ROSAT observations of two 'cooling flow' EMSS Galaxies

We present ROSAT observations of two luminous L~10^44 erg/s EMSS galaxies, MS1019+5139 and MS1209+3917, previously classified as 'cooling flow' galaxies. MS1019+5139 does not appear to be spatially extended (<13 kpc) while its spectrum is well fit by a power law with Gamma = 1.73 +0.19-0.18; X-ray variability on a timescale of ~ years is also clearly detected. MS1209+3917 shows no evidence of spatial extension (<50 kpc) but it shows variability, while its spectrum can be fit with thermal bremsstrahlung emission (kT=1.8 +0.9-0.4 keV) or a power law model (Gamma = 2.50 +0.44-0.42, but with excess photoelectric absorption above the Galactic value). All the above argue against thermal emission from a group of galaxies or a galaxy but in favour of an AGN (possibly BL Lac) interpretation. We conclude that no 'normal' galaxies with high X-ray luminosities have yet been detected in the EMSS survey that could be significant contributors to the X-ray background.Comment: 6 pages, LaTeX, 6 postscript figures included, to appear in MNRA

Causes and explanation of ''breakthrough phenomenon'' when LEM cooling system sublimator is fed with chlorinated feedwater

Comparison of chlorine or iodine use as feedwater bactericides in lunar excursion module cooling system sublimato

Integral Field Spectroscopy of a peculiar Supernova Remnant MF16 in NGC6946

We present a study of a peculiar Supernova Remnant MF16, associated with the Ultraluminous X-ray Source (ULX) NGC6946 ULX-1. Observations were taken with the MultiPupil Fiber Spectrograph (MPFS) with 6-m telescope on January 2005. The nebula is found to be highly asymmetric, one of the parts being much denser and colder. The two-component structure of the emission lines and radial velocity gradient argue for a non-spherical nebula, expanding with a velocity of about 100 km/s. Neither shock models nor the X-ray emission can adequately explain the actual emission line spectrum of MF16, so we suggest an additional ultraviolet source with a luminosity of about 10E40 erg/s. We confirm coincidence of the ULX with the central star, and identify radio emission observed by VLA with the most dense part of the nebula.Comment: Proceedings of the ESO and Euro3D Workshop "Science Perspectives for 3D Spectroscopy", Garching (Germany), October 10-14, 2005. M. Kissler-Patig, M.M. Roth and J.R. Walsh (eds.

Proteomics Strategies to Develop Proteins of Post-translational Modifications in Plasma-Derived Extracellular Vesicles as Disease Markers

Blood tests, which are the most wide spread diagnosis procedure in clinical analysis, apply blood biomarkers to categorize patients and support treatment decisions. However, existing biomarkers often lack specificity and are far from comprehensive. Mass spectrometry-based proteomics allow users to characterize plasma protein in great depth and has become a powerful tool in the biomarker discovery area. However, because of the extremely high dynamic range of plasma, being able identify thousands of plasma proteins using methods such as Liquid chromatography-tandem mass spectrometry (LC-MS/MS) remains a challenge. Furthermore, recent discoveries of extracellular vesicles (EVs) have proven that EVs have a high possibility for becoming the source for biomarker discovery and disease diagnosis. In addition to the protein in EVs, post-translation modification proteins (PTMs proteins) are also interesting targets because the PTMs proteins are involved with many cancer-related signaling transductions. This dissertation proposes proteomics strategies of using PTMs proteins in plasma-derived extracellular vesicles as breast cancer markers. Initially, Chapter One highlights the potential of using phosphoproteins in extracellular vesicles as markers for breast cancer. Chapter Two delves into the development of a pipeline proteomics strategy that utilizes glycoproteins in EVs as breast cancer markers. Finally, Chapter Three explores the details of different subtypes, which presents the possibility of leveraging three PTMs including phosphorylation, acetylation and glycosylation to distinguish three major breast cancer subtypes

A Passion for Security: Intervening to Help Software Developers

While the techniques to achieve secure, privacypreserving software are now well understood, evidence shows that many software development teams do not use them: they lack the ‘security maturity’ to assess security needs and decide on appropriate tools and processes; and they lack the ability to negotiate with product management for the required resources. This paper describes a measuring approach to assess twelve aspects of this security maturity; its use to assess the impact of a lightweight package of workshops designed to increase security maturity; and a novel approach within that package to support developers in resource negotiation. Based on trials in eight organizations, involving over 80 developers, this paper demonstrates that (1) development teams can notably improve their security maturity even in the absence of security specialists; and (2) suitably guided, developers can find effective ways to promote security to product management. Empowering developers to make their own decisions and promote security in this way offers a powerful grassroots approach to improving the security of software worldwide

Nullity conditions in paracontact geometry

The paper is a complete study of paracontact metric manifolds for which the Reeb vector field of the underlying contact structure satisfies a nullity condition (the condition \eqref{paranullity} below, for some real numbers $\tilde\kappa$ and $\tilde\mu$). This class of pseudo-Riemannian manifolds, which includes para-Sasakian manifolds, was recently defined in \cite{MOTE}. In this paper we show in fact that there is a kind of duality between those manifolds and contact metric $(\kappa,\mu)$-spaces. In particular, we prove that, under some natural assumption, any such paracontact metric manifold admits a compatible contact metric $(\kappa,\mu)$-structure (eventually Sasakian). Moreover, we prove that the nullity condition is invariant under $\mathcal{D}$-homothetic deformations and determines the whole curvature tensor field completely. Finally non-trivial examples in any dimension are presented and the many differences with the contact metric case, due to the non-positive definiteness of the metric, are discussed.Comment: Different. Geom. Appl. (to appear

Cyclic and ruled Lagrangian surfaces in complex Euclidean space

We study those Lagrangian surfaces in complex Euclidean space which are foliated by circles or by straight lines. The former, which we call cyclic, come in three types, each one being described by means of, respectively, a planar curve, a Legendrian curve of the 3-sphere or a Legendrian curve of the anti de Sitter 3-space. We also describe ruled Lagrangian surfaces. Finally we characterize those cyclic and ruled Lagrangian surfaces which are solutions to the self-similar equation of the Mean Curvature Flow. Finally, we give a partial result in the case of Hamiltonian stationary cyclic surfaces