Ondansetron does not inhibit the analgesic effect of alfentanil

5-Hydroxytryptamine (5-HT) causes antinociception via presynaptic 5-HT3 (5-HT subtype 3) receptors on primary afferent nociceptive neurones in the spinal cord dorsal horn. Therefore, ondansetron (a 5-HT3 receptor antagonist) may increase the perception of a noxious stimulus or decrease the effects of concurrently administered antinociceptive drugs. Using a randomized, doubleblind, crossover study design, we have tested this hypothesis in eight healthy volunteers who, on three different days, received either ondansetron and placebo, ondansetron and alfentanil or placebo and alfentanil. Experimental pain was induced with heat, cold, mechanical pressure and electrical stimulation. Ondansetron alone did not change the response to any of the experimental tests, but alfentanil and the combination ondansetron- alfentanil significantly changed the response compared with ondansetron alone. There was no difference between alfentanil alone and the combination ondansetron-alfentanil. We conclude that ondansetron does not change the response to pressure, heat, cold or electrical nociceptive stimuli or antagonize the analgesic effect of alfentani

Non BPS noncommutative vortices

We construct exact vortex solutions to the equations of motion of the Abelian Higgs model defined in non commutative space, analyzing in detail the properties of these solutions beyond the BPS point. We show that our solutions behave as smooth deformations of vortices in ordinary space time except for parity symmetry breaking effects induced by the non commutative parameter $\theta$.Comment: 17 pages, 5 figure

Tachyon Tube and Supertube

We search for tubular solutions in unstable D3-brane. With critical electric field E=1, solutions representing supertubes, which are supersymmetric bound states of fundamental strings, D0-branes, and a cylindrical D2-brane, are found and shown to exhibit BPS-like property. We also point out that boosting such a {\it tachyon tube} solution generates string flux winding around the tube, resulting in helical electric fluxes on the D2-brane. We also discuss issues related to fundamental string, absence of magnetic monopole, and finally more tachyon tubes with noncritical electric field.Comment: 21 pages, 3 figure

On critical behavior of phase transitions in certain antiferromagnets with complicated ordering

Within the four-loop \ve expansion, we study the critical behavior of certain antiferromagnets with complicated ordering. We show that an anisotropic stable fixed point governs the phase transitions with new critical exponents. This is supported by the estimate of critical dimensionality $N_c^C=1.445(20)$ obtained from six loops via the exact relation $N_c^C={1/2} N_c^R$ established for the real and complex hypercubic models.Comment: Published versio

Non-Abelian Chern-Simons Particles and their Quantization

A many--body Schr\"odinger equation for non--Abelian Chern--Simons particles is obtained from both point--particle and field--theoretic pictures. We present a particle Lagrangian and a field theoretic Lagrange density, and discuss their properties. Both are quantized by the symplectic method of Hamiltonian reduction. An $N$--body Schr\"odinger equation for the particles is obtained from both starting points. It is shown that the resulting interaction between particles can be replaced by non--trivial boundary conditions. Also, the equation is compared with the one given in the literature.Comment: 18 pages, MIT preprint CTP # 227

Critical behavior of certain antiferromagnets with complicated ordering: Four-loop \ve-expansion analysis

The critical behavior of a complex N-component order parameter Ginzburg-Landau model with isotropic and cubic interactions describing antiferromagnetic and structural phase transitions in certain crystals with complicated ordering is studied in the framework of the four-loop renormalization group (RG) approach in (4-\ve) dimensions. By using dimensional regularization and the minimal subtraction scheme, the perturbative expansions for RG functions are deduced and resummed by the Borel-Leroy transformation combined with a conformal mapping. Investigation of the global structure of RG flows for the physically significant cases N=2 and N=3 shows that the model has an anisotropic stable fixed point governing the continuous phase transitions with new critical exponents. This is supported by the estimate of the critical dimensionality $N_c=1.445(20)$ obtained from six loops via the exact relation $N_c={1/2} n_c$ established for the complex and real hypercubic models.Comment: LaTeX, 16 pages, no figures. Expands on cond-mat/0109338 and includes detailed formula

Forced Topological Nontrivial Field Configurations

The motion of a one-dimensional kink and its energy losses are considered as a model of interaction of nontrivial topological field configurations with external fields. The approach is based on the calculation of the zero modes excitation probability in the external field. We study in the same way the interaction of the t'Hooft-Polyakov monopole with weak external fields. The basic idea is to treat the excitation of a monopole zero mode as the monopole displacement. The excitation is found perturbatively. As an example we consider the interaction of the t'Hooft-Polyakov monopole with an external uniform magnetic field.Comment: 18 pages, 3 Postscript figures, RevTe

Matrix Models

Matrix models and their connections to String Theory and noncommutative geometry are discussed. Various types of matrix models are reviewed. Most of interest are IKKT and BFSS models. They are introduced as 0+0 and 1+0 dimensional reduction of Yang--Mills model respectively. They are obtained via the deformations of string/membrane worldsheet/worldvolume. Classical solutions leading to noncommutative gauge models are considered.Comment: Lectures given at the Winter School on Modern Trends in Supersymmetric Mechanics, March 2005 Frascati; 38p

Entanglement Entropy from a Holographic Viewpoint

The entanglement entropy has been historically studied by many authors in order to obtain quantum mechanical interpretations of the gravitational entropy. The discovery of AdS/CFT correspondence leads to the idea of holographic entanglement entropy, which is a clear solution to this important problem in gravity. In this article, we would like to give a quick survey of recent progresses on the holographic entanglement entropy. We focus on its gravitational aspects, so that it is comprehensible to those who are familiar with general relativity and basics of quantum field theory.Comment: Latex, 30 pages, invited review for Classical and Quantum Gravity, minor correction