Flavor SU(3) analysis of charmless B meson decays to two pseudoscalar mesons

Global fits to charmless B --> PP decays in the framework of flavor SU(3) symmetry are updated and improved without reference to the \sin2\beta measured from the charmonium decay modes. Fit results directly constrain the (\bar\rho,\bar\eta) vertex of the unitarity triangle, and are used to predict the branching ratios and CP asymmetries of all decay modes, including those of the B_s system. Different schemes of SU(3) breaking in decay amplitude sizes are analyzed. The major breaking effect between strangeness-conserving and strangeness-changing decays can be accounted for by including a ratio of decay constants in tree and color-suppressed amplitudes. The possibility of having a new physics contribution to K \pi decays is also examined from the data fitting point of view.Comment: 22 pages and 2 figures; some comments and references added; more references added, version to appear in journa

Charging NO x Emitters for Health Damages: An Exploratory Analysis

We present a proof-of-concept analysis of the measurement of the health damage of ozone (O 3) produced from nitrogen oxides (NO x = NO + NO 2) emitted by individual large point sources in the eastern United States. We use a regional atmospheric model of the eastern United States, the Comprehensive Air Quality Model with eXtensions (CAMx), to quantify the variable impact that a fixed quantity of NO x emitted from individual sources can have on the downwind concentration of surface O 3, depending on temperature and local biogenic hydrocarbon emissions. We also examine the dependence of resulting ozone-related health damages on the size of the exposed population. The investigation is relevant to the increasingly widely used "cap and trade" approach to NO x regulation, which presumes that shifts of emissions over time and space, holding the total fixed over the course of the summer O 3 season, will have minimal effect on the environmental outcome. By contrast, we show that a shift of a unit of NO x emissions from one place or time to another could result in large changes in resulting health effects due to ozone formation and exposure. We indicate how the type of modeling carried out here might be used to attach externality-correcting prices to emissions. Charging emitters fees that are commensurate with the damage caused by their NO x emissions would create an incentive for emitters to reduce emissions at times and in locations where they cause the largest damage.surface ozone, NO x emissions, point sources, health impacts, mortality, morbidity, cap-and-trade

Charging NOx Emitters for Health Damages: An Exploratory Analysis

We present a proof-of-concept analysis of the measurement of the health damage of ozone (O3) produced from nitrogen oxides (NOx = NO + NO2) emitted by individual large point sources in the eastern United States. We use a regional atmospheric model of the eastern United States, the Comprehensive Air Quality Model with Extensions (CAMx), to quantify the variable impact that a fixed quantity of NOx emitted from individual sources can have on the downwind concentration of surface O3, depending on temperature and local biogenic hydrocarbon emissions. We also examine the dependence of resulting ozone-related health damages on the size of the exposed population. The investigation is relevant to the increasingly widely used “cap and trade” approach to NOx regulation, which presumes that shifts of emissions over time and space, holding the total fixed over the course of the summer O3 season, will have minimal effect on the environmental outcome. By contrast, we show that a shift of a unit of NOx emissions from one place or time to another could result in large changes in the health effects due to ozone formation and exposure. We indicate how the type of modeling carried out here might be used to attach externality-correcting prices to emissions. Charging emitters fees that are commensurate with the damage caused by their NOx emissions would create an incentive for emitters to reduce emissions at times and in locations where they cause the largest damage.surface ozone, NOx emissions, point sources, health impacts, mortality, morbidity, cap-and-trade

Initial-State Radiation Measurement of the e+e−−>π+π−π+π− Cross Section

We study the process e+e-→π+π-π+π-γ, with a photon emitted from the initial-state electron or positron, using 454.3  fb-1 of data collected with the BABAR detector at SLAC, corresponding to approximately 260 000 signal events. We use these data to extract the nonradiative σ(e+e-→π+π-π+π-) cross section in the energy range from 0.6 to 4.5 GeV. The total uncertainty of the cross section measurement in the peak region is less than 3%, higher in precision than the corresponding results obtained from energy scan data

