Caricature politique italienne à sujet médico-pharmaceutique

Caricature politique italienne à sujet médico-pharmaceutique. In: Revue d'histoire de la pharmacie, 71ᵉ année, n°259, 1983. p. 333

Prematür Ejakülasyon Hastalarında Mizaç ve Karakter Farklılıkları

Giriş: Prematür ejakülasyon’un etiyolojisi ile ilgili çok miktarda biyolojik ve psikolojiteorilerin olmasına karşın tartışmalar hala sürmektedir. Mizaç ve karakter envanteile prematür ejakülasyonlu hastaların kişilik yapısını araştırmayı amaçladık. Yöntem: Kırk prematür ejakülasyonlu hasta, 40 sağlıklı kontrol grubuyla eşleştirildÇalışmaya katılanlardan mizac ve karakter envanteri ve genel demografik bilgi formunu doldurması istendi. Bulgular: Toplam yenilik arayışı ve alt ölçeği keşfetme ve heyacan duyma prematür ejakülasyonlu hastalarda kontrol grubuna göre anlamlı olarak yüksek(p<0,05). Toplam zarardan kaçınma ve alt ölçeği belirsizlik korkusu prematüejakülasyonlu hastalarda kontrol grubuna göre anlamlı olarak düşük bulund(p<0,05). Beck depresyon skorun da prematür ejakülasyonlu hastalar kontrol grubundan anlamlı olarak yüksekti. Sonuç: Prematür ejakülasyonlu kişiler daha dürtüsel (heyecanlı), daha öfkeldaha heyacanlı ve zararlı davranışlara daha az yatkındılar. Mevcut bulgular prematür ejakülasyonun nörobiyolojik ve psikolojik kökenli olduğununu desteklemeğilimindedir. (Nöropsikiyatri Arşivi 2012; 49: 332-336)ntroduction: The debate on the etiology of premature ejaculation is still ongoing although there was huge amount of biological and psychological theories. We aimed to investigate the personality structure of patients with premature ejacula- ion via temperament and character inventory. Methods: Forty patients with premature ejaculation and a matched number of healthy people were included. Participants were asked to fill out a questionnaire booklet with separate sections for general demographic information and the tem- perament and character inventory. Results: Total novelty seeking scores and subscale 1 (exploration-excitability) cores in premature ejaculation patients were significantly higher than in control groups (p<0.05). Total harm avoidance scores and harm avoidance subscale 2 (fear of uncertainty) scores in premature ejaculation patients was found significantly low- er than in control group (p<0.05). Beck depression score was significantly higher in patients with premature ejaculation than in control groups. Discussion: Men with premature ejaculation are more impulsive (excitant), more empered, more excitable and less prone to harmful behavior. Current findings tend o reinforce premature ejaculation based upon combination of neurobiological and psychological reasons. (Arc&shy;hi&shy;ves of Neu&shy;ropsy&shy;chi&shy;atry 2012; 49: 332-336

Quality oflife, problem solving, focus of control and angertendencyinthe patients with acne

Amaç: Bu çalışmada akne hastalarının depresyon ve anksiyete düzeyleri, problem çözme, kontrol odağı, öfke eğilimi, yaşam kalitesi düzeyleri ve bunların aknenin klinik özellikleriyle ilişkisinin değerlendirilmesi amaçlandı. Gereç ve Yöntem: Çalışmamıza akne vulgaris tanısı konmuş 52 kişi ile 46 sağlıklı kontrol dahil edildi. Bütün hastalar, dermatolog tarafından akne şiddetine göre derecelendirildi. Katılımcılara Hamilton Anksiyete Değerlendirme Ölçeği (HAM-A) ve Montgomery-Asberg Depresyon Değerlendirme Ölçeği (MADRS) psikiyatrist (BE) tarafından uygulandı. Kısa Semptom Envanteri (KSE), Problem Çözme Envanteri (PÇE), Sürekli Öfke-Öfke Tarz Ölçeği (SOOTO) ve Rotter’in İç-Dış Kontrol Odağı Ölçeği (RİDKOÖ) ve SF-36 (Yaşam Kalitesi Kısa Form) uygulandı. Bulgular: Akne hastalarının depresyon ve anksiyete skorları kontrol grubuna göre anlamlı derecede yüksekti. Kısa semptom envanterinde akne hastalarının anksiyete bozukluğu, depresyon, kişiler arası duyarlılık ve paranoid düşünce skorları kontrol grubundan anlamlı derecede yüksek bulundu. SF-36 ölçeğine göre de fiziksel rol güçlüğü, genel sağlık ve mental sağlık skorları akne hastalarında kontrol grubuna göre anlamlı derecede düşüktü. Sonuç: Çalışmamızın sonuçları akne vulgarisin depresyon ve anksiyete gibi bazı psikiyatrik problemlere yol açtığı ve hastanın yaşam kalitesini olumsuz olarak etkilediği yönündeki önceki bulguları desteklemektedir. (Türk­derm 2014; 48: 177-81)Background and Design: In this study, we evaluated anxiety and depression levels, levels of problem solving, focus of control, tendency to anger and quality of life in patients with acne as well as the association between those parameters and the clinical features of acne. Materials and Methods: Fifty-two patients with mild to severe acne vulgaris and 46 healthy controls were enrolled. Acne severity was graded in all patients by a dermatologist. The Montgomery-Asberg Depression Rating Scale (MADRS), Hamilton Anxiety Rating Scale (HAM-A), Brief Symptom Inventory (BSI), Problem Solving Inventory (PSI), The State-Trait Anger Scale (STAS), Rotter’s Internal-External Focus of Control Scale (RIELCS) and the Short Form 36-Item Health Survey (SF-36) were applied to all participants. Results: In our study, we found out that anxiety and depression scores were significantly higher in patients with acne vulgaris than in controls. In BSI, anxiety disorders, depression, interpersonal sensitivity, and paranoid thoughts scores were significantly higher in patients with acne than in controls. According to SF-36, physical role difficulty, general health and mental health scores were significantly lower in patients with acne. Conclusion: The results of our study support the previous findings suggesting that acne vulgaris leads to various psychiatric problems, such as depression and anxiety and, adversely affects quality of life of patients. (Turkderm 2014; 48: 177-81

