Oncogenic senescence: a multi-functional perspective.

Cellular senescence is defined as an irreversible growth arrest with the acquisition of a distinctive secretome. The growth arrest is a potent anticancer mechanism whereas the secretome facilitates wound healing, tissue repair, and development. The senescence response has also become increasingly recognized as an important contributor to aging and age-related diseases, including cancer. Although oncogenic mutations are capable of inducing a beneficial senescence response that prevents the growth of premalignant cells and promotes cancer immune-surveillance, the secretome of senescent cells also includes factors with pro-tumorigenic properties. On June 23rd and 24th, 2016, the Division of Cancer Biology of the National Cancer Institute sponsored a workshop to discuss the complex role of cellular senescence in tumorigenesis with the goal to define the major challenges and opportunities within this important field of cancer research. Additionally, it was noted how the development of novel tools and technologies are required to accelerate research into a mechanistic understanding of senescent cells in carcinogenesis in order to overcome the current limitations in this exciting, yet ill-defined area

Mi Casa Es Su Casa: Supporting Student Created, Collaborative Learning Environments with LibGuides CMS

As faculty seek innovative ways to develop student-created, blended learning environments, librarians have an opportunity to provide technical tools, training, and support that enhances faculty-librarian collaboration and promotes library instructional services. LibGuides CMS provides a flexible platform for supporting student-created work, including student profiles, blogs, and simple html/scripting projects. This session discusses how librarians at Georgia Southern University opened up their LibGuides CMS platform to faculty in two programs to provide an online home for a variety of class and program-based projects. In each case, faculty and students were invited onto the platform as collaborative content creators and editors, while librarians provided instruction and technical support. In this way, the library directly enhanced teaching and learning with limited cost and minimal start-up time. During this session, presenters will discuss practical, pedagogical, and technical considerations related to these collaborations, with special emphasis on how LibGuides CMS supports the creation of customizable platforms for such work. Presenters will further address issues related to access control, discovery, and student privacy

Guides by the Side: The Role of Technical Services in Information Literacy Instruction

Presenters will explore the role of technical services in library instruction, specifically as this relates to the ACRL’s Framework for Information Literacy for Higher Education. This framework places emphasis on research as a highly contextual activity, where researcher practices and dispositions are linked to the communities of practice in which they occur. By extension, such communities exist and evolve semi-independently of any particular manifestation of library resources or services, meaning that libraries must be as prepared to accommodate autonomous practices and dispositions as they are to participate in shaping them. Technical services plays a significant role in determining how the library accommodates and shapes these practices and dispositions, which in turn impacts instruction. During this session, presenters will explore specific areas of overlap between technical and instructional services, especially with regard to selection, organization, and representation of resources to patrons. Presenters will then consider how collaboration across technical and instructional domains supports effective instruction, specifically within the context of the Framework. Presenters will invite participants to share their own experiences, and engage in brainstorming on how technical and instructional services personnel can work together to solve instructional challenges

Springshare Mashups: Repurposing Digital Content

How many research guides go neglected because we can’t keep up with all the stellar content we create for our patrons? As digital content producers, librarians are always looking for new ways to repurpose content for different audiences while streamlining content management. Fortunately, with the ongoing development of content management tools like Springshare LibGuides 2.0, the dream approaches reality. Presenters offer simple strategies (including naming, description, and chunking) for content creation and management that maximize opportunities for repurposing content across delivery platforms while keeping maintenance to a minimum. While this session focuses on LibGuides and LibAnswers, the content creation techniques discussed are applicable to any content management system that supports dynamic content mapping and/or external widget creation

Supporting Student-Led Content Creation in the Distance Learning Environment with LibGuides CMS

LibGuides CMS provides a flexible platform for supporting student-created work in the distance learning environment, including profiles, blogs, and html/scripting projects. This session explores how presenters opened up the LibGuides CMS platform to host collaboratively developed course content and student projects grounded in metaliteracy concepts embedded in the ACRL Framework for Information Literacy. Faculty and students are invited onto the platform as content creators and editors, while librarians provide instruction and technical support. Presenters will discuss practical, pedagogical, and technical considerations for supporting student-created content on LibGuides CMS, including access control and student privacy

