730 research outputs found

    Lumpy capital adjustment and technical efficiency

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    This paper investigates the impact of lumpy capital adjustment on productivity at the firm level using data on Japanese manufacturing industries. We estimate stochastic production frontiers, taking firm heterogeneity into account. We find that investment spikes are negatively related to technical efficiency. Furtermore, we find a negative relationship between machinery capital age and measured efficiency.

    Vertical Ground Reaction Forces During Stair Descent Transition for Individuals with Femoroacetabular Impingement and Osteoarthritis

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    Femoroacetabular impingement (FAI) is a pathological condition characterized by the misshapen junction between the femoral head and acetabular rim causing joint friction. Not all individuals with FAI experience symptoms associated with the condition. Previous research has determined differences between those with and without symptomatic FAI (FAI-s) and those with and without osteoarthritis (OA) during stair ascent (Hammond et al., 2017 and Hall et al., 2017, respectively). No studies focused on stair descent ground reaction forces (GRFs) between individuals with FAI and/or OA exist. PURPOSE: This study analyzed key vertical GRF values during stair descent transition in adults with FAI-s, asymptomatic FAI (FAI-a) and OA. METHODS: Individuals were recruited by an orthopedic surgeon who used radiographs to assign group membership (FAI-s n=10, FAI-a n=11, OA n=10). Each person descended a 3-step staircase onto a Kistler force plate embedded into the floor (1000 Hz). The stair to floor transition was analyzed for three trials for each foot contact. Peak vertical impact and active forces (Fz1 and Fz2, respectively) were normalized by BW and the three trial average was analyzed. Dependent and independent t-tests were used to compare transition feet and groups (p \u3c 0.05). RESULTS: There were no differences for any group when comparing transition feet for Fz1 or Fz2 values. Additionally, there were no differences between the feet associated with the affected and unaffected hips for the FAI-s group. When comparing the larger and smaller Fz1 values for each person, all groups had a significant difference (p \u3c 0.005 for all). The FAI-s group had smaller Fz1 values than FAI-a group for both the left and right foot transition (1.57 ยฑ 0.34 BW vs. 1.81 ยฑ 0.20 BW, p=0.035 and 1.62 ยฑ 0.23 BW vs 1.81 ยฑ 0.13 BW, p=0.019, respectively). There was a trend toward Fz1 values being smaller for FAI-s when compared to OA for both foot transitions (p \u3c 0.08). There were no differences between the FAI-a and OA groups for Fz1 values and no differences between Fz2 values between any of the groups for either transition foot. CONCLUSION: Individuals with symptomatic FAI transition from stairs to floor with smaller impact forces when compared to the other groups, perhaps to avoid painful hip conditions. All participants had asymmetrical impact transition forces

    ํ•œ๊ตญ์ธ์—์„œ ๋Œ€์ •๋งฅ-์‹ฌ๋ฐฉ์ ‘ํ•ฉ๋ถ€๋ฅผ ๊ฒจ๋ƒฅํ•œ ์ค‘์‹ฌ์ •๋งฅ๋„๊ด€์˜ ๊นŠ์ด ์˜ˆ์ธก์„ ์œ„ํ•œ ์ž„์ƒ์—ฐ๊ตฌ

