17,510 research outputs found
Identifying short motifs by means of extreme value analysis
The problem of detecting a binding site -- a substring of DNA where
transcription factors attach -- on a long DNA sequence requires the recognition
of a small pattern in a large background. For short binding sites, the matching
probability can display large fluctuations from one putative binding site to
another. Here we use a self-consistent statistical procedure that accounts
correctly for the large deviations of the matching probability to predict the
location of short binding sites. We apply it in two distinct situations: (a)
the detection of the binding sites for three specific transcription factors on
a set of 134 estrogen-regulated genes; (b) the identification, in a set of 138
possible transcription factors, of the ones binding a specific set of nine
genes. In both instances, experimental findings are reproduced (when available)
and the number of false positives is significantly reduced with respect to the
other methods commonly employed.Comment: 6 pages, 5 figure
Simple model for quantum general relativity from loop quantum gravity
New progress in loop gravity has lead to a simple model of `general-covariant
quantum field theory'. I sum up the definition of the model in self-contained
form, in terms accessible to those outside the subfield. I emphasize its
formulation as a generalized topological quantum field theory with an infinite
number of degrees of freedom, and its relation to lattice theory. I list the
indications supporting the conjecture that the model is related to general
relativity and UV finite.Comment: 8 pages, 3 figure
Competing with stationary prediction strategies
In this paper we introduce the class of stationary prediction strategies and
construct a prediction algorithm that asymptotically performs as well as the
best continuous stationary strategy. We make mild compactness assumptions but
no stochastic assumptions about the environment. In particular, no assumption
of stationarity is made about the environment, and the stationarity of the
considered strategies only means that they do not depend explicitly on time; we
argue that it is natural to consider only stationary strategies even for highly
non-stationary environments.Comment: 20 page
The Collaborative Development of New CFD Methods Adapted for Tilt Rotor Aircraft in the HiPerTilt Project
No abstract available
Low energy onset of nuclear shadowing in photoabsorption
The early onset of nuclear shadowing in photoabsorption at low photon
energies has recently been interpreted as a possible signature of a decrease of
the rho meson mass in nuclei. We show that one can understand this early onset
within simple Glauber theory if one takes the negative real part of the rho N
scattering amplitudes into account, corresponding to a higher effective mass of
the rho meson in nuclear medium.Comment: REVTEX, 9 pages, including 4 eps figure
Evidence for spin liquid ground state in SrDyO frustrated magnet probed by muSR
Muon spin relaxation (SR) measurements were carried out on
SrDyO, a frustrated magnet featuring short range magnetic correlations
at low temperatures. Zero-field muon spin depolarization measurements
demonstrate that fast magnetic fluctuations are present from K down to
20 mK. The coexistence of short range magnetic correlations and fluctuations at
mK indicates that SrDyO features a spin liquid ground state.
Large longitudinal fields affect weakly the muon spin depolarization, also
suggesting the presence of fast fluctuations. For a longitudinal field of
T, a non-relaxing asymmetry contribution appears below K,
indicating considerable slowing down of the magnetic fluctuations as
field-induced magnetically-ordered phases are approached.Comment: 6 pages, 4 figures, to be published as a proceeding of HFM2016 in
Journal of Physics: Conference Series (JPCS
Probing 3-D matter distribution at z~2 with QSO multiple lines of sight
We investigate the 3-D matter distribution at z~2 with high resolution (R ~
40000) spectra of QSO pairs and groups obtained with the UVES spectrograph at
ESO VLT. Our sample is unique for the number density of objects and the variety
of separations, between 0.5 and 7 proper Mpc. We compute the real space
cross-correlation function of the Lyman-alpha forest transmitted fluxes. There
is a significant clustering signal up to ~2 proper Mpc, which is still present
when absorption lines with high column density (log N > 13.8) are excluded.Comment: Poster paper presented at the IAU Colloquium #199 on "Probing
Galaxies through Quasar Absorption Lines" held in Shanghai, China from March
14th to 18th, 200
Tomography of the intergalactic medium with Ly-alpha forests in close QSO pairs
We study the three-dimensional distribution of non virialised matter at z~2
using high resolution spectra of QSO pairs and simulated spectra drawn from
cosmological hydrodynamical simulations. We have collected the largest sample
of QSO pairs ever observed with UVES at the ESO-VLT, with angular separations
between ~1 and 14 arcmin. The observed correlation functions of the transmitted
flux in the HI Lyman alpha forest along and transverse to the lines of sight
are in good agreement implying that the distortions in redshift space due to
peculiar velocities are small. The clustering signal is significant up to
velocity separations of ~200 km/s, or about 3 h^{-1} comoving Mpc. The regions
at lower overdensity (rho/ < 6.5) are still clustered but on smaller
scales (Delta v < 100 km/s). The observed and simulated correlation functions
are compatible at the 3 sigma level. A better concordance is obtained when only
the low overdensity regions are selected for the analysis or when the effective
optical depth of the simulated spectra is increased artificially, suggesting a
deficiency of strong lines in the simulated spectra. We found that also a lower
value of the power-law index of the temperature-density relation for the Lyman
alpha forest gas improves the agreement between observed and simulated results.
If confirmed, this would be consistent with other observations favouring a late
HeII reionization epoch (at z~3). We remark the detection of a significant
clustering signal in the cross correlation coefficient at a transverse velocity
separation Delta v_{\perp} ~500 km/s whose origin needs further investigation.Comment: Accepted for publication in MNRAS, revised version matching the
accepted on
Leading strategies in competitive on-line prediction
We start from a simple asymptotic result for the problem of on-line
regression with the quadratic loss function: the class of continuous
limited-memory prediction strategies admits a "leading prediction strategy",
which not only asymptotically performs at least as well as any continuous
limited-memory strategy but also satisfies the property that the excess loss of
any continuous limited-memory strategy is determined by how closely it imitates
the leading strategy. More specifically, for any class of prediction strategies
constituting a reproducing kernel Hilbert space we construct a leading
strategy, in the sense that the loss of any prediction strategy whose norm is
not too large is determined by how closely it imitates the leading strategy.
This result is extended to the loss functions given by Bregman divergences and
by strictly proper scoring rules.Comment: 20 pages; a conference version is to appear in the ALT'2006
proceeding
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