelling model of quarks and leptons that naturally explains the mass hierarchies and the CKM/PMNS structure. We perform a detailed study of quark - and lepton - flavor constraints (which are intimately related due to the GUT nature) together with an analysis of the Higgs potential which arises at the loop level. Electroweak precision constraints on the model are discussed and the rich scalar sector is analyzed. Future flavor constraints from upcoming experiments will provide a stringent test for this class of models, while a scalar singlet and leptoquark provide unique targets for current and future collider experiments to probe this solution to various open questions in nature
Toward Integration of mHealth in Primary Care in the Netherlands: A Qualitative Analysis of Stakeholder Perspectives
Background: There is a growing need to structurally change the way chronic illness care is organized as health systems struggle to meet the demand for chronic care. mHealth technologies can alter traditional approaches to health care provision by stimulating self-management of chronically ill patients. The aim of this study was to understand the complex environment related to the introduction of mHealth solutions into primary care for chronic disease management while considering health system functioning and stakeholder views. Methods: A transdisciplinary approach was used informed by the Interactive Learning and Action (ILA) methodology. Exploratory interviews (n = 5) were held with representatives of stakeholder groups to identify and position key stakeholders. Subsequently, professionals and chronically ill patients were consulted separately to elaborate on the barriers and facilitators in integration, using semi-structured interviews (n = 17) and a focus group (n = 6). Follow-up interviews (n = 5) were conducted to discuss initial findings of the stakeholder analysis. Results: Most stakeholders, in particular primary care practitioners and patients, seem to have a supporting or mixed attitude toward integration of mHealth. On the other hand, several powerful stakeholders, including primary care information system developers and medical specialists are likely to show resistance or a lack of initiative toward mHealth integration. Main barriers to mHealth integration were a lack of interoperability with existing information systems; difficulties in financing mHealth implementation; and limited readiness in general practices to change. Potential enablers of integration included co-design of mHealth solutions and incentives for pioneers. Conclusion: Stakeholders acknowledge the benefits of integrating mHealth in primary care. However, important barriers perceived by end-users prevent them to fully adopt and use mHealth. This study shows that the complexity of introducing mHealth into primary care calls for strategies encouraging collaboration between multiple stakeholders to enhance successful implementation
The Potential and Challenges of siRNA-Based Targeted Therapy for Treatment of Patients with Glioblastoma
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