Child Development Center- Fire Protection Analysis

This report contains two separate forms of analysis, Prescriptive-Based Analysis and Performance-Base Analysis. The Prescriptive Analysis discusses an overview of the building and its features whereas the Performance-Based Analysis discusses the building meeting applicable codes and standards as discussed in NFPA 101 Life Safety Code 2012 Edition, Unified Facilities Code (UFC), International Building Code (IBC) 2012 Edition, and the SFPE Handbook of Fire Protection Engineering. The Child Development Center (CDC) was analyzed as a new construction building. There are also noted assumptions within the report where necessary information about the building could not be obtained due to information restrictions from the Government. The building discussed in this report is the Child Development Center (CDC) located in an area titled Murphy Canyon on Naval Base San Diego. Due to the nature of the building and the citizens that utilize it, Common Access Cards (CAC) are required when visiting the building. The CDC is initially considered a Group I-4 Occupancy, but can be labeled as a Group E occupancy due to the building having egress exits in each classroom to the immediate outside. This building has no immediate adjacent building surrounding it. The prescriptive-based analysis within this document confirms that the building meets requirements of NFPA 101 Life Safety Code, NFPA 13, NFPA 17, NFPA 72, NFPA 92, Unified Facilities Code, and IBC. The report is also based on a CDC building expansion, which can be conducted at a later date. The performance-based analysis looks into the possibilities of fires arising in a staff break room. The software that aided this report for modeling each fire scenario is Fire Dynamics Simulator (FDS). The break room fire model involved a runaway coffee pot scenario that spreads to a polyurethane couch. In the event of a failure of the heat detection device located in the break room, the time from detection and notification by the quick response sprinkler would not allow enough time to instruct the occupants to leave the building before untenable conditions occurred. Also, the desired fire suppression system flow demand does not meet the requirement set at 2,000 gpm. The flow test to the building shows a flow rate that is approximately 40 gpm less than the 50% reduction flow rate of the desired 2,000 gpm system demand. One recommendation to the project building would be the installation of a fire pump. Due to the nature of the building owner and operator, limited pictures and as-built drawings could be taken due to security measures

S1NN GmbH & Co. KG (Automobile Connectivity Module 1.1)

The results of this report show how when diagnostics were run on the Connectivity Module 1.1, the problems discovered such as potential short-circuiting, 90-degree copper tracing angles, and components overheating/tombstoning were addressed. By using the method of “DMAIC,” which stands for Design, Measure, Analyze, Implement, Control, successful corrections were made. In the first design of the Printed Circuit Board (PCB), 1454 critical issues were found. With the newly designed PCB’s modifications being implemented, only 12 critical issues remained, which were later addressed and corrected. The results from this report are a functional Automobile Connectivity Module 1.1

Dominance Over N

Abstract.This paper provides an overview of the b-dominance order over the natural numbers, N, using the base b expansion of natural numbers. The b-dominance order is an accessible partially-ordered set that is less complex than the divisor relation but more complex than ≤; thus, it supplies a good medium through which an undergraduate can be exposed to the subject of order theory. Here we discuss many ideas in order theory, including the Poincaré polynomial and the Möbius function. Acknowledgements: The authors thank the M.J. Murdock Charitable Trust and the Pacific Lutheran University Division of Natural Sciences for their generous support. They would also like to extend their thanks to Dr. Tom Edgar for the project idea and all his help throughout their summer program. Page 24 RHIT Undergrad. Math. J., Vol. 14, no. 2

Dominance Over ℵ

This paper provides an overview of the b-dominance order over the natural numbers, ℵ, using the base b expansion of natural numbers. The b-dominance order is an accessible partially-ordered set that is less complex than the divisor relation but more complex than ≤; thus, it supplies a good medium through which an undergraduate can be exposed to the subject of order theory. Here we discuss many ideas in order theory, including the Poincare polynomial and the Mobius function

Caractérisation des flocs pour optimiser la floculation en amont de la filtration directe

Coagulation -- Cinétique de la floculation -- Caractérisation des flocs -- Comparison of two online flocculation monitoring techniques in predicting turbidity removal -- Mise à l'échelle des essais de filtration directe dans un pilote semi-industriel

Reading Between the Iron Lines: An Analysis of Cannon Arrangement on Caribbean Shipwrecks.