Search for the Z1(4050)+ and Z2(4250)+ states in Bˉ0→χc1K−π+ and B+→χc1K0Sπ+

We search for the Z1(4050)+ and Z2(4250)+ states, reported by the Belle Collaboration, decaying to χc1π+ in the decays B̅ 0→χc1K-π+ and B+→χc1KS0π+ where χc1→J/ψγ. The data were collected with the BABAR detector at the SLAC PEP-II asymmetric-energy e+e- collider operating at center-of-mass energy 10.58 GeV, and correspond to an integrated luminosity of 429  fb-1. In this analysis, we model the background-subtracted, efficiency-corrected χc1π+ mass distribution using the Kπ mass distribution and the corresponding normalized Kπ Legendre-polynomial moments, and then test the need for the inclusion of resonant structures in the description of the χc1π+ mass distribution. No evidence is found for the Z1(4050)+ and Z2(4250)+ resonances, and 90% confidence level upper limits on the branching fractions are reported for the corresponding B-meson decay modes

From Women’s Rights Lawyer in Pakistan to a Precarious Life in Australia: Learning From Lived Experience

Internationally the number of people displaced is at an historical high. The United Nations High Commissioner for Refugees (UNHCR) estimated that there were more than 79.5 million people displaced by conflict or persecution at the end of 2019 (UNHCR 2019). Australia is one of a relatively small number of countries that annually resettles refugees from overseas. In accordance with its international obligations under the UN Convention Relating to the Status of Refugees, Australia also provides protection to people who arrive in Australia seeking asylum. Historically, however, Australia’s policy response to people seeking asylum has been particularly punitive, including the re-introduction of temporary forms of protection for those found to be refugees. The choice to participate in higher education is an important factor for many people seeking asylum in Australia (Hartley, Fleay, Baker, Burke, & Field, 2018). Further education can provide asylum seekers with important opportunities to develop and enhance capacities and knowledge to sustain their livelihoods; aiding resettlement, social inclusion, and personal life fulfilment (Fleay, Lumbus & Hartley, 2016). Despite this, access to Australian higher education remains a persistently difficult problem for people seeking asylum who are effectively locked out because of the temporary nature of their visas (Burke, Fleay, Baker, Hartley, & Field, 2020). Because of their visa status, people seeking asylum and refugees living on temporary visas are classified as international students and are therefore pushed to pay full fees. Further, these people lose the only welfare payment they are eligible to collect if they enrol in a program of study of over 12 months duration. This has created a subclass of asylum seekers and refugees who are effectively denied access further education in Australia, unless they are able to access one of the few fee-waiver scholarships offered by some Australian universities (Hartley et al., 2018). While the gendered issues that women refugees face in accessing education have been documented (Hatoss & Huijser, 2010; Harris, Chi & Spark; 2013; Watkins, Razee & Richters, 2012), there is little known about how women from asylum seeking backgrounds access, or participate in, higher education in Australia

QBD APPROACH TO ANALYTICAL METHOD DEVELOPMENT AND ITS VALIDATION FOR ESTIMATION OF LENVATINIB IN BULK AND PHARMACEUTICAL FORMULATION

Objective: The objective of this research was to develop a simple, very rapid, sensitive, accurate, precise reverse phase High-Performance Liquid Chromatography (RP-HPLC) technique for the estimation of Lenvatinib in bulk and its dosage form. Methods: To perform this study, we employed a central composite design (CCD) to make method robust and effective to create chromatographic database. The factor screening studies were performed using 2-factor 10-runs. The factors were selected as the mobile phase ratio and buffer pH. Results: The desirability value of the optimized model was found to be 0.869 and The optimized chromatographic condition was achieved on Enable C18 analytical column with 0.01M Ammonium acetate buffer pH 3.84: methanol (33.17:66.83 v/v) as the mobile phase and flow rate of 1 ml min-1 and detection wavelength was set to 240 nm. The retention time of Lenvatinib was found to be 5.122 min. Linearity was established for Lenvatinib in the range of 10-50 µg/ml with a correlation coefficient (r2=0.9995). The accuracy values were found to be in the range of 98–102%. Intraday precision and Interday precision were in prescribed (Less than 0.98% RSD). Robustness was found to be less than 1.22% RSD. Conclusion: The proposed method was useful for best analysis of Lenvatinib in Bulk pharmaceutical dosage forms. Central Composite Design was an effective tool for the proposed RP-HPLC method

