2,828 research outputs found

    An Examination of the Impacts of Exchange Rate Volatility on Sectoral Trade in the Mercosur

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    This study captures the lack of macroeconomic policy coordination among Mercosur countries, through the impact of real bilateral exchange rate volatility on trade. A sectoral gravity model is estimated under two different measures of exchange rate volatility. Results show that the reduction in exchange rate volatility can increase bilateral trade.International Relations/Trade,

    Mentoring Entrepreneurial Networks : mapping conceptions of participants in technological-based business incubators in Brazil

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    La agenda de la investigación reciente sobre emprendedores incluye el análisis de las estructuras cognitivas de los empresarios de éxito, revelándose como una herramienta importante a la hora de examinar una trayectoria emprendedora. Mediante técnicas de mapas cognitivos, este estudio explora los conceptos de una trayectoria de éxito y la red en sí misma como un todo, para el desarrollo de esta carrera. Fueron estudiados 53 empresarios en siete viveros tecnológicos de la ciudad de Recife, Pernambuco, Brasil. El objetivo específico de este estudio era situar los significados comunes de los emprendedores del vivero teniendo en cuenta las redes de apoyo informal. Este tipo de redes ofrecen apoyo a la carrera empresarial, y el presente estudio examina tanto las características como el modelo conceptual que subyace bajo éstas. La recolección de datos fue realizada por medio de entrevistas a través de la técnica de evocación libre. Los significados comunes indican la existencia de categorías de pensamiento inherentes que fomentan el contexto de la red en el entorno del vivero, especialmente en las redes-mentor. Los resultados refuerzan la interpretación de un modelo mentor informal que emerge de las evocaciones predominantes respecto a una carrera de éxito y de la red en sí misma como promotora de su desarrollo.The recent entrepreneurship research agenda includes the analysis of cognitive structures of successful entrepreneurs, revealing an important tool for the examination of an entrepreneurial career. Using techniques of cognitive maps, this study explores the concepts of a successful career and the network itself, as a whole, for career development. Fifty-three entrepreneurs were studied, in seven technological incubators in the city of Recife, Pernambuco, Brazil. Specifically, this study aimed to map the shared meanings of the incubated entrepreneurs regarding informal support networks. Such networks support the entrepreneurial career and the present study explores the characteristics and the conceptual model that underlies the networks. The data collection was achieved through interviews through a free evocation technique. The shared meanings indicate the existence of inherent thought categories that support network context in the incubator environment, mainly the mentoring networks. The results endorse the interpretation of an informal mentoring model emerging from the dominant evocations concerning a successful career and of the network itself as promoter of career development

    Um método numérico para a modelagem de fraturamento coesivo em 3D

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    Neste trabalho apresenta-se um método que estende o modelo de fraturamento coesivo proposto por Hillerborg et ~ 1 . ~ 3 ' para problemas tri-dimensionais. O principal objetivo é o estudo do efeito das dimensóes absolutas de elementos de materiais ceramicos em seu comportamento estrutural. As hipóteses básicas e limitacóes de tal método sáo apresentadas e discutidas. O novo modelo obtido é entáo apresentado através da formulacáo matricial do problema coesivo. Esta formulacáo fornece um sistema de equacóes nao-lineares que pode ser resolvido com o algoritmo de Newton-Raphson. O modelo é capaz de representar a evolucáo das zonas de processos inelásticos e das de fissura verdadeira para diferentes geometrias estruturais2. A implementacáo computacional do modelo é feita utilizando-se técnicas de programacáo orientada para objetos e computacáo gráfica. Finalmente, apresenta-se um exemplo em que uma soluqáo tri-dimensional gerada com este modelo matemático é comparada com a solucao bi-dimensional conhecida na literatura.Peer Reviewe

    Flotation recovery of high-purity gibbsite concentrates from a Brazilian bauxite ore

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    Journal ArticleRecently research efforts have been made to obtain a high-purity gibbsite concentrate, suitable for first-class alumina refractories, from a Brazilian bauxite ore containing gibbsite (50%), quartz (35%),and kaolinite (15%). Detailed polished-section microprobe analysis was used to describe the liberation characteristics of the ore. Experimental results suggest that the kaolinite liberation characteristics can be described by King's liberation model and that only about 11% of the kaolinite is expected to be liberated at a particle size of 75 ÎĽ

    The chaperone balance hypothesis: The importance of the extracellular to intracellular HSP70 ratio to inflammation-driven type 2 diabetes, the effect of exercise, and the implications for clinical management

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    Recent evidence shows divergence between the concentrations of extracellular 70 kDa heat shock protein [eHSP70] and its intracellular concentrations [iHSP70] in people with type 2 diabetes (T2DM). A vital aspect regarding HSP70 physiology is its versatility to induce antagonistic actions, depending on the location of the protein. For example, iHSP70 exerts a powerful anti-inflammatory effect, while eHSP70 activates proinflammatory pathways. Increased eHSP70 is associated with inflammatory and oxidative stress conditions, whereas decreased iHSP70 levels are related to insulin resistance in skeletal muscle. Serum eHSP70 concentrations are positively correlated with markers of inflammation, such as C-reactive protein, monocyte count, and TNF-a, while strategies to enhance iHSP70 (e.g., heat treatment, chemical HSP70 inducers or coinducers, and physical exercise) are capable of reducing the inflammatory profile and the insulin resistance state. Here, we present recent findings suggesting that imbalances in the HSP70 status, described by the [eHSP70]/[iHSP70] ratio, may be determinant to trigger a chronic proinflammatory state that leads to insulin resistance and T2DM development. This led us to hypothesize that changes in this ratio value could be used as a biomarker for the management of the inflammatory response in insulin resistance and diabetes
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