The aim of this study was to explore patterns of cannon distribution on shipwreck sites using primary historical sources and archaeological case studies. This archaeological data set comprised ten shipwreck sites with multiple cannons located in the Caribbean and in the waters of Bermuda. The intent was to determine signature characteristics of cannon patterns. These patterns may potentially reflect the wrecking event, crew procedure or emergency action jettisoning heavy artifacts during a time of disaster or post wrecking salvage operations. Historical sources revealed information concerning maritime insurance protocols for jettisoning artifacts

Employing a Modified Diffuser Momentum Model to Simulate Ventilation of the Orion CEV (DRAFT)

Computational Fluid Dynamics (CFD) is used to model the flow field in the Orion CEV cabin. The CFD model employs a momentum model used to account for the effect of supply grilles on the supply flow. The momentum model is modified to account for non-uniform velocity profiles at the approach of the supply grille. The modified momentum model is validated against a detailed vane-resolved model before inclusion into the Orion CEV cabin model. Results for this comparison, as well as that of a single ventilation configuration are presented

Water-Mediated Peptide Bond Formation in the Gas Phase: A Model Prebiotic Reaction

The emergence of life on the prebiotic Earth must have involved the formation of polypeptides, yet the polymerization of amino acids is thermodynamically unfavorable under biologically relevant aqueous conditions because amino acids are zwitterions in solution and because of the production of a water molecule through a condensation reaction. Many mechanisms for overcoming this thermodynamic unfavorability have been proposed, but the role of gas phase water clusters has not been investigated. We present the thermodynamics of the water-mediated gas phase dimerization reaction of glycine as a model for the atmospheric polymerization of amino acids prior to the emergence of biological machinery. We hypothesize that atmospheric aerosols may have played a major role in the prebiotic formation of peptide bonds by providing the thermodynamic driving force to facilitate increasingly stable linear oligopeptides. In addition, we hypothesize that small aerosols orient amino acids on their surfaces, thus providing the correct molecular orientations to funnel the reaction pathways of peptides through transition states that lead eventually to polypeptide products. Using density functional theory and a thorough configurational sampling technique, we show that the thermodynamic spontaneity of the linear dimerization of glycine in the gas phase can be driven by the addition of individual water molecules

Diagnosis and management of malignant peripheral nerve sheath tumors: Current practice and future perspectives

One of the most common malignancies affecting adults with the neurofibromatosis type 1 (NF1) cancer predisposition syndrome is the malignant peripheral nerve sheath tumor (MPNST), a highly aggressive sarcoma that typically develops from benign plexiform neurofibromas. Approximately 8-13% of individuals with NF1 will develop MPNST during young adulthood. There are few therapeutic options, and the vast majority of people with these cancers will die within 5 years of diagnosis. Despite efforts to understand the pathogenesis of these aggressive tumors, the overall prognosis remains dismal. This manuscript will review the current understanding of the cellular and molecular progression of MPNST, diagnostic workup of patients with these tumors, current treatment paradigms, and investigational treatment options. Additionally, we highlight novel areas of preclinical research, which may lead to future clinical trials. In summary, MPNST remains a diagnostic and therapeutic challenge, and future work is needed to develop novel and rational combinational therapy for these tumors

A 3D-Hybrid-Shot Spiral Sequence for Hyperpolarized 13^{13}C Imaging

Purpose: Hyperpolarized imaging experiments have conflicting requirements of high spatial, temporal, and spectral resolution. Spectral-Spatial RF excitation has been shown to form an attractive magnetization-efficient method for hyperpolarized imaging, but the optimum readout strategy is not yet known. Methods: In this work we propose a novel 3D hybrid-shot spiral sequence which features two constant density regions that permit the retrospective reconstruction of either high spatial or high temporal resolution images post hoc, (adaptive spatiotemporal imaging) allowing greater flexibility in acquisition and reconstruction. Results: We have implemented this sequence, both via simulation and on a pre-clinical scanner, to demonstrate its feasibility, in both a 1H phantom and with hyperpolarized 13C pyruvate in vivo. Conclusion: This sequence forms an attractive method for acquiring hyperpolarized imaging datasets, providing adaptive spatiotemporal imaging to ameliorate the conflict of spatial and temporal resolution, with significant potential for clinical translation