37 research outputs found
Super-resolving phase measurements with a multi-photon entangled state
Using a linear optical elements and post-selection, we construct an entangled
polarization state of three photons in the same spatial mode. This state is
analogous to a ``photon-number path entangled state'' and can be used for
super-resolving interferometry. Measuring a birefringent phase shift, we
demonstrate two- and three-fold improvements in phase resolution.Comment: 4 pages, 3 figure
Investigation of Coulomb stress changes in south Tibet (central Himalayas) due to the 25th April 2015 M W 7.8 Nepal earthquake using a Coulomb stress transfer model
Inadvertent malposition of a permanent pacemaker ventricular lead into the left ventricle which was initially missed and diagnosed two years later: a case report
Essential Features and Use Cases of the Cerebrospinal Fluid Proteome Resource (CSF-PR)
Every year, a large number of published studies present biomarkers for various neurological disorders. Many of these studies are based on mass spectrometry proteomics data and describe comparison of the abundance of proteins in cerebrospinal fluid between two or more disease groups. As the number of such studies is growing, it is no longer straightforward to obtain an overview of which specific proteins are increased or decreased between the numerous relevant diseases and their many subcategories, or to see the larger picture or trends between related diseases. To alleviate this situation, we therefore mined the literature for mass spectrometry–based proteomics studies including quantitative protein data from cerebrospinal fluid of patients with multiple sclerosis, Alzheimer’s disease, and Parkinson’s disease and organized the extracted data in the Cerebrospinal Fluid Proteome Resource (CSF-PR). CSF-PR is freely available online at http://probe.uib.no/csf-pr, is highly interactive, and allows for easy navigation, visualization, and export of the published scientific data. This chapter will guide the user through some of the most important features of the tool and show examples of the suggested use cases
Effect of brood size and hatching sequence on prefledging mortality of Sandwich terns: why lay two eggs?
Cost-effectiveness of surgery in low- and middle-income countries: a systematic review.
BACKGROUND: There is increasing interest in provision of essential surgical care as part of public health policy in low- and middle-income countries (LMIC). Relatively simple interventions have been shown to prevent death and disability. We reviewed the published literature to examine the cost-effectiveness of simple surgical interventions which could be made available at any district hospital, and compared these to standard public health interventions.
METHODS: PubMed and EMBASE were searched using single and combinations of the search terms "disability adjusted life year" (DALY), "quality adjusted life year," "cost-effectiveness," and "surgery." Articles were included if they detailed the cost-effectiveness of a surgical intervention of relevance to a LMIC, which could be made available at any district hospital. Suitable articles with both cost and effectiveness data were identified and, where possible, data were extrapolated to enable comparison across studies.
RESULTS: Twenty-seven articles met our inclusion criteria, representing 64 LMIC over 16 years of study. Interventions that were found to be cost-effective included cataract surgery (cost/DALY averted range US106.00), elective inguinal hernia repair (cost/DALY averted range US78.18), male circumcision (cost/DALY averted range US319.29), emergency cesarean section (cost/DALY averted range US3,462.00), and cleft lip and palate repair (cost/DALY averted range US96.04). A small district hospital with basic surgical services was also found to be highly cost-effective (cost/DALY averted 1 US32.78-1,062.00), vitamin A supplementation (US12.00), breast feeding promotion (US922.00).
CONCLUSIONS: Simple surgical interventions that are life-saving and disability-preventing should be considered as part of public health policy in LMIC. We recommend an investment in surgical care and its integration with other public health measures at the district hospital level, rather than investment in single disease strategies