T-RECs:Rapid and large-scale detection of recombination events among different evolutionary lineages of viral genomes

Background: Many computational tools that detect recombination in viruses are not adapted for the ongoing genomic revolution. A computational tool is needed, that will rapidly scan hundreds/thousands of genomes or sequence fragments and detect candidate recombination events that may later be further analyzed with more sensitive and specialized methods. Results: T-RECs, a Windows based graphical tool, employs pairwise alignment of sliding windows and can perform (i) genotyping, (ii) clustering of new genomes, (iii) detect recent recombination events among different evolutionary lineages, (iv) manual inspection of detected recombination events by similarity plots and (v) annotation of genomic regions. Conclusions: T-RECs is very effective, as demonstrated by an analysis of 555 Norovirus complete genomes and 2500 sequence fragments, where a recombination hotspot was identified at the ORF1-ORF2 junction

Demonstration of 5G Solutions for Smart Energy Grids of the Future: A Perspective of the Smart5Grid Project

As the complexity of electric systems increases, so does the required effort for the monitoring and management of grid operations. To solve grid performance issues, smart grids require the exchange of higher volumes of data, high availability of the telecommunication infrastructure, and very low latency. The fifth generation (5G) mobile network seems to be the most promising technology to support such requirements, allowing utilities to have dedicated virtual slices of network resources to maximize the service availability in case of network congestions. Regarding this evolving scenario, this work presents the Smart5Grid project vision on how 5G can support the energy vertical industry for the fast deployment of innovative digital services. Specifically, this work introduces the concept of network applications (NetApps), a new paradigm of virtualization that are envisioned to facilitate the creation of a new market for information technology (IT), small and medium enterprises (SMEs), and startups. This concept, and the open architecture that facilitates its implementation, is showcased by four real-life 5G-enabled demonstrators: (1) automatic fault detection in a medium voltage (MV) grid in Italy, (2) real-time safety monitoring for operators in high voltage (HV) substations in Spain, (3) remote distributed energy resources (DER) monitoring in Bulgaria, and (4) wide area monitoring in a cross-border scenario between Greece and Bulgaria

Demonstration of 5G Solutions for Smart Energy Grids of the Future: A Perspective of the Smart5Grid Project

As the complexity of electric systems increases, so does the required effort for the monitoring and management of grid operations. To solve grid performance issues, smart grids require the exchange of higher volumes of data, high availability of the telecommunication infrastructure, and very low latency. The fifth generation (5G) mobile network seems to be the most promising technology to support such requirements, allowing utilities to have dedicated virtual slices of network resources to maximize the service availability in case of network congestions. Regarding this evolving scenario, this work presents the Smart5Grid project vision on how 5G can support the energy vertical industry for the fast deployment of innovative digital services. Specifically, this work introduces the concept of network applications (NetApps), a new paradigm of virtualization that are envisioned to facilitate the creation of a new market for information technology (IT), small and medium enterprises (SMEs), and startups. This concept, and the open architecture that facilitates its implementation, is showcased by four real-life 5G-enabled demonstrators: (1) automatic fault detection in a medium voltage (MV) grid in Italy, (2) real-time safety monitoring for operators in high voltage (HV) substations in Spain, (3) remote distributed energy resources (DER) monitoring in Bulgaria, and (4) wide area monitoring in a cross-border scenario between Greece and Bulgaria