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    ํ•™์œ„๋…ผ๋ฌธ (์„์‚ฌ) -- ์„œ์šธ๋Œ€ํ•™๊ต ๋Œ€ํ•™์› : ์˜๊ณผ๋Œ€ํ•™ ์˜ํ•™๊ณผ, 2020. 8. ๋ฏผ์Šน๊ธฐ.Introduction: Central venous catheters (CVC) should be positioned at the cavoatrial junction (CAJ) or the right atrium. If catheters are inserted to a depth derived by adding the distance between the skin insertion point and the clavicular notch and the distance between the clavicular notch and the carina, the catheter tip can be placed near the carina. Based on that, this study aims to make a formula to place a catheter tip near the CAJ. Methods: This prospective nonrandomized interventional study included patients who needed a CVC from June 2017 to July 2018. The location of the CAJ was identified using a fluoroscopic technique. The following variables were measured: D1, the distance between the skin insertion point and the clavicular notch; D2, the vertical distance between the clavicular notch and the carina; and ฮฑ, the vertical distance between the carina and the CAJ. Results: A total of 70 patients were enrolled. The mean age was 65.5 ยฑ 11.6 years and 62.9% were male. The mean D1 and D2 were 7.6 ยฑ 1.4 and 7.0 ยฑ 1.4 cm, respectively. The mean ฮฑ was 4.4 ยฑ 1.5 cm (95% CI 4.1-4.8) and it was not affected by demographic factors, such as sex, age, height or weight. Conclusions: CVCs in adult patients can be placed near the CAJ using a simple formula: the distance between the skin insertion point and the clavicular notch + the vertical distance between the clavicular notch to the carina + 4.4 cm.