Radiological Imaging and Analysis of Laboratory Values in Case of Acute Ischemic Stroke

Background: The rate of death and disability due to acute ischemic stroke ranks second in the world. In this study it was planned to analyze the demographic characteristics and additional diseases in the etiology as well as radiological imaging and laboratory values in patients with ischemic stroke. Materials and Methods: This study was conducted retrospectively by analyzing the patients hospitalized with the diagnosis of ischemic stroke from the emergency department between 01.01.2022 and 31.12.2022. Routine laboratory values, lipids, vitamin levels, radiological imaging and tests for etiology were analyzed in the patients. Results: One hundred seventy seven patients were analyzed in the study. 53.1% of the patients were male. The mean age was 75±12.75 years. The most common comorbidities were hypertension, diabetes and hyperlipidemia. As ischemic infarction, involvement was most common in the areas fed by the middle cerebral artery. In the carotid and/or vertebral doppler ultrasonography performed in the patients, plaque was observed in the vessels at a rate of 83.1%. According to the transthoracic echocardiographic findings, 79.3% of the patients were found to have heart valve pathology. Pathologically the majority of patients had hyperglycemia, vitamin D deficiency and low HDL cholesterol levels. Thrombolytic therapy was applied in six patients and three patients benefited and one patient died due to bleeding. 13.6% of the patients were treated in the intensive care unit. Conclusion: The risk of ischemic stroke increases in advanced age. Hypertension and diabetes are among the most important risk factors. Vitamin D and vitamin B12 deficiency and folic acid deficiency pose a risk in terms of atherosclerosis. At the same time, low HDL cholesterol levels increase the risk of stroke. These factors which are considered as preventable causes in etiology should be controlled with treatment

Reversal of Isoniazid-Induced Status Epilepticus Following Pyridoxine

Introduction: Intoxication caused by anti-tuberculosis drugs is a rare event in the modern era of medicine. However, high doses of isoniazid may cause convulsion, metabolic acidosis, lactic acidosis, rhabdomyolysis, coma, and eventually death

Mortality salience in professionals witnessing death: The effects of mortality manipulation on doctors' evaluations

This study investigates whether frequently witnessing death leads to desensitization in terms of death anxiety. A total of 163 individuals, comprising 71 doctors from branches with high death rates and 92 doctors from branches where mortality is rarely seen, participated in this study. An experiment was conducted employing a classical version of mortality salience manipulation, which is often used in terror management research, to test the study's hypothesis. The results supported the hypothesis only with regard to altruism-egoism, providing partial support for the effect of desensitization. This subject needs to be studied further

Desensitizing Effect of Frequently Witnessing Death in an Occupation: A Study With Turkish Health-Care Professionals

This study aimed to investigate anxiety and fear of death created by the consciousness of death in professionals who frequently witness death and to determine variables related to the dimensions of mortality awareness. Data were gathered from 212 health-care employees, primarily those in emergency medicine and intensive care. Variance analysis was used to assess sex and experience groups using the Bonferroni post hoc test. Hierarchical multiple regression analysis was used to determine the predictive relationships. Health-care employees' fear of death decreased with experience. No significant difference was observed between the experience groups in terms of conservatism values such as conformity, tradition, and security in the theory of basic human values. Empathy level was determined to be significantly predictive of the mortality awareness dimensions. These findings indicate a desensitization effect of witnessing the death, contrary to that predicted by the terror management theory

Is there a correlation between the diagnostic test results and the histopathological diagnoses of acute appendicitis in a Turkish hospital in Somalia?

Appendicitis is the most common cause of acute abdomen. This study aimed to investigate the demographic and clinical data of the patients diagnosed with acute appendicitis in the emergency department of a Turkish tertiary care center in Somalia. The association between the diagnostic test results and the histopathological diagnoses was also analyzed. Data of the patients diagnosed with acute appendicitis at the emergency department between the 1st of January 2021 and the 31st of December 2021 period were retrospectively reviewed. The demographic data, clinical features, laboratory test results and radiological and histopathological findings of the participants were retrieved from the hospital's electronic medical records for patients in the database. Overall, 83 patients were included. Among those, 59 (71.1%) were male, and the mean patient age was 22±8.2. The mean values of the leukocyte and neutrophil counts and the C-reactive protein levels were higher than the normal range. The laboratory test, abdominal ultrasonography, and enhanced computerized tomography results were compared with the histopathological findings. Only the neutrophil-lymphocyte ratio was found (to be) significant in the diagnosis of complicated appendicitis. The clinical data, laboratory tests, and radiological imaging findings should be evaluated together to diagnose acute appendicitis. Prompt diagnosis is essential for the prevention of postoperative complications and mortality. A statistically significant difference was found in the comparison of the lymphocyte counts, NLR values, and histopathological findings (p=0.01 and p=0.008). [Med-Science 2023; 12(4.000): 1301-5