Let the Right Ones In: Supporting Patrons as Content Creators with LibGuides and LibGuides CMS

With flexible access and permission features, LibGuides and LibGuides CMS offer an adaptable platform for hosting patron-created content. This paper highlights how librarians at Georgia Southern University opened their LibGuides CMS platform to host faculty and student projects and portfolios. Employing similar techniques, libraries can host a wide range of patron-created content while protecting library-managed guides and assets, controlling access to patron-created content, and protecting patron privacy. This paper provides a detailed overview of access and permission features available in LibGuides and LibGuides CMS, presents two case studies, and offers considerations and best practices for hosting patron-created content

Mi Casa Es Su Casa: Supporting Student-Created, Collaborative Learning Environments with LibGuides CMS

As faculty seek innovative ways to develop student-created, blended learning environments, librarians have an opportunity to provide technical tools, training, and support that enhances faculty-librarian collaboration and promotes library instructional services. LibGuides CMS provides a flexible platform for supporting student-created work, including student profiles, blogs, and simple html/scripting projects. This session discusses how librarians at Georgia Southern University opened up their LibGuides CMS platform to faculty in two programs to provide an online home for a variety of class and program-based projects. In each case, faculty and students were invited onto the platform as collaborative content creators and editors, while librarians provided instruction and technical support. In this way, the library directly enhanced teaching and learning with limited cost and minimal start-up time. During this session, presenters will discuss practical, pedagogical, and technical considerations related to these collaborations, with special emphasis on how LibGuides CMS supports the creation of customizable platforms for such work. Presenters will further address issues related to access control, discovery, and student privacy

Cellulosic biofuels: Expert views on prospects for advancement

In this paper we structure, obtain and analyze results of an expert elicitation on the relationship between U. S. government Research & Development funding and the likelihood of achieving advances in cellulosic biofuel technologies. While there was disagreement among the experts on each of the technologies, the patterns of disagreement suggest several distinct strategies. Selective Thermal Processing appears to be the most promising path, with the main question being how much funding is required to achieve success. Thus, a staged investment in this path looks promising. With respect to gasification, there remains fundamental disagreement over whether success is possible even at higher funding evels. Thus, basic research into the viability of the path makes sense. The Hydrolysis path induced the widest range of responses from the experts, indicating there may be value in collecting more information on this technology

Let the Right Ones In: Supporting Patrons as Content Creators with LibGuides and LibGuides CMS

LibGuides aren’t just for librarians anymore. With flexible access and permission features, LibGuides and LibGuides CMS each offer a flexible platform for hosting and supporting patron-created content. This poster highlights how, with a few simple configurations, librarians at a mid-sized university in the southeast opened up the LibGuides CMS platform to host student-developed projects and portfolios. Employing similar techniques, libraries can host a wide range of patron content, including blogs, group and event sites, and more. Learn how to extend editorial permissions to patrons while protecting your own guides and assets, as well as how to control access to patron-created content. This poster compares access and permission features available in LibGuides and LibGuides CMS. Also, privacy and policy considerations are addressed

Guides by the Side: The Role of Technical Services in Information Literacy Instruction

Presenters will explore the role of technical services in library instruction, specifically as this relates to the ACRL’s Framework for Information Literacy for Higher Education. This framework places emphasis on research as a highly contextual activity, where researcher practices and dispositions are linked to the communities of practice in which they occur. By extension, such communities exist and evolve semi-independently of any particular manifestation of library resources or services, meaning that libraries must be as prepared to accommodate autonomous practices and dispositions as they are to participate in shaping them. Technical services plays a significant role in determining how the library accommodates and shapes these practices and dispositions, which in turn impacts instruction. During this session, presenters will explore specific areas of overlap between technical and instructional services, especially with regard to selection, organization, and representation of resources to patrons. Presenters will then consider how collaboration across technical and instructional domains supports effective instruction, specifically within the context of the Framework. Presenters will invite participants to share their own experiences, and engage in brainstorming on how technical and instructional services personnel can work together to solve instructional challenges