ํ•ฉ๋ณ‘์ฆ์„ ์ค„์ด๊ธฐ ์œ„ํ•ด ์ค‘์‹ฌ์ •๋งฅ๋„๊ด€์˜ ๋์„ ๋Œ€์ •๋งฅ-์‹ฌ๋ฐฉ์ ‘ํ•ฉ๋ถ€๋‚˜ ์‹ฌ๋ฐฉ ์•ˆ์— ์œ„์น˜์‹œํ‚ค๋Š” ๊ฒƒ์ด ์ค‘์š”ํ•˜๋‹ค. ์ค‘์‹ฌ์ •๋งฅ๋„๊ด€์„ ํ”ผ๋ถ€์‚ฝ์ž…๋ถ€์™€ ๋น—์žฅํŒจ์ž„ ์‚ฌ์ด์˜ ๊ฑฐ๋ฆฌ์™€ ๋น—์žฅํŒจ์ž„๊ณผ ๊ธฐ๊ด€๋ถ„๊ธฐ๋ถ€ ์‚ฌ์ด์˜ ๊ฑฐ๋ฆฌ๋ฅผ ๋”ํ•œ ๋งŒํผ ๋„ฃ์œผ๋ฉด, ๋„๊ด€์˜ ๋์€ ๊ธฐ๊ด€๋ถ„๊ธฐ๋ถ€ ๊ทผ์ฒ˜์— ์œ„์น˜ํ•˜๊ฒŒ ๋œ๋‹ค. ์ด๋Ÿฐ ์‚ฌ์‹ค์„ ๋ฐ”ํƒ•์œผ๋กœ ์ค‘์‹ฌ์ •๋งฅ๋„๊ด€์„ ๋Œ€์ •๋งฅ-์‹ฌ๋ฐฉ์ ‘ํ•ฉ๋ถ€์— ์œ„์น˜์‹œํ‚ค๊ธฐ ์œ„ํ•œ ์‚ฝ์ž…๊ฑฐ๋ฆฌ๋ฅผ ๊ตฌํ•˜๋Š” ๊ณต์‹์„ ๋งŒ๋“ค๊ณ ์ž ํ•˜์˜€๋‹ค. ์ „ํ–ฅ์  ๋น„๋ฌด์ž‘์œ„ ์ž„์ƒ์‹œํ—˜์„ ์‹œํ–‰ํ•˜์˜€๊ณ , 2017๋…„ 7์›”๋ถ€ํ„ฐ 2018๋…„ 8์›”๊นŒ์ง€ ์ค‘์‹ฌ์ •๋งฅ๋„๊ด€ ์‚ฝ์ž…์ด ํ•„์š”ํ•œ ํ™˜์ž๋ฅผ ๋Œ€์ƒ์œผ๋กœ ์—ฐ์†์ ์œผ๋กœ ๋ชจ์ง‘ํ•˜์˜€๋‹ค. ๋Œ€์ •๋งฅ-์‹ฌ๋ฐฉ์ ‘ํ•ฉ๋ถ€์˜ ์œ„์น˜๋Š” ์ˆ˜์ˆ ์šฉ ํˆฌ์‹œ์œ ๋„ ํ•˜์— ํ™•์ธ์„ ํ•˜์˜€๋‹ค. ์•„๋ž˜์˜ 3๊ฐ€์ง€ ๊ฑฐ๋ฆฌ๋ฅผ ์‹œ์ˆ  ์ค‘์— ์ธก์ •ํ•˜์˜€๋‹ค: ๊ฑฐ๋ฆฌ 1, ์‚ฝ์ž…๋ถ€์™€ ๋น—์žฅํŒจ์ž„ ์‚ฌ์ด์˜ ๊ฑฐ๋ฆฌ; ๊ฑฐ๋ฆฌ 2, ๋น—์žฅํŒจ์ž„๊ณผ ๊ธฐ๊ด€๋ถ„์ง€๋ถ€ ์‚ฌ์ด์˜ ์ˆ˜์ง ๊ฑฐ๋ฆฌ; ๊ฑฐ๋ฆฌ 3, ๊ธฐ๊ด€๋ถ„์ง€๋ถ€์™€ ๋Œ€์ •๋งฅ-์‹ฌ๋ฐฉ์ ‘ํ•ฉ๋ถ€ ์‚ฌ์ด์˜ ์ˆ˜์ง ๊ฑฐ๋ฆฌ. ์ด 70๋ช…์˜ ํ™˜์ž๊ฐ€ ๋ถ„์„ ๋˜์—ˆ๋‹ค. ํ™˜์ž์˜ ํ‰๊ท  ๋‚˜์ด๋Š” 65.5 ยฑ 11.6 ์„ธ์˜€๊ณ , 62.9%๋Š” ๋‚จ์„ฑ์ด์—ˆ๋‹ค. ๊ฑฐ๋ฆฌ 1๊ณผ 2์˜ ํ‰๊ท ๊ฐ’์€ 7.6 ยฑ 1.4 ์™€ 7.0 ยฑ 1.4 cm ์˜€๋‹ค. ๊ฑฐ๋ฆฌ 3์˜ ํ‰๊ท ๊ฐ’์€ 4.4 ยฑ 1.5 cm (95% CI 4.1-4.8) ์˜€๊ณ , ์ด ๊ฐ’์€ ํ™˜์ž์˜ ๋‚˜์ด, ํ‚ค, ์„ฑ๋ณ„, ์ฒด์ค‘ ๋“ฑ์— ์˜ํ–ฅ์„ ๋ฐ›์ง€ ์•Š์•˜๋‹ค. ํ•œ๊ตญ ์„ฑ์ธ์—์„œ ์•„๋ž˜์˜ ๊ณต์‹์„ ์‚ฌ์šฉํ•˜์—ฌ ์ค‘์‹ฌ์ •๋งฅ๋„๊ด€์˜ ๋์„ ๋Œ€์ •๋งฅ-์‹ฌ๋ฐฉ์ ‘ํ•ฉ๋ถ€ ๊ทผ์ฒ˜์— ์œ„์น˜์‹œํ‚ฌ ์ˆ˜ ์žˆ๋‹ค. ์ด ์‚ฝ์ž… ๊ธธ์ด = ์‚ฝ์ž…๋ถ€์™€ ๋น—์žฅํŒจ์ž„ ์‚ฌ์ด์˜ ๊ฑฐ๋ฆฌ + ๋น—์žฅํŒจ์ž„๊ณผ ๊ธฐ๊ด€๋ถ„์ง€๋ถ€ ์‚ฌ์ด์˜ ์ˆ˜์ง ๊ฑฐ๋ฆฌ + 4.4 cm.Introduction 1 Materials and Methods 3 Results 9 Discussion 15 Conclusion 18 References 19 Abstract in Korean 21Maste