Nonleptonic charmless two-body B→ATB \to AT decays

In this work we have studied hadronic charmless two-body B decays involving p-wave mesons in final state. We have calculated branching ratios of $B\to AT$ decays (where $A$ and $T$ denotes a $^3P_1$ axial-vector and a tensor meson, respectively), using $B \to T$ form factors obtained in the covariant light-front (CLF) approach, and the full effective Hamiltonian. We have obtained that $\mathcal{B}(B^{0} \to a_{1}^{+}a_{2}^{-}) =42.47 \times10^{-6}$, $\mathcal{B}(B^{+} \to a_{1}^{+}a_{2}^{0}) = 22.71 \times10^{-6}$, $\mathcal{B}(B \to f_{1}K_{2}^{*}) = (2.8-4) \times 10^{-6}$ (with $f_{1}=, f_{1}(1285),f_{1}(1420)$) for $\theta_{^{3}P_{1}} = 53.2^{\circ}$, $\mathcal{B}(B \to f_{1}(1420)K_{2}^{*}) = (5.91-6.42) \times 10^{-6}$ with $\theta_{^{3}P_{1}} = 27.9^{\circ}$, $\mathcal{B}(B \to K_{1}a_{2})= (1.7 - 5.7) [1-9.3] \times10^{-6}$ for $\theta_{K_{1}} = -37^{\circ} [-58^{\circ}]$ where $K_1 = K_1(1270), K_1(1400)$. It seems that these decays can be measured in experiments at $B$ factories. Additionally, we have found that $\mathcal{B}(B \to K_{1}(1270)a_{2})/\mathcal{B}(B \to K_{1}(1400)a_{2})$ and $\mathcal{B}(B \to f_1(1420)K_{2}^{*})/\mathcal{B}(B \to f_1(1285)K_{2}^{*})$ ratios could be useful to determine numerical values of mixing angles $\theta_{K_{1}}$ and $\theta_{^{3}P_{1}}$, respectively.Comment: 12 page

Search for b→u transitions in B±→[K∓π±π0]DK± decays

We present a study of the decays B±→DK± with D mesons reconstructed in the K+π-π0 or K-π+π0 final states, where D indicates a D0 or a D̅ 0 meson. Using a sample of 474×106 BB̅ pairs collected with the BABAR detector at the PEP-II asymmetric-energy e+e- collider at SLAC, we measure the ratios R±≡Γ(B±→[K∓π±π0]DK±)/Γ(B±→[K±π∓π0]DK±). We obtain R+=(5-10+12(stat)-4+2(syst))×10-3 and R-=(12-10+12(stat)-5+3(syst))×10-3, from which we extract the upper limits at 90% probability: R+<23×10-3 and R-<29×10-3. Using these measurements, we obtain an upper limit for the ratio rB of the magnitudes of the b→u and b→c amplitudes rB<0.13 at 90% probability

COLOROMETRIC DETERMINATION OF RANTIDINE HYDROCHLORIDE

A simple, precise and cost effective colorometric method have been developed for the estimation of Rantidine hydrochloride in its pharmaceutical formulations. RNH shows λmax at 520.0 nm. The drug follows the Beer-Lambert’s law. The method validated by following the analytical performance parameters suggested by the International Conference on Harmonization. All validation parameters were within the acceptable range. The developed methods were successfully applied to estimate the amount of RNH in pharmaceutical dosage form