331 research outputs found

    Instrumentation status of the low-b magnet systems at the Large Hadron Collider (LHC)

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    The low-beta magnet systems are located in the Large Hadron Collider (LHC) insertion regions around the four interaction points. They are the key elements in the beams focusing/defocusing process allowing proton collisions at luminosity up to 10**34/cm**2s. Those systems are a contribution of the US-LHC Accelerator project. The systems are mainly composed of the quadrupole magnets (triplets), the separation dipoles and their respective electrical feed-boxes (DFBX). The low-beta magnet systems operate in an environment of extreme radiation, high gradient magnetic field and high heat load to the cryogenic system due to the beam dynamic effect. Due to the severe environment, the robustness of the diagnostics is primordial for the operation of the triplets. The hardware commissioning phase of the LHC was completed in February 2010. In the sake of a safer and more user-friendly operation, several consolidations and instrumentation modifications were implemented during this commissioning phase. This paper presents the instrumentation used to optimize the engineering process and operation of the final focusing/defocusing quadrupole magnets for the first years of operation.Comment: 6 pp. ICEC 23 - ICMC 2010 International Cryogenic Engineering Conference 23 - International Cryogenic Materials Conference 2010. 19-23 Jul 2010. Wroclaw, Polan

    Dynamical mechanism of anticipating synchronization in excitable systems

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    We analyze the phenomenon of anticipating synchronization of two excitable systems with unidirectional delayed coupling which are subject to the same external forcing. We demonstrate for different paradigms of excitable system that, due to the coupling, the excitability threshold for the slave system is always lower than that for the master. As a consequence the two systems respond to a common external forcing with different response times. This allows to explain in a simple way the mechanism behind the phenomenon of anticipating synchronization.Comment: 4 pages including 7 figures. Submitted for publicatio

    Optogenetic Interrogation of Functional Synapse Formation by Corticospinal Tract Axons in the Injured Spinal Cord

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    To restore function after injury to the CNS, axons must be stimulated to extend into denervated territory and, critically, must form functional synapses with appropriate targets. We showed previously that forced overexpression of the transcription factor Sox11 increases axon growth by corticospinal tract (CST) neurons after spinal injury. However, behavioral outcomes were not improved, raising the question of whether the newly sprouted axons are able to form functional synapses. Here we developed an optogenetic strategy, paired with single-unit extracellular recordings, to assess the ability of Sox11-stimulated CST axons to functionally integrate in the circuitry of the cervical spinal cord. Initial time course experiments established the expression and function of virally expressed Channelrhodopsin (ChR2) in CST cell bodies and in axon terminals in cervical spinal cord. Pyramidotomies were performed in adult mice to deprive the left side of the spinal cord of CST input, and the right CST was treated with adeno-associated virus (AAV)–Sox11 or AAV–EBFP control, along with AAV–ChR2. As expected, Sox11 treatment caused robust midline crossing of CST axons into previously denervated left spinal cord. Clear postsynaptic responses resulted from optogenetic activation of CST terminals, demonstrating the ability of Sox11-stimulated axons to form functional synapses. Mapping of the distribution of CST-evoked spinal activity revealed overall similarity between intact and newly innervated spinal tissue. These data demonstrate the formation of functional synapses by Sox11-stimulated CST axons without significant behavioral benefit, suggesting that new synapses may be mistargeted or otherwise impaired in the ability to coordinate functional output. SIGNIFICANCE STATEMENT As continued progress is made in promoting the regeneration of CNS axons, questions of synaptic integration are increasingly prominent. Demonstrating direct synaptic integration by regenerated axons and distinguishing its function from indirect relay circuits and target field plasticity have presented technical challenges. Here we force the overexpression of Sox11 to stimulate the growth of corticospinal tract axons in the cervical spinal cord and then use specific optogenetic activation to assess their ability to directly drive postsynaptic activity in spinal cord neurons. By confirming successful synaptic integration, these data illustrate a novel optogenetic-based strategy to monitor and optimize functional reconnection by newly sprouted axons in the injured CNS