    Peranan Industri Dan Perguruan Tinggi Dalam Penemuan, Inovasidan Alm Teknowgi Menuju Hak Cipta Dan Hak Paten

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    Perkembangan ilmu pengetahuan dan teknologi dimanfaatkan olehmanusia untuk mengatasi kesuIitan-kesuIitan dan memenuhi kebutuhanhidup. Bangsa atau manusia di negara maju dapat memanfaatkan teknologimutakhir, sementara sebagian besar manusia yang lain menanggungdampak negatif sebagai akibat penerapan teknologi. Manusia mencarialternatif teknologi yang akan dikembangkan dan diterapkan, denganmelakukan pengkajian terhadap teknologi, agar dapat memanfaatkanteknologi seoptimal mungkin dengan mengantisipasi dampak negatifyang mungkin teIjadi.JImu pengetahuan manusia terdiri dari 4 ranah: Descriptive,Prescriptive, Ponnal Knowledge dan Praxiology, mempunyai hubungantimbal Balik dengan kehidupan manusia yang memiliki empat sistemideology, sociology, technology, dan environment. Pengembangan danpenerapan IPTEK bersumber dari penemuan dan inovasi, atau lewat alihteknologi dari negara maju dengan mempertimbangkan keuntungan danresiko yang mungkin teIjadi. Penemuan dan inovasi yang dilakukan olehpara perguruan tinggi, perIu ditunjang dan didukung oleh peraturan danpengakuan legalitas hak cipta dan paten sebagai intelectual right.Beberapa keiJdala yang dialaroi perguruan tinggi dalam mewujudkanhak cipta dan hak paten terhadap hasil temuan: (1) kurang tersedianyadana, (2) rendahnya motivasi untukpenelitian dasar, (3) belummemadainya penghargaan fmansiil terhadap penemuan,(4) terbatasnyatenaga profesional dalam penelitian dasar, (5)penelitian di perguruantinggi kurang terkait dengan teknologi yimg diterapkan industri, (6)pemahaman tentang hak paten dan hak cipta masih kurang, dan (7)belum ada upaya nyata untuk memasyarakatkan peraturan hak cipta danhak paten di lingkungan kampus. , .Ada tiga hal yang perIu diperhatiklin dalam pengusulan hak ciptadan hak paten: persyaratan, organisasl, dan prosedur pelaksanaan.Prosedur pengajuan usulan melalui 4 tahapan: (a) usulan pengajuanpenemuan; (b) kelengkapan lampiran bukti hasil temuan, gambar disaindari hasil penemuan, dan pernyataan tentang hasil temuan; (c) menyampaikanusulan kepada Ketua Jurusan dan Dekan, dan diteruskan ke panitiadaerah; (d) pengesahan oleh Rektor dan diajukan ke Panitia Nasionallewat Direktorat Pembinaan Penelitian dan Pengabdian pada Masyarakat

    Pharmaceutical-embodied technical progress, longevity, and quality of life: drugs as "equipment for your health"

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    Several econometric studies have concluded that technical progress embodied in equipment is a major source of manufacturing productivity growth. Other research has suggested that, over the long run, growth in the U.S. economy's 'health output' has been at least as large as the growth in non-health goods and services. One important input in the production of health pharmaceuticals is even more R&D- intensive than equipment. In this paper we test the pharmaceutical-embodied technical progress hypothesis the hypothesis that newer drugs increase the length and quality of life and estimate the rate of progress. To do this, we estimate health production functions, in which the dependent variables are various indicators of post-treatment health status (such as survival, perceived health status, and presence of physical or cognitive limitations), and the regressors include drug vintage (the year in which the FDA first approved a drug's active ingredient(s)) and indicators of pre-treatment health status. We estimate these relationships using extremely disaggregated prescription- level cross-sectional data derived primarily from the 1997 Medical Expenditure Panel Survey. We find that people who used newer drugs had better post-treatment health than people using older drugs for the same condition, controlling for pre-treatment health, age, sex, race, marital status, education, income, and insurance coverage: they were more likely to survive, their perceived health status was higher, and they experienced fewer activity, social, and physical limitations. The estimated cost of the increase in vintage required to keep a person alive is lower than some estimates of the value of remaining alive for one month. One estimate of the cost of preventing an activity limitation is $1745, and the annual rate of technical progress with respect to activity limitations is 8.4%. People consuming newer drugs tend to experience greater increases (or smaller declines) in physical ability than people consuming older drugs. Most of the health measures indicate that the effect of drug vintage on health is higher for people with low initial health than it is for people with high initial health. Therefore in contrast to equipment-embodied technical progress economic inequality, pharmaceutical-embodied technical progress has a tendency to reduce inequality as well as promote economic growth, broadly defined.

