203 research outputs found
Multidisciplinary marine fisheries resources management
World fisheries have been beset by problems such as the over exploitation of resources, a restricted approach to fisheries problems, marine pollution and the establishment of exclusive economic zones. The purpose of this paper is to present a summary of a modern, logical and systematic multidisciplinary approach tofisheries management for administrators
The efficacy of Herceptin therapies is influenced by the expression of other erbB receptors, their ligands and the activation of downstream signalling proteins
ErbB2 and EGFR are attractive oncology therapeutic targets as their overexpression in tumors predicts a poorer clinical outcome in a variety of epithelial malignancies. However, clinical results with therapeutic compounds targeting these receptors have been mixed. Therefore, there is a need for improved predictive biomarkers for these targeted therapeutics. In this study we analysed tissue microarrays of patients treated with combination chemotherapy and Herceptin for expression or phosphorylation of signalling proteins associated with erbB receptors to identify protein biomarkers that are predictive of breast cancer patient response. A comparison of expression or phosphorylation of these markers with patient outcome revealed that response to Herceptin depended not only on expression levels of erbB2 but also on expression of EGFR, expression of erbB ligands, expression of other receptors and phosphorylation of downstream proteins. Elucidating the biological effects of EGFR/erbB2 targeted therapeutics will enable patient tumor profiling to identify likely responders and the determination of biologically effective doses that allows chronic administration of these agents in order to maximise efficacy
Effective Operator Treatment of the Anharmonic Oscillator
We analyse the one dimensional quartic oscillator using the effective
operator methodology of Lee and Suzuki. We reproduce known results for low
lying energy eigenvalues.Comment: 9 Pages, Extended version with new references. To appear in
Phys.ReV.
A Guide to Precision Calculations in Dyson's Hierarchical Scalar Field Theory
The goal of this article is to provide a practical method to calculate, in a
scalar theory, accurate numerical values of the renormalized quantities which
could be used to test any kind of approximate calculation. We use finite
truncations of the Fourier transform of the recursion formula for Dyson's
hierarchical model in the symmetric phase to perform high-precision
calculations of the unsubtracted Green's functions at zero momentum in
dimension 3, 4, and 5. We use the well-known correspondence between statistical
mechanics and field theory in which the large cut-off limit is obtained by
letting beta reach a critical value beta_c (with up to 16 significant digits in
our actual calculations). We show that the round-off errors on the magnetic
susceptibility grow like (beta_c -beta)^{-1} near criticality. We show that the
systematic errors (finite truncations and volume) can be controlled with an
exponential precision and reduced to a level lower than the numerical errors.
We justify the use of the truncation for calculations of the high-temperature
expansion. We calculate the dimensionless renormalized coupling constant
corresponding to the 4-point function and show that when beta -> beta_c, this
quantity tends to a fixed value which can be determined accurately when D=3
(hyperscaling holds), and goes to zero like (Ln(beta_c -beta))^{-1} when D=4.Comment: Uses revtex with psfig, 31 pages including 15 figure
Social Capital and Trust in Collaborative Marketing Groups: the Case of Vegetable Clusters in the Southern Philippines
Over the past two decades, numerous studies have explored the role and the impact of social capital in organizations. Social capital helps overcome problems of institutional access to information, credit, the supply of farm inputs and the provision of government services. Despite the increasing number of studies, the role of social capital and trust in collaborative marketing arrangements for smallholder producers remains relatively unexplored. This study examines social capital among cluster marketing groups in three regions of the Southern Philippines. The results show that social capital in the form of affiliations and networks, social cohesiveness, open communication and trust had positive benefits for each of the cluster marketing groups
Towards a sustainable approach to clustering small-scale farmers to market their agricultural produce
The University of the Philippines Mindanao and Curtin University have been organising small-scale vegetable farmers in Mindanao into cluster marketing groups to improve their access to markets and returns from the sale of their vegetable products using the 8-Step Clustering Approach for Agroenterprise Development developed by the Catholic Relief Services (Philippines). This paper reports on an action research investigation with around 30 marketing clusters. Cluster marketing has led to: better and wider market access, improved prices, reduced costs, improved human capital and social capital, and higher incomes. However, the current process may not lead to sustainable cluster marketing without support and may lead to dependency. This paper discusses strategies to overcome key challenges identified and deficiencies in the current process and suggests changes to the 8-step process so that it may improve the chances of cluster success and sustainability
Experiences with the Catholic Relief Services' clustering process for agroenterprise development and some suggestions for improvement
An evaluation of the Catholic Relief Services’ (CRS) eight-step clustering approach to agroenterprise development was a key focus of the Australian Centre for International Agricultural Research (ACIAR) – Philippine Council for Agriculture, Aquatic and Natural Resources Research and Development (PCAARRD) horticulture project on ‘Enhancing the profitability of selected vegetable value chains in the southern Philippines’. The CRS approach encourages farmers to form small, collaborative marketing groups (clusters) and to facilitate the sustainable development of these clusters. The research, which used participative action learning and action research processes, identified that an enhanced clustering approach should incorporate processes that overcome issues such as: input financing arrangements to replace loans from informal moneylenders and traders; risks associated with production failures and pest and disease problems; maintaining relationships with buyers; and building group resilience and independence so that donor agencies have an exit strategy. The research findings suggest that to enhance the sustainability of the clusters the CRS eight-step process should be applied to three phases: (i) establishment, (ii) building resilience and (iii) implementing an exit strategy
Marketing Benefits Derived from Clustering: the Case of Vegetable Clusters in Mindanao
One of the most limiting constraints for improving the profitability of smallholder vegetable farmers is poor marketing. With the lack of knowledge and inability to negotiate with downstream buyers, farmers have little option other than to sell their products to the traditional market. To facilitate access to technical information, credit and institutional markets, smallholder farmers are forming collaborative marketing groups. Clustering is one form of collaborative marketing in which smallholder farmers are organized into small groups within a defined territory or geographic area. Using the CRS Eight Step Plan for Agro-enterprise Development, 29 clusters were formed in three provinces in the Southern Philippines. This study explores the various marketing benefits smallholder farmers have achieved after joining the cluster. After interviewing 61 vegetable farmers from 10 clusters using a structured questionnaire, results show that upon joining the cluster, farmers became more aware of their buyer’s preference for product quality and gained knowledge on how to properly handle and package their produce. Cluster farmers increased their income from vegetable farming by selling a greater product variety, a larger volume and gaining access to high value markets
Theory and Practice of Participatory Action Research and Learning with Cluster Marketing Groups in Mindanao, Philippines
Researching and developing new arrangements for marketing smallholder products in the transitional economies is complex and requires an agribusiness systems approach. One approach to addressing complex problems is for researchers to facilitate an action learning process with farmers and market intermediaries, while using an action research process to investigate the factors that enhance the chances of success for farmer groups. This paper reviews the literature on action learning, action research and participatory processes in an attempt to clarify some of the terminology and define the similarities and differences. It outlines research into a framework to improve the effectiveness and resilience of cluster marketing groups through the application of these processes to smallholder vegetable chains in Mindanao, the southern Philippines
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