12 research outputs found
Design of a modular robotic system that mimics small fish locomotion and body movements for ethological studies
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Decoding collective communications using information theory tools
Organisms have evolved sensory mechanisms to extract pertinent information from their environment, enabling them to assess their situation and act accordingly. For social organisms travelling in groups, like the fish in a school or the birds in a flock, sharing information can further improve their situational awareness and reaction times. Data on the benefits and costs of social coordination, however, have largely allowed our understanding of why collective behaviours have evolved to outpace our mechanistic knowledge of how they arise. Recent studies have begun to correct this imbalance through fine-scale analyses of group movement data. One approach that has received renewed attention is the use of information theoretic (IT) tools like mutual information, transfer entropy and causation entropy, which can help identify causal interactions in the type of complex, dynamical patterns often on display when organisms act collectively. Yet, there is a communications gap between studies focused on the ecological constraints and solutions of collective action with those demonstrating the promise of IT tools in this arena. We attempt to bridge this divide through a series of ecologically motivated examples designed to illustrate the benefits and challenges of using IT tools to extract deeper insights into the interaction patterns governing group-level dynamics. We summarize some of the approaches taken thus far to circumvent existing challenges in this area and we conclude with an optimistic, yet cautionary perspective
Analysis of flavonoids with unified chromatography-electrospray ionization mass spectrometry—method development and application to compounds of pharmaceutical and cosmetic interest
A Sensory-Driven Trade-Off between Coordinated Motion in Social Prey and a Predator’s Visual Confusion
Effects of water currents on fish migration through a Feynman-type path integral approach under Liouville-like quantum gravity surfaces
HTLV-1 bZIP factor supports proliferation of adult T cell leukemia cells through suppression of C/EBPα signaling
Background: Human T-cell leukemia virus type 1 (HTLV-1) is an oncogenic retrovirus etiologically associated with adult T-cell leukemia (ATL). The HTLV-1 bZIP factor (HBZ), which is encoded by minus strand of provirus, is expressed in all ATL cases and supports the proliferation of ATL cells. However, the precise mechanism of growth promoting activity of HBZ is poorly understood.Results: In this study, we showed that HBZ suppressed C/EBPα signaling activation induced by either Tax or C/EBPα. As mechanisms of HBZ-mediated C/EBPα inhibition, we found that HBZ physically interacted with C/EBPα and diminished its DNA binding capacity. Luciferase and immunoprecipitation assays revealed that HBZ repressed C/EBPα activation in a Smad3-dependent manner. In addition, C/EBPα was overexpressed in HTLV-1 infected cell lines and fresh ATL cases. HBZ was able to induce C/EBPα transcription by enhancing its promoter activity. Finally, HBZ selectively modulated the expression of C/EBPα target genes, leading to the impairment of C/EBPα-mediated cell growth suppression.Conclusion: HBZ, by suppressing C/EBPα signaling, supports the proliferation of HTLV-1 infected cells, which is thought to be critical for oncogenesis
Supramolecular Chemistry of Carbon Nanotubes
International audienceThis chapter aims to present recent examples of supramolecular functionalization of carbon nanotubes. The non-covalent functionalization appears as a solution for the future applications in nanotechnologies since it allows the functionalization and manipulation of nanotubes without the introduction of sp 3 defects in the π-conjugated system. Thus, the optical and electronic properties of the nanotubes remain preserved. In the first part of this chapter, we present the use of surfactant for the dispersion of nanotubes and its application for sorting. Then we report several examples of functionalization of nanotubes based on π-stacking interactions with pyrene derivatives. Finally, in the last part we review the wrapping of photo/electroactive polymers around the nanotube sidewalls. We put a particular focus on polyflurorene-based polymers and we show their utilization for the separation of nanotubes in diameter and chirality