    Composition Modulation of Ag_2Te Nanowires for Tunable Electrical and Thermal Properties

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    In this article, we demonstrated that composition modulation of Ag_2Te nanowires can be achieved during the self-templated transformation of Te nanowires into Ag_2Te nanowires during solution phase synthesis, which provides a mean to tune the carrier density of the Ag_2Te nanowires. Both nearly stoichiometric and Ag-rich nanowires have been synthesized, which give rise to p-type and n-type Ag_2Te nanocomposites after hot press, respectively. The electrical and thermal properties of the two kinds of samples have been measured. Theoretical modeling based on the near-equilibrium Boltzmann transport equations has been used to understand the experimental results. We found that ZT of the heavily doped n-type sample reaches 0.55 at 400 K, which is the highest ZT value reported for Ag_2Te at the same temperature mainly due to the reduced thermal conductivity by the nanostructures. Theoretical analysis on the carrier transport shows that the power factor is also very well optimized in the doped Ag_2Te sample considering the reduced carrier mobility by the nanostructures

    Calculation of reflection wave transit time and paired data analysis

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    Expression analysis of low temperature-induced genes in wheat

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    Non-Peer ReviewedWheat (Triticum aestivum L.) is a widely adapted, economically important crop exhibiting winter, spring and intermediate growth habits. Winter wheat is seeded in the fall, over-winters, resumes growth in spring and is harvested in early summer. It also requires a period of low temperature (LT) exposure, experienced during the fall, to switch from the vegetative to reproductive phase in spring, a process known as vernalization. Low temperature also allows the wheat plant to cold-acclimate to withstand freezing winter temperatures. There has always been an interest to grow winter wheat because of its yield advantage over spring wheat. However, LT tolerance needs to be improved to prevent winter kill and maximize its yield potential. To achieve this more detailed understanding of molecular mechanisms underlying LT tolerance is required. Thus, objectives of this study were to determine the expression of a LT-induced gene and cDNA-AFLP profile in leaf and crown tissues of LT-exposed wheat plants. Survival of crown tissues after exposure to sub-zero temperatures is an indication of the level of LT tolerance of a cultivar. Thus, pattern and levels of expression of LT-induced genes and identification of LT-induced transcripts in this tissue will add to understanding of LT tolerance. Genotypes used in this study included a winter hardy cultivar, Norstar, a tender spring cultivar, Manitou and two-near-isogenic lines with the Vrn-A1 (spring Norstar) and vrn-A1 (winter Manitou) alleles of Manitou and Norstar, respectively. The dominant Vrn-A1 locus confers spring habit and therefore no requirement for vernalization. Quantitative real-time polymerase chain reaction (QPCR) for the cold-regulated gene, Wcor410, indicated that in leaf tissue the Vrn-A1 locus determined level of expression, being higher in the lines having the recessive vrn-A1 allele compared to the dominant Vrn-A1 allele lines. In the crown tissue, the Norstar genetic background led to the higher level of expression than in the Manitou background. cDNA-AFLP analysis also exhibited variable profiles between the two tissues
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