51 research outputs found
Recommended from our members
Radiation effects in the environment
Although the Navajo possess substantial resource wealth-coal, gas, uranium, water-this potential wealth has been translated into limited permanent economic or political power. In fact, wealth or potential for wealth has often made the Navajo the victims of more powerful interests greedy for the assets under limited Navajo control. The primary focus for this education workshop on the radiation effects in the environment is to provide a forum where scientists from the nuclear science and technology community can share their knowledge toward the advancement and diffusion of nuclear science and technology issues for the Navajo public. The scientists will make an attempt to consider the following basic questions; what is science; what is mathematics; what is nuclear radiation? Seven papers are included in this report: Navajo view of radiation; Nuclear energy, national security and international stability; ABC`s of nuclear science; Nuclear medicine: 100 years in the making; Radon in the environment; Bicarbonate leaching of uranium; and Computational methods for subsurface flow and transport. The proceedings of this workshop will be used as a valuable reference materials in future workshops and K-14 classrooms in Navajo communities that need to improve basic understanding of nuclear science and technology issues. Results of the Begay-Stevens research has revealed the existence of strange and mysterious concepts in the Navajo Language of nature. With these research results Begay and Stevens prepared a lecture entitled The Physics of Laser Fusion in the Navajo language. This lecture has been delivered in numerous Navajo schools, and in universities and colleges in the US, Canada, and Alaska
Ontogeny of the circadian system during embryogenesis in rainbow trout (Oncorhynchus mykiss) and the effect of prolonged exposure to continuous illumination on daily rhythms of per1, clock, and aanat2 expression
It is widely held that the development of the circadian system during embryogenesis is important for future survival of an organism. Work in teleosts has been, to date, limited to zebrafish, which provides little insight into the diversity of this system within such a large vertebrate class. In this study, we analyzed the diel expression of per1, clock, and aanat2 in unfertilized rainbow trout oocytes and embryos maintained under either a 12:12 light:dark (LD) cycle or continuous illumination (LL) from fertilization. 24-h profiles in expression were measured at fertilization as well as 8, 21 42, and 57 days postfertilization (dpf). Both per1 and clock were expressed in unfertilized oocytes and all embryonic stages, while aanat2 expression was only measureable from 8 dpf. A reduction in both per1 and clock mean expression level between unfertilized oocytes/0-1dpf embryos and 8-9dpf embryos was suggestive of a transition from maternal RNA to endogenous mRNA expression. While aanat2 expression was not clearly associated with photic conditions, photoperiod treatment did alter the expression of per1 and clock expression/rhythmicity from as early as 8 dpf (per1), which could suggest the presence and functionality of an as yet unidentified “photoreceptor”. As a whole, this work demonstrates that clock systems are present and functional during embryonic development in rainbow trout. Further studies of their expression and regulation will help understand how the environment interacts with embryonic development in the species
The PHENIX Experiment at RHIC
The physics emphases of the PHENIX collaboration and the design and current
status of the PHENIX detector are discussed. The plan of the collaboration for
making the most effective use of the available luminosity in the first years of
RHIC operation is also presented.Comment: 5 pages, 1 figure. Further details of the PHENIX physics program
available at http://www.rhic.bnl.gov/phenix
Recommended from our members
Foil implosion studies on PEGASUS
PEGASUS is a 1.5 MJ capacitor bank facility used in the Los Alamos Trailmaster foil implosion program. The experiments on this facility are to serve as a diagnostic testbed and foil physics benchmark for foil implosions with explosive generators as drivers. During the first year of operation, foil implosions have been driven by discharging the bank directly into a very thin Aluminum 2500 /angstrom/ thick free-standing foil without any pulse sharpening techniques; so-called ''direct drive.''These direct drive experiments have served as initial tests to optimize bank performance and foil implosion experimental techniques. The results to date are presented below. 1 ref., 2 figs
Role of TMEM100 in mechanically insensitive nociceptor un-silencing
Mechanically silent nociceptors are sensory afferents that are insensitive to noxious mechanical stimuli under normal conditions but become sensitized to such stimuli during inflammation. Using RNA-sequencing and quantitative RT-PCR we demonstrate that inflammation upregulates the expression of the transmembrane protein TMEM100 in silent nociceptors and electrophysiology revealed that over-expression of TMEM100 is required and sufficient to un-silence silent nociceptors in mice. Moreover, we show that mice lacking TMEM100 do not develop secondary mechanical hypersensitivity—i.e., pain hypersensitivity that spreads beyond the site of inflammation—during knee joint inflammation and that AAV-mediated overexpression of TMEM100 in articular afferents in the absence of inflammation is sufficient to induce mechanical hypersensitivity in remote skin regions without causing knee joint pain. Thus, our work identifies TMEM100 as a key regulator of silent nociceptor un-silencing and reveals a physiological role for this hitherto enigmatic afferent subclass in triggering spatially remote secondary mechanical hypersensitivity during inflammation
Voices of Community Partners: Perspectives Gained from Conversations of Community-Based Participatory Research Experiences
Community-based participatory research (CBPR) has been documented as an effective approach to research with underserved communities, particularly with racial and ethnic minority groups. However, much of the literature promoting the use of CBPR with underserved communities is written from the perspective of the researchers and not from the perspective of the community partner. The purpose of this article is to capture lessons learned from the community partners’ insight gained through their experiences with CBPR. A multi-investigator consensus method was used to qualitatively code the transcripts of a CBPR story-telling video series. Seven major themes were identified: (1) expectations for engaging in research, (2) cultural humility, (3) respecting the partnership, (4) open communication, (5) genuine commitment, (6) valuing strengths and recognizing capacities, and (7) collaborating to yield meaningful results. The themes drawn from the community partner’s voice align with the tenets of CBPR advanced in the academic literature. More opportunities to include the community voice when promoting CBPR should be undertaken to help introduce the concepts to potential community partners who may be research cautious
- …