[¹¹C]PBR28 uptake (SUV) in eight different brain regions at 63 minutes after injection, for both rats and mice.

<p>The SUV values represent the average of the eight scans that were performed in both four rats and mice for the test-retest part of study, in which no arterial sampling was performed. * p<0.05.</p

V_T of [¹¹C]PBR28 in various brain structures in rats calculated using two-tissue compartment modelling (2-TCM) and Logan graphical analysis [16].

<p>V_T of [¹¹C]PBR28 in various brain structures in rats calculated using two-tissue compartment modelling (2-TCM) and Logan graphical analysis [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0125917#pone.0125917.ref016" target="_blank">16</a>].</p

Blood and plasma time activity curves (A), the percentage of [¹¹C]PBR28 in plasma (B) and the tissue-to-plasma ratio (C) in rats.

<p>Blood and plasma time activity curves (A), the percentage of [¹¹C]PBR28 in plasma (B) and the tissue-to-plasma ratio (C) in rats.</p

Correlation between V_T and SUV of [¹¹C]PBR28 in rats.

<p>Correlation between VT of [11C]PBR28 as calculated using two-tissue compartment modeling (2-TCM) (A+B) and Logan graphical analysis (C+D) [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0125917#pone.0125917.ref016" target="_blank">16</a>], and the SUV of [11C]PBR28, for the averages of eight brain regions (A+C) and for the individual values for each rats for the eight brain regions (B+D).</p

Test-retest variability (TRV) and interclass correlation coefficient (ICC) of [¹¹C]PBR28 for rats and mice that were scanned twice, with an interval of 7-days.

<p>Test-retest variability (TRV) and interclass correlation coefficient (ICC) of [¹¹C]PBR28 for rats and mice that were scanned twice, with an interval of 7-days.</p

Total brain time-activity curves of [¹¹C]PBR28 for rats and mice (SUV).

<p>The time-activity curves represent the average uptake of the eight scans that were performed in both four rats and mice for the test-retest part of study, in which no arterial sampling was performed.</p

Correlation between V_T obtained with two-tissue compartment modeling (2-TCM) and Logan analysis.

<p>Logan plots (A) and the correlation between V_<b>T</b> of [^<b>11</b>C]PBR28 as calculated using 2-TCM and Logan graphical analysis [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0125917#pone.0125917.ref016" target="_blank">16</a>], for the averages of eight brain regions (B) and for the individual values for each rats for the eight brain regions (C).</p

Representative PET images of a rat and a mouse of the test-retest part of the study, co-registered with the MRI scan.

<p>PET images of a representative rat and mouse are shown overlaying the individual MRI measurements.</p

Relazione del Consiglio all'Assemblea per l'approvazione del bilancio al 31.12.2003

Consiglio Nazionale delle Ricerche - Biblioteca Centrale - P.le Aldo Moro, 7, Rome / CNR - Consiglio Nazionale delle RichercheSIGLEITItal

Appendices A to G for “Study protocol: How does cognitive flexibility relate to other executive functions and learning in healthy young adults?”.

Appendices A to G for “Study protocol: How does cognitive flexibility relate to other executive functions and learning in healthy young adults?”.</p