    Private Aggregation from Fewer Anonymous Messages

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    Consider the setup where nn parties are each given a number xiFqx_i \in \mathbb{F}_q and the goal is to compute the sum ixi\sum_i x_i in a secure fashion and with as little communication as possible. We study this problem in the anonymized model of Ishai et al. (FOCS 2006) where each party may broadcast anonymous messages on an insecure channel. We present a new analysis of the one-round "split and mix" protocol of Ishai et al. In order to achieve the same security parameter, our analysis reduces the required number of messages by a Θ(logn)\Theta(\log n) multiplicative factor. We complement our positive result with lower bounds showing that the dependence of the number of messages on the domain size, the number of parties, and the security parameter is essentially tight. Using a reduction of Balle et al. (2019), our improved analysis of the protocol of Ishai et al. yields, in the same model, an (ε,δ)\left(\varepsilon, \delta\right)-differentially private protocol for aggregation that, for any constant ε>0\varepsilon > 0 and any δ=1poly(n)\delta = \frac{1}{\mathrm{poly}(n)}, incurs only a constant error and requires only a constant number of messages per party. Previously, such a protocol was known only for Ω(logn)\Omega(\log n) messages per party.Comment: 31 pages; 1 tabl

    Influence of Thermal Cycling on Cryogenic Thermometers

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    The stringent requirements on temperature control of the superconducting magnets for the Large Hadron Collider (LHC), impose that the cryogenic temperature sensors meet compelling demands such as long-term stability, radiation hardness, readout accuracy better than 5 mK at 1.8 K and compatibility with industrial control equipment. This paper presents the results concerning long-term stability of resistance temperature sensors submitted to cryogenic thermal cycles. For this task a simple test facility has been designed, constructed and put into operation for cycling simultaneously 115 cryogenic thermometers between 300 K and 4.2 K. A thermal cycle is set to last 71/4 hours: 3 hours for either cooling down or warming up the sensors and 1 respectively 1/4 hour at steady temperature conditions at each end of the temperature cycle. A Programmable Logic Controller (PLC) drives automatically this operation by reading 2 thermometers and actuating on 3 valves and 1 heater. The first thermal cycle was accomplished in a temperature calibration facility and all the thermometers were recalibrated again after 10, 25 and 50 cycles. Care is taken in order not to expose the sensing elements to moisture that can reputedly affect the performance of some of the sensors under investigation. The temperature sensors included Allen-Bradley and TVO carbon resistors, Cernox, thin-film germanium, thin-film and wire-wound Rh-Fe sensors

    Instrumentation, Field Network And Process Automation for the LHC Cryogenic Line Tests

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    This paper describes the cryogenic control system and associated instrumentation of the test facility for 3 pre-series units of the LHC Cryogenic Distribution Line. For each unit, the process automation is based on a Programmable Logic Con-troller implementing more than 30 closed control loops and handling alarms, in-terlocks and overall process management. More than 160 sensors and actuators are distributed over 150 m on a Profibus DP/PA network. Parameterization, cali-bration and diagnosis are remotely available through the bus. Considering the diversity, amount and geographical distribution of the instru-mentation involved, this is a representative approach to the cryogenic control system for CERN's next accelerator

    Discontinuous Transition from a Real Bound State to Virtual Bound State in a Mixed-Valence State of SmS

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    Golden SmS is a paramagnetic, mixed-valence system with a pseudogap. With increasing pressure across a critical pressure Pc, the system undergoes a discontinuous transition into a metallic, anti-ferromagnetically ordered state. By using a combination of thermodynamic, transport, and magnetic measurements, we show that the pseudogap results from the formation of a local bound state with spin singlet. We further argue that the transition Pc is regarded as a transition from an insulating electron-hole gas to a Kondo metal, i.e., from a spatially bound state to a Kondo virtually bound state between 4f and conduction electrons.Comment: 5 pages, 5 figure

    Outcome of the Commissioning of the Readout and Actuation Channels for the Cryogenics of the LHC

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    The LHC is the largest cryogenic installation ever built. For its operation more than 14 000 sensors and actuators are required. The 27 km circumference of the accelerator is divided into 8 sectors: like for the rest of the hardware and in particular the cryogenics, the commissioning of the cryogenics instrumentation has been performed sector by secto

    Instrumentation, Field Network and Process Automation for the Cryogenic System of the LHC Test String

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    CERN is now setting up String 2, a full-size prototype of a regular cell of the LHC arc. It is composed of two quadrupole, six dipole magnets, and a separate cryogenic distribution line (QRL) for the supply and recovery of the cryogen. An electrical feed box (DFB), with up to 38 High Temperature Superconducting (HTS) leads, powers the magnets. About 700 sensors and actuators are distributed along four Profibus DP and two Profibus PA field buses. The process automation is handled by two controllers, running 126 Closed Control Loops (CCL). This paper describes the cryogenic control system, associated instrumentation, and their commissioning
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