Prolidase activity and oxidative stress in patients with schizophrenia: A preliminary study

Selek, Salih/0000-0001-5197-5682WOS: 000349195700005PubMed: 25842545Objective: To determine whether serum prolidase levels are associated with the etiopathogenesis of schizophrenia. Methods: the study was conducted at the psychiatry outpatient clinics of the University Hospitals of Recep Tayyip Erdogan and Afyonkocatepe in spring 2013. It comprised patients with schizophrenia who were consecutively recruited from the Psychiatry outpatient clinics of the hospital. An equal number of healthy individuals were recruited from the community. Each patient underwent a detailed diagnostic evaluation by psychiatry residents by using the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-IV. Serum prolidase activity and oxidative parameters were measured in patient and control groups. the severity of psychotic symptoms was assessed using the positive and negative syndrome scale. SPSS 16 was used for statitistical analysis. Results: There were 30 subjects in each group, with 18(60%)females among the patients and 21(70%) among the controls. Serum prolidase level was significantly higher in schizophrenia patients compared to the controls (p<0.001). Total Oxidative Stress and Oxidative Stress Index parameters were found to be significantly different between the patients and the controls (p=0.024 and p<o.001). Serum prolidase level did not show any correlation with markers of oxidative stress in the patients. Conclusion: Prolidase activity, glutamate transmission and oxidative stress may be inter-related in the etiopathogenesis of schizophrenia

The role of obsessive beliefs in patients with major depressive disorder

WOS: 000331830900008PubMed: 24164496Aim. the aim of this study is to evaluate the differences in obsessional beliefs between patients with major depressive disorder (MDD) and matched healthy controls using the obsessive-beliefs questionnaire (OBQ). Methods. the study sample included 74 outpatients with MDD and 74 healthy subjects. the two groups were matched for age, gender, and education level. the diagnoses were based on the Diagnostic and Statistical Manual of Mental Disorder (DSM-IV). the severity of depression was measured with the Hamilton Depression Rating Scale (HAM-D). All participants filled out the 44-item OBQ. Results. the total and subscale OBQ scores [Responsibility/Threat Estimation (RT), Perfectionism/Certainly (PC), and Importance/Control of Thoughts (ICT)], were significantly higher in patients with MDD than those of the control group. There was a positive correlation between HAM-D scores and the OBQ subscale scores (RT, PC, and ICT) in the patients. Conclusion. Obsessional beliefs appear to be related to MDD

Nesfatin-1 ve yaygın anksiyete bozukluğu arasında ilişki var mı?

Amaç: Bu çalışmanın amacı yaygın anksiyete bozukluğu (YAB)’nun patogenezinde nesfatin-1’in olası rolünü araştırmaktır. Yöntem: Bu çalışmada 40 YAB’lu hasta ile yaş ve BMI ile eşleştirilmiş 42 sağlıklı kontrol’un plasma nesfatin-1 düzeyleri ölçüldü. Anksiyete şiddeti Hamilton Anksiyete Derecelendirme Ölçeği (HAM-A) ile değerlendirildi. Bulgular: Hasta ve kontrol grupları arasında nesfatin-1 düzeyinde anlamlı bir farklılık yoktur. Ortalama serum nesfatin-1 düzeyi yaş, hastalık süresi, BMI ve HAM-A skoru ile korelasyon göstermiyordu. Sonuç: Sonuçlarımız YAB‘nun nesfatin-1 ile ilişkili olduğunu desteklemiyor.Objective: The aim of the present study was to find out the possible role of nesfatin-1 in the pathogenesis of generalized anxiety disorder (GAD). Methods: In this study, we measured plasma nesfatin-1 levels in 40 GAD patients and 42 controls that were matched by age and BMI. The severity of anxiety was evaluated with the Hamilton Anxiety Rating Scale (HAM-A). Results: There was no statistically significant difference in the nesfatin-1 levels between patient and control groups. The mean serum nesfatin-1 level did not show any correlation with age, duration of illness, BMI, HAM-A scores in the patient and control groups. Conclusion: Our results do not support that nesfatin-1 is associated with GAD